The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
Preterm birth and risk of chronic kidney disease from childhood into mid-adulthood: national cohort study
Open accessAbstract
Objective: To investigate the relation between preterm birth (gestational age <37 weeks) and risk of CKD from childhood into mid-adulthood. Design: National cohort study. Setting: Sweden. Participants: 4 186 615 singleton live births in Sweden during 1973-2014. Exposures: Gestational age at birth, identified from nationwide birth records in the Swedish birth registry. Main outcome measures: CKD, identified from nationwide inpatient and outpatient diagnoses through 2015 (maximum age 43 years). Cox regression was used to examine gestational age at birth and risk of CKD while adjusting for potential confounders, and co-sibling analyses assessed the influence of unmeasured shared familial (genetic or environmental) factors. Results: 4305 (0.1%) participants had a diagnosis of CKD during 87.0 million person years of follow-up. Preterm birth and extremely preterm birth (<28 weeks) were associated with nearly twofold and threefold risks of CKD, respectively, from birth into mid-adulthood (adjusted hazard ratio 1.94, 95% confidence interval 1.74 to 2.16; P<0.001; 3.01, 1.67 to 5.45; P<0.001). An increased risk was observed even among those born at early term (37-38 weeks) (1.30, 1.20 to 1.40; P<0.001). The association between preterm birth and CKD was strongest at ages 0-9 years (5.09, 4.11 to 6.31; P<0.001), then weakened but remained increased at ages 10-19 years (1.97, 1.57 to 2.49; P<0.001) and 20-43 years (1.34, 1.15 to 1.57; P<0.001). These associations affected both males and females and did not seem to be related to shared genetic or environmental factors in families. Conclusions: Preterm and early term birth are strong risk factors for the development of CKD from childhood into mid-adulthood. People born prematurely need long term follow-up for monitoring and preventive actions to preserve renal function across the life course.
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“In another national cohort, preterm birth was associated with an increased risk of chronic kidney disease from childhood through mid-adulthood, supporting the link between reduced nephron endowment, altered renal development and later hypertension and cardiometabolic risk [111].”
From Placental Pathophysiology and Developmental Programming of Adult Cardiometabolic Risk: A Narrative Review of Pregnancy Exposures (2026) · cites this paper as [111]
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“In another national cohort, preterm birth was associated with an increased risk of chronic kidney disease from childhood through mid-adulthood, supporting the link between reduced nephron endowment, altered renal development and later hypertension and cardiometabolic risk [111].”
From Placental Pathophysiology and Developmental Programming of Adult Cardiometabolic Risk: A Narrative Review of Pregnancy Exposures (2026) · cites this paper as [111]
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Citations
Cites
Multiple Imputation for Nonresponse in Surveys
Rubin, D. B. (1987) · Wiley Series in Probability and Statistics · doi:10.1002/9780470316696 · Cited by 20,701
Epidemiology and causes of preterm birth
Goldenberg, R. L., Culhane, J. F., Iams, J. D., & Romero, R. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60074-4 · Cited by 7,801
Prevalence of chronic kidney disease in China: a cross-sectional survey
Zhang, L., Wang, F., Wang, L., Wang, W., Liu, B., Liu, J., Chen, M., He, Q., Liao, Y., Yu, X., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60033-6 · Cited by 2,104
Intrauterine growth curves based on ultrasonically estimated foetal weights
Maršál, K., Persson, P., Larsen, T., Lilja, H., Selbing, A., & Sultan, B. (1996) · Acta paediatrica · doi:10.1111/j.1651-2227.1996.tb14164.x · Cited by 1,900
Nephron Number in Patients with Primary Hypertension
Keller, G., Zimmer, G., Mall, G., Ritz, E., & Amann, K. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa020549 · Cited by 1,102
Timing of Elective Repeat Cesarean Delivery at Term and Neonatal Outcomes
Tita, A., Landon, M. B., Spong, C. Y., Lai, Y., Leveno, K. J., Varner, M. W., Moawad, A. H., Caritis, S. N., Meis, P. J., Wapner, R. J., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0803267 · Cited by 811
Jetton, J. G., Boohaker, L. J., Sethi, S. K., Wazir, S., Rohatgi, S., Soranno, D. E., Chishti, A. S., Woroniecki, R. P., Mammen, C., Swanson, J. R., et al. (2017) · The Lancet Child & Adolescent Health · doi:10.1016/s2352-4642(17)30069-x · Cited by 757
Mammen, C., Alabbas, A., Skippen, P. W., Nadel, H. R., Levine, D., Collet, J., & Matsell, D. G. (2011) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2011.10.048 · Cited by 569
Selewski, D. T., Charlton, J. R., Jetton, J. G., Guillet, R., Mhanna, M. J., Askenazi, D. J., & Kent, A. L. (2015) · PEDIATRICS · doi:10.1542/peds.2014-3819 · Cited by 568
Test for additive interaction in proportional hazards models
Li, R., & Chambless, L. (2007) · Annals of Epidemiology · doi:10.1016/j.annepidem.2006.10.009 · Cited by 548
Flagged first, then by citations
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Items 201–265 of 265
Azhibekov, T., & Bruggeman, L. A. (2025) · Cells · doi:10.3390/cells14171373 · Cited by 1
Gillen, M. C., Jackson, C. V., Selewski, D. T., Starr, M. C., & Slagle, C. L. (2026) · Pediatric Research · doi:10.1038/s41390-026-04786-y · Cited by 1
Dotis, J., Skarlatou, A., Fourikou, M., Papadopoulou, A., & Chochliourou, E. (2026) · Biomedicines · doi:10.3390/biomedicines14030517 · Cited by 1
Neonatal acute kidney injury: a survey of practices in Canadian neonatal intensive care units
Hussein, A., Ding, L., Lee, K., Mammen, C., Beltempo, M., Shah, P. S., Cheung, P., Morgan, C., Ting, J. Y., on behalf of the Canadian Neonatal Network Investigators, et al. (2026) · Journal of Perinatology · doi:10.1038/s41372-026-02635-8 · Cited by 2
Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing
Gauda, E. B., Ivanovska, J., Mascarenhas, D., Antwi, J., Mohammadi, A., & Jasani, B. (2026) · The Journal of Physiology · doi:10.1113/jp289277 · Cited by 1
The womb as the cradle of longevity: Perinatal origins of biological aging
Özdemir, Ö., & Davutoğlu, E. A. (2026) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.71328 · Cited by 2
Chronic kidney disease in pregnancy and fetomaternal outcome
Gupta, P., Chawla, I., Ara, A., & Malik, R. (2019) · International Journal of Reproduction Contraception Obstetrics and Gynecology · doi:10.18203/2320-1770.ijrcog20193769 · Cited by 1
Levin-Schwartz, Y., Curtin, P., Svensson, K., Fernandez, N. F., Kim-Schulze, S., Hair, G., Flores, D., Pantic, I., Tamayo-Ortiz, M., Pizano-Zárate, M. L., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0227219
Schuh, M. P., Griffin, R. L., Slagle, C. L., Selewski, D. T., Soranno, D. E., Kirkley, M. J., Varner, J. D., Askenazi, D. J., Menon, S., & Gist, K. M. (2025) · Kidney360 · doi:10.34067/kid.0000000824 · Cited by 1
Hedin, E., Tungsanga, S., Feng, Y., Kung, J. Y. C., Okpechi, I. G., Dart, A. B., Thompson, S., Morgan, C., Erickson, R. L., Chaturvedi, S., et al. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-090615 · Cited by 1
Cystic dysplasia of the kidneys in extremely preterm infants following acute kidney injury
Kim, S. H., Ahn, Y. H., Shin, J., Jung, Y. H., Kim, J. Y., & Choi, C. W. (2020) · Pediatric Nephrology · doi:10.1007/s00467-020-04737-7 · Cited by 1
Akutes Nierenversagen im Früh- und Neugeborenenalter
Weber, A., Zeiher, M., & Habbig, S. (2021) · Der Nephrologe · doi:10.1007/s11560-021-00555-6 · Cited by 1
Risk of Chronic Kidney Disease Higher When Born Premature
(2019) · AAP Grand Rounds · doi:10.1542/gr.42-4-45 · Cited by 1
Schiff, A. F., Deines, D., Jensen, E. T., O'Connell, N. S., Perry, C. J., Shaltout, H. A., Washburn, L. K., & South, A. M. (2023) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2023.113730 · Cited by 1
Wang, W., Li, X., Wu, X., Zhang, M., Xu, L., Li, G., & Wen, Y. (2020) · doi:10.21203/rs.3.rs-99651/v1 · Cited by 1
Panteris, E., Kakatsaki, I., Koukou, Z., Kolvatzis, C., Papanikolaou, S., & Hatzidaki, E. (2026) · Pathophysiology · doi:10.3390/pathophysiology33030067
Long-Term Risk for Chronic Kidney Disease After Premature Birth
Stapleton, F. B. (2019) · Journal watch · doi:10.1056/nejm-jw.na49056
Hasanah, K., Widajat, R. R., & Mellyana, O. (2020) · Sari Pediatri · doi:10.14238/sp22.2.2020.76-82
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Milardović, A., Čače, I. B., & Smrkulj, D. (2021) · Medicina Fluminensis · doi:10.21860/medflum2021_261183
Epidemiology and management of Chronic Kidney Disease in Children
Ku, E., & Harambat, J. (2021) · Springer eBooks · doi:10.1007/978-3-642-27843-3_127-1
Joosten, T. K. (2007) · School for International Training Digital Collections (School for International Training)
Sroka-Ostrowska, N., Pietrzak, R., Pykało-Gawińska, D., Zaręba-Szczudlik, J., Czajkowski, K., & Romejko-Wolniewicz, E. (2021) · Research Square · doi:10.21203/rs.3.rs-1137534/v1
Band, M. E. (2022) · Physician Assistant Clinics · doi:10.1016/j.cpha.2021.11.004
Cwiek, A., Suzuki, M., deRonde, K. A., Conaway, M. R., Bennett, K. M., El-Dahr, S. S., Reidy, K. J., & Charlton, J. R. (2021) · Research Square · doi:10.21203/rs.3.rs-444923/v1
Approach to pediatric renal disorders
Mann, N., & Tan, W. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-818872-9.00084-4
Relações terminológicas entre diagnósticos de enfermagem para crianças com doenças renais
da Silva, R. A. R., de Menezes, H. F., Santos, R. S. D. C., Xavier, B. L. D. Q., Dantas, J. D. C., Lopes, D. C. L., dos Santos, I. S., & dos Santos, F. R. (2022) · Revista Brasileira de Enfermagem · doi:10.1590/0034-7167-2021-0841pt
Causes and Consequences of Preterm Birth, A Systematic Review
Malik, J., Atiq, U., Naveed, M. H., Ahmad, S., Ahmad, H., & Roohi, N. (2022) · Pakistan Journal of Health Sciences · doi:10.54393/pjhs.v3i07.193
Brewer, P. L. (2022) · Digital Commons - URI (University of Rhode Island) · doi:10.23860/diss-brewer-pamela-2022
Akutes Nierenversagen und Nierenersatztherapie beim Neugeborenen
John-Kroegel, U., & Weigel, F. (2023) · Neonatologie Scan · doi:10.1055/a-1721-4607
McAleer, I. M. (2023) · Avery's Diseases of the Newborn · doi:10.1016/b978-0-323-82823-9.00074-x
Karayel, N., Sönmez, F., Girişgen, İ., Ünsal, A., Yenisey, Ç., & Önde, M. E. (2023) · Trends in Pediatrics · doi:10.59213/tp.2023.30074
Silvariño, R., Rico-Fontalvo, J. E., Villavicencio, V., Sánchez-Polo, V., & Rosa-Diez, G. J. (2024) · Nefrología Latinoamericana · doi:10.24875/nefro.m24000022
Mitterer, W., Komazec, I. O., Huber, E., Schaefer, B., Posod, A., & Kiechl-Kohlendorfer, U. (2024) · Pediatric Research · doi:10.1038/s41390-024-03210-7
World Kidney Day 2024: promoting equitable access to health care and optimal medication
Silvariño, R., Rico-Fontalvo, J. E., Villavicencio, V., Sánchez-Polo, V., & Rosa-Diez, G. J. (2024) · Nefrología Latinoamericana · doi:10.24875/nefro.m24000034
Gupta, M. P., Gupta, D., & Usman, A. (2024) · Cureus · doi:10.7759/cureus.63211
Acosta, J., Romero, M. D. C., Ayala, R., & Cueva, D. (2024) · Revista de la Sociedad Paraguaya de Nefrología. · doi:10.70108/nefrologiapy.2024.2.1.10
Pulmonary consequences of preterm birth
Albertine, K. H., & Yoder, B. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-91824-4.00009-5
Kidney Anatomy and Physiology: The Basis of Clinical Nephrology
Rayner, H. C., Thomas, M. E., Dasgupta, I., Lalayiannis, A. D., & Hameed, M. A. (2024) · Springer eBooks · doi:10.1007/978-3-031-66349-9_1
Zhang, L., Wang, X., Wu, D., Zheng, J., & Ding, F. (2025) · Kidney & Blood Pressure Research · doi:10.1159/000543714
Inage, Y., Matsumoto, K., Haruhara, K., Hirano, D., Matsui, K., Kinoshita, Y., Morimoto, K., Koda, N., Yamamoto, S., Fujimoto, T., et al. (2025) · Pediatric Research · doi:10.1038/s41390-025-04123-9
Stop using “former”: preterm birth and cardiometabolic risk to future health
Kelly, M. M. (2025) · Pediatric Research · doi:10.1038/s41390-025-04472-5
Slight acceleration in podocyte mRNA loss in preterm-born children aged 3–5 years
Cui, Z., Ning, C., Ma, J., Zhang, L., Liu, X., Kong, L., Chang, Y., & Ding, F. (2025) · Pediatric Nephrology · doi:10.1007/s00467-025-06983-z
Wu, D., Kong, L., Zhang, L., & Ding, F. (2025) · Kidney & Blood Pressure Research · doi:10.1159/000548692 · Cited by 1
A new vision for understanding pediatric kidney disease
Harita, Y. (2025) · Japanese journal of pediatric nephrology · doi:10.3165/jjpn.op.25-011
Stealing nephrons—a review on how patent ductus arteriosus physiology impacts neonatal kidney health
Condit, P. E., Harshman, L. A., Soranno, D. E., Bischoff, A. R., Harer, M. W., & McNamara, P. J. (2025) · Journal of Perinatology · doi:10.1038/s41372-025-02477-w
Li, X., Wu, X., Zhang, M., Xu, L., Li, G., Wen, Y., & Wang, W. (2021) · Figshare · doi:10.6084/m9.figshare.14759651
Li, X., Wu, X., Zhang, M., Xu, L., Li, G., Wen, Y., & Wang, W. (2021) · Figshare · doi:10.6084/m9.figshare.14759648
Wang, J., Peng, B., Wu, D., Zhang, Y., Zhang, Y., Liu, X., Wang, Y., Lin, L., & Ma, X. (2026) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.70895
Kidney health and blood pressure after very preterm birth: a cohort study at school age
Delbreil, J.-P., Leroy, V., Lorrain, S., Trigolet, M., Bonsante, F., & Iacobelli, S. (2026) · Pediatric Nephrology · doi:10.1007/s00467-026-07190-0
Philip, P., Shiri, S. K., Amirtharaj, G. J., Christudoss, P., Ponmudi, N. J., Gibikote, S., Mani, T., & Agarwal, I. (2026) · BMC Nephrology · doi:10.1186/s12882-026-04864-7
Using Pregnancy to Initiate Long-term Kidney Care for Women
Shemies, R. S., & Naicker, S. (2026) · Indian Journal of Kidney Diseases · doi:10.4103/ijkd.ijkd_4_26
Dailey, R. K., Cwiek, A., Hamil, L. C., Timberline, S. M., Kameshwar, A. K. S., Suzuki, M., Isaac, J. S., deRonde, K. A., Conaway, M. R., Bennett, K. M., et al. (2026) · Endocrinology Diabetes & Metabolism · doi:10.1002/edm2.70223
Megalin (LRP2), prenatal betamethasone, and injury susceptibility in the developing kidneyPreprint
Nakum, C., Bull, B. C., Yarlagadda, S., Indugula, S., Stowers, K., Vandenheuvel, K. A., Ference-Salo, J. T., Beamish, J. A., Volz, A., Robinson, J. E., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.02.729064
Neonatal Acute Kidney Injury—An Australian and New Zealand Perspective
Desai, S., Forbes, T. A., Carter, S. A., Kent, A. L., Prestidge, C., Selewski, D. T., Staub, E., & Raaijmakers, A. (2026) · Journal of Paediatrics and Child Health · doi:10.1111/jpc.70464
Acute kidney injury in neonates
Baptista, R. B., Grossmann, K. R., Hoogenboom, L. A., Raaijmakers, A., Selewski, D. T., Steflik, H. J., Wildes, D. M., & Starr, M. C. (2026) · Intensive Care Medicine – Paediatric and Neonatal · doi:10.1007/s44253-026-00129-1
Hypertensive disorders of pregnancy and offspring’s kidney health
Piccoli, G. B., & Longhitano, E. (2026) · Pediatric Nephrology · doi:10.1007/s00467-026-07413-4
Beyond paediatric nephrology: gaps in care for young adults
Rauchman, M., & Halabi, C. M. (2026) · Nature Reviews Nephrology · doi:10.1038/s41581-026-01110-z
CKDx – chronische Nierenerkrankung unklarer Ursache
Lovric, S., & Hoefele, J. (2026) · Die Nephrologie · doi:10.1007/s11560-026-00931-0
Wang, J., Ye, Z., Lu, Q., Chen, M., Zhao, Y., Qu, Y., & Jiang, Y. (2026) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/s41370-026-00945-9
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Patni, M. A., Nasrallah, M., Tarawneh, D. J. A., El‐Tanani, M., Ibrahim, K., Hajjo, A. M., Alali, M. M. H., Alabid, I. K., Alghoul, W. I. I., Sehrawala, S. A., et al. (2026) · Medical Sciences · doi:10.3390/medsci14050543
Ishimori, S., Ishiko, S., Fujimura, J., Yamamoto, A., Aoyama, S., Kimura, Y., Inoki, Y., Matsui, M., Horinouchi, T., Yamamura, T., et al. (2026) · Research Square · doi:10.21203/rs.3.rs-10774896/v1
Pecoraro, L., Signore, A., Dell’Anna, A., Carrino, G., Chillura, I., & Indrio, F. (2026) · Medicina · doi:10.3390/medicina62101874
Serum Growth Differentiation Factor 15 Levels in School‐Aged Children Born Preterm
Goto, M., Kobayashi, A., Kanai, H., Katsumata, N., Naito, A., & Sawanobori, E. (2026) · Acta Paediatrica · doi:10.1111/apa.70795
From prematurity and low birth weight to CKD: opportunities for intervention
Klaus, R., & Lange-Sperandio, B. (2026) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfag230
Xiong, L., Zhang, Y., Liao, Y., Zhang, Y., Mao, Y., & Xiong, T. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15207816
Metadata
- Authors
- Crump, C., Sundquist, J., Winkleby, M. A., & Sundquist, K.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- Lund University (SE)
- Stanford University (US)
- Corresponding author
- Crump, Casey
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2019-05-01
- Volume
- 365
- Pages
- l1346
- ISSN
- 1756-1833 (ISSN-L)
- 0959-8138
- PMC
- PMC6490674
- OpenAlex
- W2942751913
- Cited by
- 265
- References
- 59
- Citations by year
- 2026: 29 · 2025: 38 · 2024: 32 · 2023: 38 · 2022: 29 · 2021: 42 · 2020: 40 · 2019: 16
- FWCI
- 33.01
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- BMJ (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Lund University Publications (Lund University) (submittedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- Hjärt-Lungfonden
- Vetenskapsrådet
- National Heart, Lung, and Blood Institute (R01HL139536)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Development and Preterm Care
- Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
- Keywords
- preterm birth, chronic kidney disease, extremely preterm birth, early term birth, gestational age, childhood, midlife, risk factors, birth cohort, kidney disease prevention, long-term follow-up, Sweden, birth registry, sex differences, neonatal intensive care, neonatal sepsis
- MeSH terms
- Adolescent, Adult, Child, Child, Preschool, Female, Gestational Age, Humans, Infant, Infant, Newborn, Male, Pregnancy, Risk Factors, Sweden, Early Diagnosis, Premature Birth, Renal Insufficiency, Chronic, Young Adult
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