Use of Propranolol (Inderal) in Treatment of Hypertension

Abstract

Angina of Effort-Srivastava et al.BWDIHLJOURNAL 725 obtained in the final 14 days of each 21-day period.The patients' own general assessment of each treatment is based upon the whole 21-day periods and scored on a five-point scale in the following way: -1 worsening of the angina; + 1, + 2, and +3 indicating slight, moderate, and marked improvement respectively; and 0 showing that the condition had remained unchanged when compared with that before the start of the trial.The results are summarized in Tables I and II.TABLE II.-Summarized Results and Statistical Analysis of Trial Criterion Propranolol Placebo Difference t-Value Days pain free .mean4-40 3055 0-85 ± 1-08 0-8 NS Daya ain ree range 0-14 0-14 -11-+10 No. of attacks fmean 35-5 43?3 -7-8±44 1-74 Nrange 0-300 0-350 -50-+31 0.1 P>p > 0 05 NS fmean 26-3 29-1 -28 ±5-4 0-5 NS TNT tablets .range 0-89 0-129 -41 -+ 62 r better 91 7-5 Average No. of days same 3 7 5-1 Lworse 1-3 1-5 Patients' general assessments + 1-35 + 0-75 + 0-60 ± 0 37 1-61 of angina P >0 1 NS * Based upon the following five-point scale for the full 21-day periods: Worse= -1, No change =0, Slight improvement = + 1, Moderate improvement = +2, Marked improvement = + 3. ± Figures indicate standard errors based on within-patient comparisons.NS = Not statistically significant.Values not statistically significant but near the 5 % or 10% level of significance are indicated as P > 0 05 and P > 0-1 respectively.