The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Prevalence of long term steroid treatment and the frequency of decision making to prevent steroid induced osteoporosis in daily clinical practice
Open accessAbstract
Background The use of oral corticosteroids (CS) is one of the most common causes of iatrogenic osteoporosis. Recently, therapeutic guidelines dealing with the skeletal complication of CS have been published.Objective To evaluate how CS are used in the community and the frequency of active intervention against corticosteroid induced osteoporosis in daily clinical practice.Material and methods After approval by the Committee on Medical Ethics and the Data Protection Commission all prescriptions for CS which were filled by pharmacies in the northeast area of Iceland (population 26,664) during a two year period were collected. Thereafter, clinical information was obtained from medical records at the healthcare centres and from the local hospital. Patients who were taking CS for at least three months a year or for repeated periods (for a total of three months annually) were included in the study. These patients also received a questionnaire about hormone replacement therapy, bisphosphonates, and dietary consumption of calcium and vitamin D.Results A total of 191 patients were included in the study or 0.7% of the population. Their mean age was 66 years (17-93) and 106/191 (55%) were women. Only 63 (33%) patients had no registered complication due to the treatment, according their medical records. Thirty nine (20%) patients had had an osteoporosis related fracture and 50 (26%) of the patients had presumed CS induced osteoporosis. A total of 52% patients were receiving supplementary vitamin D (fish liver oil) and 37% were taking calcium tablets regularly, while 91% of the patient group were consuming milk products regularly. Only 17 (9%) patients were taking bisphosphonates and 18/81 (22%) of the postmenopausal women were receiving hormone replacement therapy.Conclusions Relatively few patients receiving long term treatment with CS are also receiving primary prevention against CS induced osteoporosis, although several patients are taking vitamin D and calcium tablets. Specific treatment against osteoporosis was in most cases instituted secondary to osteoporotic complications. Thus although there are available treatment alternatives against CS induced osteoporosis, the doctors who prescribed CS did not make use of this form of treatment for their patients.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Seven in 1000 people are prescribed long-term oral corticosteroid therapy, approximately 100 times the numberwith intrinsic de fi ciency, creating a large population at risk of adrenal crisis [12].”
From Guidelines for the management of glucocorticoids during the peri‐operative period for patients with adrenal insufficiency (2020) · cites this paper as [12]
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“this chronic administration of glucocorticoids is the most common cause of secondary adrenal suppression, sometimes referred to as tertiary adrenal insuf fi ciency.”
From Guidelines for the management of glucocorticoids during the peri‐operative period for patients with adrenal insufficiency (2020) · cites this paper as [12]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Mortality after all major types of osteoporotic fracture in men and women: an observational study
Nguyen, T. V., Schneider, D. L., Sambrook, P. N., & Eisman, J. A. (1999) · The Lancet · doi:10.1016/s0140-6736(98)09075-8 · Cited by 1,926
Hench, P. S., Kendall, E. C., Slocumb, C. H., & Polley, H. F. (1949) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(24)00526-3 · Cited by 1,175
Population-Based Study of Survival after Osteoporotic Fractures
Cooper, C. C., Atkinson, E. J., Jacobsen, S. J., O’Fallon, W. M., & Melton, L. J. (1993) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a116756 · Cited by 1,100
Cushing, H. (1964) · Journal of neurosurgery · doi:10.3171/jns.1964.21.4.0318 · Cited by 849
Recommendations for the prevention and treatment of glucocorticoid‐induced osteoporosis
American College of Rheumatology task force on Osteoporosis guidelines (1996) · Arthritis & Rheumatism · doi:10.1002/art.1780391104 · Cited by 848
Glucocorticoid Therapy for Immune-Mediated Diseases: Basic and Clinical Correlates
Boumpas, D. T., Chrousos, G. P., Wilder, R. L., Cupps, T. R., & Balow, J. E. (1993) · Annals of Internal Medicine · doi:10.7326/0003-4819-119-12-199312150-00007 · Cited by 765
Kopera, H., & Ziegler, R. (1989) · Journal of Molecular Medicine · doi:10.1007/bf01719785 · Cited by 750
Intermittent Etidronate Therapy to Prevent Corticosteroid-Induced Osteoporosis
Adachi, J. D., Bensen, W., Brown, J. P., Hanley, D. A., Hodsman, A. B., Josse, R. G., Kendler, D. L., Lentle, B. C., Olszynski, W. P., Ste‐Marie, L., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199708073370603 · Cited by 683
Steroid-Induced Fractures and Bone Loss in Patients with Asthma
Adinoff, A., & Hollister, J. R. (1983) · New England Journal of Medicine · doi:10.1056/nejm198308043090502 · Cited by 662
Use of oral corticosteroids in the United Kingdom
van Staa, T. P. (2000) · QJM · doi:10.1093/qjmed/93.2.105 · Cited by 529
Research works printed but not linked: 3
- 1993, Diagnosis, prophylaxis, and treatment of osteoporosis, Am J Med, 6, 646
- Eliasson, 1998, Hormónamedferd kvenna, Íslandi (Hormone treatment of women in Iceland), Læknabladid, 84, 25
- Reid, 2000, Glucocorticosteroid-induced osteoporosis, Baillieres Clin Endocrinol Metab, 14, 279
Cited by
Sorted by citations
Waljee, A. K., Rogers, M. A. M., Lin, P., Singal, A. G., Stein, J. D., Marks, R. M., Ayanian, J. Z., & Nallamothu, B. K. (2017) · BMJ · doi:10.1136/bmj.j1415 · Cited by 830
Prevalence of oral glucocorticoid usage in the United States: a general population perspective
Overman, R. A., Yeh, J., & Deal, C. L. (2013) · Arthritis Care & Research · doi:10.1002/acr.21796 · Cited by 405
Woodcock, T., Barker, P., Daniel, S., Fletcher, S., Wass, J. A. H., Tomlinson, J. W., Misra, U., Dattani, M., Arlt, W., & Vercueil, A. (2020) · Anaesthesia · doi:10.1111/anae.14963 · Cited by 163
Glucocorticoid induced adrenal insufficiency
Prete, A., & Bancos, I. (2021) · BMJ · doi:10.1136/bmj.n1380 · Cited by 155
Cheng, X., Kinosaki, M., Takami, M., Choi, Y., Zhang, H., & Murali, R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m309690200 · Cited by 92
Metadata
- Authors
- Gudbjornsson, B., Juliusson, U. I., & Gudjonsson, F. V.
- Affiliations
- Akureyri Hospital (IS)
- Venue
- Annals of the Rheumatic Diseases
- Publisher
- Elsevier BV
- Published
- 2002-01
- Volume
- 61
- Issue
- 1
- Pages
- 32-36
- ISSN
- 0003-4967 (ISSN-L)
- OpenAlex
- W2154277972
- Semantic Scholar
- 5d9992847c802a331fb499029af82750233bdd41
- Cited by
- 152
- References
- 34
- Citations by year
- 2026: 3 · 2024: 5 · 2023: 3 · 2022: 4 · 2021: 8 · 2020: 6 · 2019: 8 · 2018: 7 · 2017: 7 · 2016: 4 · 2015: 9 · 2014: 6 · 2013: 4 · 2012: 5
- FWCI
- 9.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Annals of the Rheumatic Diseases (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed (publishedVersion)
- Hirsla (Landspítali University Hospital) (submittedVersion)
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Oncology › Bone health and treatments
- Keywords
- corticosteroid-induced osteoporosis, osteoporosis prevention, bisphosphonates, hormone replacement therapy, vitamin D supplementation, calcium supplementation, osteoporotic fractures, prescribing patterns, primary prevention
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Calcitonin, Calcium, Diphosphonates, Female, Glucocorticoids, Humans, Male, Middle Aged, Osteoporosis, Practice Patterns, Physicians', Retrospective Studies, Vitamin D, Absorptiometry, Photon, Estrogen Replacement Therapy, Fractures, Bone
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
