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Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay.

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ROLE OF MECHANICAL FACTORS IN PATHOGENESIS OF PRIMARY OSTEOARTHRITIS

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Low‐level increases in serum C‐reactive protein are present in early osteoarthritis of the knee and predict progressive disease

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Rapid equilibrium radioimmunoassay for the amino-terminal propeptide of human type III procollagen.

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Innate immunity and Toll-like receptors

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A 2-year evaluation of disease progression by quantitative magnetic resonance imaging in a large primary osteoarthritic patient population

Raynauld, J.-P., Pelletier, J., Berthiaume, M.-J., Beaudoin, G., Labonté, F., Bloch, D. A., Choquette, D., Haraoui, B. P., Altman, R. D., Hochberg, M. C., et al. (2004) · Arthritis Research · doi:10.1186/ar1362

Mapping out the mitogen activated protein kinase pathway

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Tumor necrosis factor alpha downregulates bone morphogenetic protein expression and matrix macromolecule synthesis in articular cartilage

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A noninvasive magnetic resonance imaging-based method for assessing patellofemoral joint kinematics detects differences between healthy and symptomatic knees

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Tissue destruction in arthritis : Experimental studies

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Hyper-ERAD: a novel pathomechanism for rheumatoid arthritis

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Analysis of IgVH-specific, CXCR4-specific and CXR5-specific mRNA transcripts in individual peripheral blood B cells of patients with primary Sjögren's syndrome and normal healthy subjects

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Differential modulation of cysteinyl leukotriene receptor 1 and 2 expression by distinct Toll-like receptor agonists in monocyte-derived dendritic cells

Rola‐Pleszczynski, M., Thivierge, M., & Staňková, J. (2004) · Arthritis Research · doi:10.1186/ar1397

Differential gene expression and regulation of the bone morphogenic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts

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Insights into systemic lupus erythematosus pathogenesis through blood global gene expression analysis

Pascual, V., Bennett, L. B., Allantaz, F., Arce, E., & Banchereau, J. (2004) · Arthritis Research · doi:10.1186/ar1380

Cross-sectional association between urinary type II collagen C- terminal telopeptide concentration and radiographic spinal disc degeneration

Sakoda, J., Ishijima, M., & Kurosawa, H. (2009) · Juntendō Igaku/Juntendo igaku · doi:10.14789/pjmj.55.54

Regulation of B-cell tolerance by complement C4

Alimzhanov, M. B., Imanishi‐Kari, T., & Carroll, M. (2004) · Arthritis Research · doi:10.1186/ar1378

Quantitative measurements of articular cartilage by magnetic resonance imaging

Hall, L., Burge, J., Evans, S., & Poole, R. (2004) · Arthritis Research · doi:10.1186/ar1390

An apoptotic signaling pathway activated by Nod1

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Different molecules at the surface of stimulated T cells induce IL-1α, tumor necrosis factor and IL-1 receptor antagonist in human monocytes

Burger, D., Molnarfi, N., Gruaz, L., & Dayer, J. M. (2004) · Arthritis Research · doi:10.1186/ar1426

Abnormal collagen type I production in osteoarthritic subchondral bone is associated with a reduced capacity of osteoblasts to mineralize in vitro

Aubry, I., Delalandre, A., Fernandes, J., Pelletier, J., Pelletier, J.-P., & Lajeunesse, D. (2004) · Arthritis Research · doi:10.1186/ar1422

Synergistic interactions of proinflammatory cytokines with oncostatin M: production of active collagenases and implications for joint destruction

Cawston, T. (2004) · Arthritis Research · doi:10.1186/ar1383

The use of imaging and biomarkers in the assessment and follow-up of arthritis

Emery, P. (2004) · Arthritis Research · doi:10.1186/ar1363

Menopause and hormone replacement therapy: effects on the immune system, arthritis and bone

Carlsten, H., Forsblad‐d’Elia, H., Erlandsson, M. C., & Islander, U. (2004) · Arthritis Research · doi:10.1186/ar1371

Markers in rheumatoid arthritis

Breedveld, F. C. (2004) · Arthritis Research · doi:10.1186/ar1365

Aggrecan fragments as biomarkers in osteoarthritis

Larsson, S. (2010) · Lund University Publications (Lund University)

The role of TLR4 and neutrophil expression in infection-triggered arthritis

Zhang, X., Glogauer, M., Zhu, F., Kim, T., Chiu, B., & Inman, R. (2004) · Arthritis Research · doi:10.1186/ar1412

Pharmacokinetic–pharmacodynamic modeling considering spinal and peripheral actions of nonsteroidal antiinflammatory drugs to optimize the treatment of inflammation-induced pain

Castañeda‐Hernández, G., Ortiz, M. I., Lozano‐Cuenca, J., Torres‐López, J. E., & Granados‐Soto, V. (2004) · Arthritis Research · doi:10.1186/ar1375

Distinct lymphocyte subpopulations in bone marrow from rheumatoid arthritis and osteoarthritis patients: a role for IL-15?

Maśliński, W., Kuca‐Warnawin, E., Burakowski, T., Jung, L. K. L., & Małdyk, P. (2004) · Arthritis Research · doi:10.1186/ar1420

Antibody-initiated organ injury: apoptosis, inflammation and fibrosis in neonatal lupus

Buyon, J. P., & Clancy, R. M. (2004) · Arthritis Research · doi:10.1186/ar1366

Joint health: What degree of evidence is necessary to support health claims for food supplements, taking glucosamine as an example?

Bernhardt, J. H., Jaenicke, C., Prock, P., & Schneider, U. (2015) · Nutrafoods · doi:10.1007/s13749-015-0018-9

Cytokine networks in human severe combined immunodeficiency: a model for regulating T-cell homeostasis

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New emerging roles of transcription factor Pitx1 and Reg growth factors in osteoarthritis pathogenesis

Moreau, A., Wang, D., Jacques, S., Chassaing, C., Landreville, V., Pelletier, J., & Fernandes, J. (2004) · Arthritis Research · doi:10.1186/ar1415

Lymphoid chemokine expression in Sjogren's syndrome: relationship with the lymphoid organization of the periductal inflammatory aggregates

Barone, F., Bombardieri, M., Blades, M. C., Manzo, A., Morgan, P. R., Challacombe, S., Valesini, G., & Pitzalis, C. (2004) · Arthritis Research · doi:10.1186/ar1409

RANK and RANKL expression in RA synovium and lymph nodes as markers of dendritic cell-T cell interactions

Page, G., & Miossec, P. (2004) · Arthritis Research · doi:10.1186/ar1398

Differential induction of IL-1β and tumor necrosis factor by CD40 ligand or cellular contact with stimulated T cells depends on the degree of maturity of human monocytes

Burger, D., Molnarfi, N., Gruaz, L., & Dayer, J. M. (2004) · Arthritis Research · doi:10.1186/ar1394

Magnetic resonance imaging, X-ray and dual X-ray absorptiometry techniques for assessment and monitoring of knee osteoarthritis

Boulos, P., Inglis, D., Beattie, K. A., Ioannidis, G., Gordon, C. L., Duryea, J., Webber, C. E., & Adachi, J. D. (2004) · Arthritis Research · doi:10.1186/ar1437

Immune tolerance: DNA vaccine as strategy in autoimmune diseases

Djilali-Saiah, I. (2004) · Arthritis Research · doi:10.1186/ar1393

Comparison of urinary excretion of Deoxypiridinoline and value of serum Osteocalcin within the Knee Osteoarthritis grading

Isbagio, H. (2004) · Medical Journal of Indonesia · doi:10.13181/mji.v13i2.135

Mechanisms of autoimmunity in mice lacking the mer membrane tyrosine kinase

Pl, C., Du, Y., Abraham, V., Waldman, M. T. G., Choudhury, A., Vogelgesang, A., & Wittenburg, G. (2004) · Arthritis Research · doi:10.1186/ar1369

Bone turnover markers: An appreciation of the contribution of Dr. P.D. Delmas

Eastell, R. (2008) · Bone · doi:10.1016/j.bone.2008.08.001

Arthrose : quel avenir pour les marqueurs biologiques ?

Garnero, P. (2002) · Revue du Rhumatisme · doi:10.1016/s1169-8330(02)00434-9

Osteoarthritis: degeneration of matrix or cells?

Aigner, T. G. (2004) · Arthritis Research · doi:10.1186/ar1335

SERUM CARTILAGE OLIGOMERIC MATRIX PROTEIN: A BIOMARKER FOR ACUTE ARTICULAR CARTILAGE DAMAGE

Hoch, J. M. (2012) · UKnowledge (University of Kentucky)

A critical role for leukotriene B(4 )in K/BxN serum transfer arthritis pathogenesis

Chen, M., Lam, B. K., Austen, K. F., Kanaoka, Y., & Lee, D. M. (2004) · Arthritis Research · doi:10.1186/ar1403

ALXR, a common GPCR gateway for antiinflammatory and/or proinflammatory cell activation: relevance of selective kinase and phospholipase signaling by uteroglobin, lipoxin A(4 )and serum amyloid A in ALXR-mediated chemotaxis

Antico, G., Sodin-Semrl, S., Varga, J., Miele, L., & Fiore, S. (2004) · Arthritis Research · doi:10.1186/ar1345

Clinical classification of fibromyalgia according to disease progression

Nishioka, K. (2004) · Arthritis Research · doi:10.1186/ar1410

Rheumatoid arthritis and risk factors for low bone mineral density

Arinoviche, R. (2004) · Arthritis Research · doi:10.1186/ar1424

Molecular Regulation of Gene Expression in Chondrocytes by Inflammatory Mediators

Goldring, M., Peng, H., Ijiri, K., Libermann, T. A., & Oettgen, P. (2004) · Arthritis Research · doi:10.1186/ar1382

Choroba zwyrodnieniowa stawów - problem wieloaspektowy

Koszowska, A. U., Hawranek, R., & Nowak, J. (2014)

A quantitative study of the three dimensional microstructure of articular cartilage to assess its physical integrity

Duan, X. (2012) · UWA Profiles and Research Repository (University of Western Australia)

Артросонографија и биомаркери у процени оштећења хрскавице код остеоартрозе колена

Petrović-Rackov, Q. (2009)

Physical Exercise for Osteoarthritis of the Knee

Kurosawa, H. (2011) · CRC Press eBooks · doi:10.1201/b10852-43

Estudi de la implicació dels petits proteoglicans rics en leucina i les metal·loproteases en els mecanismes patològics de l'artrosi

Monfort, J. (2013) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Relationship between Serum Hyaluronan Levels and Knee Symptoms in Osteoarthritis Patients –A Three-year Prospective Study–

Sasaki, E., 英一, 津., 祐司, 山., 前田, 周., 恭之, 石., 一平, 高., 孝, 梅., 重之, 中., 亮, 井., & 寛, 藤. (2013) · Nihon Kansetsubyou Gakkaishi/Nihon Kansetsubyo Gakkaishi · doi:10.11551/jsjd.32.441

Grape consumption improves joint flexibility and reduces pain associated with knee osteoarthritis

Tiernan, C. (2014)

Autologous Adipose Derived Adult Multipotent Stromal Cells Alter the Porcine Systemic Immune and Bone Biomarkers Response to Cancellous Bone Xenografts

Bova, J. F. (2014) · doi:10.31390/gradschool_theses.1065

Efeito do laser de baixa potência associado ou não a exercícios físicos em indivíduos com osteoartrite de joelhos: ensaio clínico cego e randomizado sobre o impacto da fisioterapia na marcha, força muscular e funcionalidade

Braghin, R. D. M. B. (2018) · doi:10.11606/t.17.2018.tde-25042018-164227

Synovial and serum levels of osteocalcin, osteoprotegerin and β-crosslaps in patients with calcium pyrophosphate deposition disease

Vele, P., Silaghi, C. N., Damian, L. O., Simon, S.-P., Craciun, A. M., & Rednic, S. (2019) · Romanian Journal of Rheumatology · doi:10.37897/rjr.2019.2.4

Bone status and aortic calcifications in chondrocalcinosis patients

Vele, P., Silaghi, C. N., Damian, L. O., Simon, S.-P., Craciun, A. M., & Rednic, S. (2020) · Revista română de medicină de laborator · doi:10.2478/rrlm-2020-0019

Hiperparatiroidismo nutricional secundario o “coquera”: ¿es el biomarcador ctx el futuro para su diagnóstico?

Ruiz, M. A. V., & Almanza, J. R. (2019) · Cultura Científica · doi:10.38017/1657463x.593

The Effects of Lower Body Positive Pressure Treadmill Running on Acute Femoral Cartilage Deformation in Healthy Males and Females

Graff, M. (2020)

Gene Dysregulation in Peripheral Blood of Young Females With Temporomandibular Joint OsteoarthritisPreprint

Kang, J. (2020) · Research Square · doi:10.21203/rs.3.rs-115380/v1

A Review on Novel Targets for Osteoarthritis Therapy

Srivastava, V., Srivastava, V., Tripathi, A. S., & Awasthi, H. (2021) · International Journal of Pharmaceutical Sciences Review and Research · doi:10.47583/ijpsrr.2021.v67i01.001

Determining the usefulness of serum hyaluronic acid levels as a predictor of progression of hand osteoarthritis: longitudinal analysis from the Iwaki cohortPreprint

Saruga, T., Sasaki, E., Inoüe, R., Chiba, D., Ota, S., Iwasaki, H., Uesato, R., Nakaji, S., & Ishibashi, Y. (2020) · doi:10.21203/rs.3.rs-16851/v1

Is the determination of bone turnover markers and vitamin D useful in the diagnosis of degeneration spine disease?

Liczner, G., Wiciński, M., Malinowski, B., & Cadelski, K. (2021) · Journal of Education Health and Sport · doi:10.12775/jehs.2021.11.09.032

Biologic Markers

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Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production

Manacu, C., Pelletier, J., Roy‐Beaudry, M., Pelletier, J.-P., Fernandes, J., Shipkolye, F. S., & Moldovan, F. (2004) · Arthritis Research · doi:10.1186/ar1385

YKL-40 as Biomarker: Focus on Cardiovascular Disease

Mygind, N. D., & Kastrup, J. (2014) · Springer eBooks · doi:10.1007/978-94-007-7740-8_11-1

دراسة تحلیلیة للمتغیرات البیوکیمیائیة للسائل الزلالی ومصل الدم کمؤشرات لإصابه مفصل الرکبة

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Особливості стану мінеральної щільности кісткової тканини у чоловіків, хворих на анкілозивний спондиліт: частота й характер порушень; вміст метаболічних показників синтезу та резорбції кісткової тканини, вітаміну D в сироватці крови; достовірні чинники по

Pavliuk, O., Marynych, L., Denyshchych, L., Kuvikova, I. P., & Shevchuk, O. V. (2023) · Lviv clinical bulletin · doi:10.25040/lkv2023.01.028

β-crosslaps in knee osteoarthritis – assessment and rehabilitation

Fugaru, O.-F., Şerbănescu, M.-S., Stefan, L. I., & Trăistaru, M. R. (2024) · Balneo and PRM Research Journal · doi:10.12680/balneo.2024.673

Serum Carboxy-terminal Cross-linking Telopeptide Fragments of Type-2 Collagen Level in the General Population: A Pilot Study

Khanna, R., Jindal, D., & Singh, S. K. (2023) · Journal of Orthopedics Traumatology and Rehabilitation · doi:10.4103/jotr.jotr_46_23

FIGURE 9 in A new frog family (Anura: Terrarana) from South America and an expanded direct-developing clade revealed by molecular phylogeny

Heinicke, M. P., Duellman, W. E., Trueb, L. M., Means, B., Ross, D., & Hedges, B. (2009) · INFM-OAR (INFN Catania) · doi:10.5281/zenodo.189882

Additional file 2 of Effects of vitamin D supplementation on liver fibrogenic factors, vitamin D receptor and liver fibrogenic microRNAs in metabolic dysfunction-associated steatotic liver disease (MASLD) patients: an exploratory randomized clinical trial

Ebrahimpour‐Koujan, S., Sohrabpour, A. A., Giovannucci, E. L., Vatannejad, A., & Esmaillzadeh, A. (2024) · Figshare · doi:10.6084/m9.figshare.25303135

Additional file 3 of Effects of vitamin D supplementation on liver fibrogenic factors, vitamin D receptor and liver fibrogenic microRNAs in metabolic dysfunction-associated steatotic liver disease (MASLD) patients: an exploratory randomized clinical trial

Ebrahimpour‐Koujan, S., Sohrabpour, A. A., Giovannucci, E. L., Vatannejad, A., & Esmaillzadeh, A. (2024) · Figshare · doi:10.6084/m9.figshare.26685855

Additional file 1 of Effects of vitamin D supplementation on liver fibrogenic factors, vitamin D receptor and liver fibrogenic microRNAs in metabolic dysfunction-associated steatotic liver disease (MASLD) patients: an exploratory randomized clinical trial

Ebrahimpour‐Koujan, S., Sohrabpour, A. A., Giovannucci, E. L., Vatannejad, A., & Esmaillzadeh, A. (2024) · Figshare · doi:10.6084/m9.figshare.25303007

Eggshell membrane supplementation improves joint symptoms and function in osteoarthritis: A randomized, double-blind, placebo-controlled trial

Yoon, H., Lee, J.-H., Park, M., Oh, M., Lee, J., & Kim, S. J. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107229

Urinary CTX-II and glucosyl-galactosyl-pyridinoline are associated with the presence and severity of radiographic knee osteoarthritis in men

Jordan, K. M., Syddall, H. E., Garnero, P., Gineyts, É., Dennison, E. M., Sayer, A. A., Delmas, P. D., Cooper, C. C., & Arden, N. K. (2005) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2005.042895 · Cited by 75

Effects of ibuprofen on molecular markers of cartilage and synovium turnover in patients with knee osteoarthritis

Gineyts, É., Mo, J. A., Ko, A., Henriksen, D. B., Curtis, S. P., Gertz, B. J., Garnero, P., & Delmas, P. D. (2004) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2003.007302 · Cited by 65

A 5-yr longitudinal study of type IIA collagen synthesis and total type II collagen degradation in patients with knee osteoarthritis--association with disease progression

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One-year increase of Coll 2-1, a new marker of type II collagen degradation, in urine is highly predictive of radiological OA progression

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Increased urinary type II collagen C-telopeptide levels in Tunisian patients with knee osteoarthritis.

Kalai, E., Bahlous, A. H. S., Charni, N., Bouzid, K., Sahli, H., Chelly, M., Meddeb, M., Zouari, B., Abdelmoula, J., & Sellami, S. (2012) · PubMed · Cited by 15