Does treatment for cervical intraepithelial neoplasia affect fertility and pregnancy?
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Passive smoking is easier to control (by legislation and regulation) than active addictive smoking.The public health implications of the available evidence warrant continued efforts to reduce the public's exposure to other people's tobacco smoke.
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The safety of cryotherapy on fertility and early pregnancy outcomes has been shown in older studies, albeit with low-grade quality of evidence.
“The safety of cryotherapy on fertility and early pregnancy outcomes has also been shown in older studies, albeit with low‐grade quality of evidence, contributing to its widespread use as a screen‐and‐treat approach in low‐resource settings before the advent of TA [25, 26].”
From Fertility and Miscarriage Incidence After Cervical Intraepithelial Neoplasia Treatment by Thermal Ablation: A Cohort Study (2025) · cites this paper as [26]
The Abstract (page unavailable) reports no adverse effect on subsequent pregnancy outcomes in two older cryosurgery series and says studies of treatment for cervical intraepithelial neoplasia found no effect on fertility. It does not specifically establish safety for early-pregnancy outcomes or grade the quality of the cryosurgery evidence as low. (LLM, conf=0.84)
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Wisniak, A., Yakam, V., Bolo, S. E., Moukam, A., Sormani, J., Vassilakos, P., Kenfack, B., & Petignat, P. (2025) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.17954 · Cited by 4 · see citing works
- Authors
- Hammond, R. H., & Edmonds, D. K.
- ORCID
- Hammond, R H
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 1990-12-15
- Volume
- 301
- Issue
- 6765
- Pages
- 1344-1345
- ISSN
- 0007-1447 (ISSN-L)
- 0959-8138
- 1468-5833
- OpenAlex
- W2026901451
- Cited by
- 40
- References
- 0
- Citations by year
- 2024: 2 · 2023: 2 · 2021: 1 · 2019: 1 · 2015: 4 · 2014: 1 · 2013: 1
- FWCI
- 4.48
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- BMJ (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Cervical Cancer and HPV Research
- Health Sciences › Medicine › Obstetrics and Gynecology › Endometrial and Cervical Cancer Treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Health and Contraception
- Keywords
- cervical intraepithelial neoplasia, fertility, pregnancy, treatment outcomes, tobacco smoke, passive smoking, smoking regulation
- MeSH terms
- Abortion, Spontaneous, Uterine Cervical Dysplasia, Female, Humans, Infertility, Female, Obstetric Labor Complications, Postoperative Complications, Pregnancy, Pregnancy Complications
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