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Extensively and partially hydrolysed infant formulas for allergy prophylaxis

Open access
Oldaeus, G, Anjou, K, Bjorksten, B, Moran, J R, Kjellman, N-I M·1997·Archives of Disease in Childhood

Abstract

The allergy preventive effect of extensively (N) and partially (PH) hydrolysed cows' milk formulas compared with a regular formula (RM) was assessed in 155 infants with a family history of allergy. No cows' milk was given during the first nine months of life and no egg and fish up to 12 months of age. Breast feeding mothers avoided the same foods. At weaning the infants were randomised to one of the formula groups. The cumulative incidence of atopic symptoms at 18 months was 51, 64, and 84% in the N, PH, and RM groups, respectively. From 6 to 18 months there were significantly less cumulative atopic symptoms in the N group compared with the RM group, and significantly less than the PH group up to 6 (N = 25%; PH = 46%) and 9 months (N = 34%, PH = 58%). At 9 months significantly fewer infants in the N group (10%) than in the PH group (33%) had a positive skin prick test to eggs. The findings support an allergy preventive effect of an extensively hydrolysed formula, but not of a partially hydrolysed formula, during the first 18 months of life of high risk infants.

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Metadata

Authors
Oldaeus, G., Anjou, K., Bjorksten, B., Moran, J. R., & Kjellman, N.-I. M.
Venue
Archives of Disease in Childhood
Publisher
BMJ
Published
1997-07-01
Volume
77
Issue
1
Pages
4-10
ISSN
  • 0003-9888 (ISSN-L)
  • 1468-2044
OpenAlex
W2147426463
Cited by
205
References
2
FWCI
5.33
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Extensively and partially hydrolysed infant formulas for allergy prophylaxis. https://app.cochat.ai/papers/10.1136/adc.77.1.4
The paper
Oldaeus, G., Anjou, K., Bjorksten, B., Moran, J. R., & Kjellman, N.-I. M. (1997). Extensively and partially hydrolysed infant formulas for allergy prophylaxis. Archives of Disease in Childhood. https://doi.org/10.1136/adc.77.1.4

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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