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Sural nerve oxygen tension in diabetes.
Open accessAbstract
Peripheral nerve oxygen tensions were assessed in vivo by using microelectrodes to measure endoneurial oxygen tension in exposed sural nerve. In 11 diabetic patients with chronic sensorimotor neuropathy the mean endoneurial oxygen tension was 39.7 (SD 10.2) mm Hg. In all but one patient compared with none of four non-neuropathic subjects the mean nerve oxygen tensions were below dorsal foot vein values. This unphysiological state may have a role in the aetiology of diabetic neuropathy.
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Citations
Cited by
Boulton, A. J. M., Malik, R. A., Arezzo, J. C., & Sosenko, J. M. (2004) · Diabetes Care · doi:10.2337/diacare.27.6.1458 · Cited by 913
Self-citationAdvances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy
Tesfaye, S., & Selvarajah, D. (2012) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2239 · Cited by 615
Pathogenesis, diagnosis and clinical management of diabetic sensorimotor peripheral neuropathy
Sloan, G., Selvarajah, D., & Tesfaye, S. (2021) · Nature Reviews Endocrinology · doi:10.1038/s41574-021-00496-z · Cited by 534
Hyperglycemia Regulates Hypoxia-Inducible Factor-1α Protein Stability and Function
Catrina, S.-B., Okamoto, K., Pereira, T., Brismar, K., & Poellinger, L. (2004) · Diabetes · doi:10.2337/diabetes.53.12.3226 · Cited by 384
Sural nerve pathology in diabetic patients with minimal but progressive neuropathy
Malik, R. A., Tesfaye, S., Newrick, P. G., Walker, D., Rajbhandari, S. M., Siddique, I., Sharma, A. K., Boulton, A. J. M., King, R. H. M., Thomas, P. K., et al. (2005) · Diabetologia · doi:10.1007/s00125-004-1663-5 · Cited by 332
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Metadata
- Authors
- Newrick, P. G., Wilson, A. J., Jakubowski, J., Boulton, A. J., & Ward, J. D.
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1986-10-25
- Volume
- 293
- Issue
- 6554
- Pages
- 1053-1054
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- OpenAlex
- W2064464513
- Cited by
- 254
- References
- 0
- FWCI
- 6.58
- Type
- journal article
- Language
- en
- Open access
- bronze
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- The paper
- Newrick, P. G., Wilson, A. J., Jakubowski, J., Boulton, A. J., & Ward, J. D. (1986). Sural nerve oxygen tension in diabetes. BMJ. https://doi.org/10.1136/bmj.293.6554.1053
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
