Depression in pregnancy
Abstract
#### What you need to know Depression in pregnancy affects up to 10% of women, with higher rates in low and middle income countries, a rate only slightly lower than in the postpartum period.1 2 Yet, as few as 20% of pregnant women with depression receive adequate treatment.3 4 This is problematic because depression can profoundly affect a woman’s sense of wellbeing, relationships, and quality of life. Untreated or incompletely treated depression can also have adverse consequences for the offspring. Systematic reviews show an increase in markers of infant morbidity such as preterm birth, childhood emotional difficulties, behaviour problems, and, in some studies, poor cognitive development.5 6 Antenatal depression also is one of the strongest risk factors for postnatal depression, a condition linked to developmental problems in children.6 7 Severe depression can result in suicide, a major cause of maternal death.8 9 Perinatal suicides have been associated with lack of active treatment.10 Barriers to treatment include stigma, lack …
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Most women are reluctant to use antidepressant medication during pregnancy.
“Though antidepressant medication is generally considered safe by clinicians, and is being used at least in severe cases 5 , most women are reluctant to use them (Goodman, 2009;Vigod et al., 2016).”
From Internet delivered cognitive behavior therapy for antenatal depression: A randomised controlled trial (2017) · cites this paper as Vigod et al., 2016
Antenatal depression is the strongest risk factor for postpartum depression.
“AND is also the strongest risk factor for postpartum depression which is associated with several negative effects for both mother and child (Vigod et al., 2016).”
From Internet delivered cognitive behavior therapy for antenatal depression: A randomised controlled trial (2017) · cites this paper as Vigod et al., 2016
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References 89 · Cited by 148
- Authors
- Vigod, S. N., Wilson, C. A., & Howard, L. M.
- Affiliations
- University of Toronto (CA)
- King's College London (GB)
- Corresponding author
- Vigod, Simone N
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2016-03-24
- Volume
- 352
- Pages
- i1547
- ISSN
- 1756-1833 (ISSN-L)
- OpenAlex
- W2310497138
- Cited by
- 148
- References
- 89
- Citations by year
- 2026: 4 · 2025: 11 · 2024: 8 · 2023: 20 · 2022: 18 · 2021: 22 · 2020: 20 · 2019: 16 · 2018: 13 · 2017: 8 · 2016: 6 · 2015: 2
- FWCI
- 14.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- BMJ (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- National Institute for Health and Care Research (NIHR-RP-R3-12-011)
- Canadian Institutes of Health Research
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Health Professions › General Health Professions › Maternal and Neonatal Healthcare
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy-related medical research
- Keywords
- antenatal depression, postpartum depression, maternal mental health, untreated depression, maternal mortality, infant outcomes, barriers to treatment, stigma
- MeSH terms
- Antidepressive Agents, Combined Modality Therapy, Depression, Female, Humans, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Prognosis, Psychotherapy
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