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Relation between extent of coronary artery disease and blood viscosity.
Open accessAbstract
Blood viscosity (shear rate 100/s) and its major determinants (packed cell volume, plasma fibrinogen concentration, and plasma viscosity) were measured before coronary angiography in 50 men aged 30-55 and related to the extent of coronary artery disease. Twenty-six men had extensive disease (stenosis of two or three major coronary vessels), and 24 had either stenosis of one vessel or no stenosis. The 26 men with extensive disease had significantly higher mean blood viscosity than those with mild or no disease and 25 healthy controls (p less than 0.001). The increased viscosity was due partly to a higher packed cell volume and partly to a higher fibrinogen concentration; plasma viscosity was not significantly increased. These differences could not be explained by smoking history. These results suggest an association between increased blood viscosity and extensive coronary artery disease in men, which merits further investigation.
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Cited by
Plasma fibrinogen and coronary risk factors: The Scottish heart health study
Lee, A. J., Smith, W. C. S., Lowe, G. D. O., & Tunstall-Pedoe, H. (1990) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(90)90075-z · Cited by 200
Self-citationFibrinogen and silent atherosclerosis in subjects with cardiovascular risk factors
Levenson, J., Giral, P., Razavian, M., Gariepy, J., & Simon, A. (1995) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.15.9.1263 · Cited by 152
Metadata
- Authors
- Lowe, G. D., Drummond, M. M., Lorimer, A. R., Hutton, I., Forbes, C. D., Prentice, C. R., & Barbenel, J. C.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1980-03-08
- Volume
- 280
- Issue
- 6215
- Pages
- 673-674
- ISSN
- 0007-1447 (ISSN-L)
- 1468-5833
- OpenAlex
- W2071760383
- Cited by
- 283
- References
- 0
- FWCI
- 14.08
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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