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Cited by 129Neonatal Respiratory Health ResearchRespiratory Support and MechanismsNeuroscience of respiration and sleep

The DOI matches its Crossref record; 54 of the 55 references it cites were found in a registry or an index.

Efficacy and safety of bubble CPAP in neonatal care in low and middle income countries: a systematic review

Martin, Simone, Duke, Trevor, Davis, Peter·2014·Archives of Disease in Childhood - Fetal and Neonatal Edition
DOI 10.1136/archdischild-2013-305519
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Abstract

Introduction: Forty per cent of global child deaths occur in the neonatal period. Low and middle income countries need effective and simple methods to improve hospital-based neonatal care. Bubble continuous positive airway pressure (CPAP) may have a role in improving the quality of respiratory support in hospitals in low and middle income countries. Aim: To examine the evidence for the efficacy and safety of bubble CPAP in neonates with respiratory distress in low and middle income settings. Method: A systematic search (1946–March 2014) was performed of Pubmed, Ovid MEDLINE, Web of Science, Google Scholar and the references of relevant articles. Articles meeting inclusion criteria (CPAP for respiratory distress in infants <28 days of age in hospitals in low and middle income countries) were assessed using Grading of Recommendations, Assessment, Development and Evaluation and Newcastle-Ottawa Quality Assessment Scale methodology. Outcomes included need for mechanical ventilation, complications and mortality. Results: In three studies, the initial use of bubble CPAP compared with oxygen therapy, followed by mechanical ventilation if required, reduced the need for mechanical ventilation by 30%–50%. In another three trials comparing bubble CPAP with ventilator CPAP, mortality and complication rates were similar, while meta-analysis of CPAP failure in these same trials showed a lower failure rate in the bubble CPAP groups (p <0.003). Conclusions: There is evidence that bubble CPAP is safe and reduces the need for mechanical ventilation. Further research into the efficacy of bubble CPAP in low-income and middle-income countries is needed.

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Crossref · 10.1136/archdischild-2013-305519

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Show all 55 references

Research works printed but not linked: 5

  1. Review Manager (RevMan) Version 5.2 [program]. Copenhagen: The Cochrane Collaboration, 2012.
  2. Rezzonico, 2012, Efficacy of low cost non invasive neonatal ventilation in Nicaragua, Ricerca Practica, 28, 193
  3. Angel, 2007, Beneviste's valve CPAP in a Latin-American NICU, J Perinat Med, 35, S106
  4. Mazmanyan, 2009, RCT of flow driver and bubble continuous positive airway pressure in pre-term infants in a resource-limited setting, Acta Paediatr, 98, 1
  5. Tejerina, 2010, A simple method for maintaining continuous positive airway pressure (CPAP) in preterm infants in low-income countries, Pediatr Res, 67, 449

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Metadata

Authors
Martin, S., Duke, T., & Davis, P.
Affiliations
  • Royal Children's Hospital (AU)
  • Royal Women's Hospital (AU)
Corresponding author
Martin, Simone
ORCID
Venue
Archives of Disease in Childhood - Fetal and Neonatal Edition
Publisher
BMJ
Published
2014-08-01
Volume
99
Issue
6
Pages
F495-F504
ISSN
  • 1359-2998 (ISSN-L)
  • 1468-2052
DOI
10.1136/archdischild-2013-305519
OpenAlex
W2148922604
Cited by
129
References
55
Citations by year
2026: 2 · 2025: 9 · 2024: 4 · 2023: 8 · 2022: 17 · 2021: 9 · 2020: 23 · 2019: 15 · 2018: 12 · 2017: 8 · 2016: 10 · 2015: 10 · 2014: 1
FWCI
1.66
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of Disease in Childhood Fetal & Neonatal (publishedVersion)
  • PubMed (publishedVersion)
  • HighWire Press Open Archive (submittedVersion)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Neonatal Respiratory Health Research
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroscience of respiration and sleep
Keywords
bubble CPAP, neonatal respiratory distress, neonatal respiratory support, mechanical ventilation reduction, CPAP failure, CPAP complications, neonatal mortality, low- and middle-income countries, oxygen therapy
MeSH terms
Humans, Infant, Newborn, Infant, Premature, Oxygen Inhalation Therapy, Research Design, Respiratory Distress Syndrome, Newborn, Intensive Care, Neonatal, Continuous Positive Airway Pressure

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