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Cited by 562

The DOI matches its Crossref record.

Early breakdown of the blood-retinal barrier in diabetes.

Open access
Cunha-Vaz, J., Faria de Abreu, J. R., Campos, A. J.·1975·British Journal of Ophthalmology
DOI 10.1136/bjo.59.11.649
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Abstract

The blood-retinal barrier plays an important part in the processes of retinal pathophysiology. A new clinical method for the study of the blood-retinal barrier by vitreous fluorophotometry appears to satisfy the necessary requirements in that it is quantitative and shows good reproducibility and high sensitivity. The application of this method to a series of diabetic patients with apparently "normal" fundi revealed the presence of a significant breakdown of the blood-retinal barrier in the early stages of retinal involvement in diabetes. The extent of the breakdown can be measured allowing for comparative and evolutionary evaluations. The disturbance of the blood-retinal barrier, as evidence by vitreous fluorophotometry, appears before microaneurysms or capillary closure can be demonstrated by fluorescein angiography.

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Metadata

Authors
Cunha-Vaz, J., Faria de Abreu, J. R., & Campos, A. J.
Venue
British Journal of Ophthalmology
Publisher
BMJ
Published
1975-11-01
Volume
59
Issue
11
Pages
649-656
ISSN
0007-1161 (ISSN-L)
DOI
10.1136/bjo.59.11.649
OpenAlex
W2121784482
Cited by
562
References
0
FWCI
18.35
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Early breakdown of the blood-retinal barrier in diabetes. https://app.cochat.ai/papers/10.1136/bjo.59.11.649
The paper
Cunha-Vaz, J., Faria de Abreu, J. R., & Campos, A. J. (1975). Early breakdown of the blood-retinal barrier in diabetes. British Journal of Ophthalmology. https://doi.org/10.1136/bjo.59.11.649

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.