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Clinical observations on the corneal thickness and the corneal endothelium in diabetes mellitus.
Open accessAbstract
The corneal thickness was measured by pachometry and the corneal endothelium was photographed by specular microscopy in 81 insulin-dependent juvenile diabetic outpatients. The corneal thickness of a normal group, diabetics without and with proliferative retinopathy was (mean +/- SD): 0.527 +/- 0.028, 0.544 +/- 0.028, and 0.566 +/- 0.027 mm, respectively (2p less than 0.01). As revealed in the specular photomicrographs, minute folds in the endothelial layer were found in 13 of the diabetics versus 1 of the normal group (2p less than 0.01). The cell density and the occurrence of dystrophic changes in the endothelium did not differ from those in normal persons. The augmented corneal thickness in the diabetic subjects is tentatively interpreted as minimal corneal swelling. It seemed to be present very early in the disease and may thus be one of the earliest clinically detectable changes off the diabetic eye.
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Cited by
Differences in corneal thickness and corneal endothelium related to duration in Diabetes
Lee, J. S., Oum, B. S., Choi, H. Y., Lee, J. E., & Cho, B. M. (2006) · Eye · doi:10.1038/sj.eye.6701868 · Cited by 258
Comprehensive review of the effects of diabetes on ocular health
Skarbez, K., Priestley, Y., Hoepf, M., & Koevary, S. B. (2010) · Expert Review of Ophthalmology · doi:10.1586/eop.10.44 · Cited by 117
Metadata
- Authors
- Busted, N., Olsen, T., & Schmitz, O.
- Venue
- British Journal of Ophthalmology
- Publisher
- BMJ
- Published
- 1981-10-01
- Volume
- 65
- Issue
- 10
- Pages
- 687-690
- ISSN
- 0007-1161 (ISSN-L)
- OpenAlex
- W2059027218
- Cited by
- 169
- References
- 0
- FWCI
- 0.44
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Clinical observations on the corneal thickness and the corneal endothelium in diabetes mellitus. https://app.cochat.ai/papers/10.1136/bjo.65.10.687
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- Busted, N., Olsen, T., & Schmitz, O. (1981). Clinical observations on the corneal thickness and the corneal endothelium in diabetes mellitus. British Journal of Ophthalmology. https://doi.org/10.1136/bjo.65.10.687
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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