The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Catalogue of bias: attrition bias
Abstract
This article is part of a series of articles featuring the Catalogue of Bias introduced in this volume of BMJ Evidence-Based Medicine that describes attrition bias and outlines its potential impact on research studies and the preventive steps to minimise its risk. Attrition bias is a type of selection bias due to systematic differences between study groups in the number and the way participants are lost from a study. Differences between people who leave a study and those who continue, particularly between study groups, can be the reason for any observed effect and not the intervention itself. Associations for mortality in trials of tranexamic acid and upper gastrointestinal bleeding were no longer apparent after studies with high or unclear risk of attrition bias were removed. Over-recruitment can help prevent important attrition bias. Sampling weights and tailored replenishment samples can help to compensate for the effects of attrition bias when present.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“and/or (3) studies with high attrition rates (≥30% in at least one arm), given attrition rates of ≥30% are associated with imbalances at baseline and are therefore vulnerable to bias such as clinical and psychosocial differences between groups due to differences between those that leave or remain in the study, which is likely to have an impact on the estimated effect of the exposure.98”
Citations
Cites
Porta, M. (2026) · doi:10.1093/acref/9780197663639.001.0001 · Cited by 2,175
Sample size slippages in randomised trials: exclusions and the lost and wayward.
Schulz, K. F., & Grimes, D. A. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07882-0 · Cited by 642
Reporting attrition in randomised controlled trials
Dumville, J. C., Torgerson, D. J., & Hewitt, C. E. (2006) · BMJ · doi:10.1136/bmj.332.7547.969 · Cited by 443
Tranexamic acid for upper gastrointestinal bleeding
Bennett, C., Klingenberg, S. L., Langholz, E., & Gluud, L. L. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006640.pub3 · Cited by 188
Assessing the impact of attrition in randomized controlled trials
Hewitt, C. E., Kumaravel, B., Dumville, J. C., & Torgerson, D. J. (2010) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.01.010 · Cited by 139
Randomized controlled trial of hip protectors among women living in the community
Birks, Y., Porthouse, J., Addie, C., Loughney, K., Saxon, L., Baverstock, M., Francis, R., Reid, D., Watt, I., Torgerson, D. J., et al. (2004) · Osteoporosis International · doi:10.1007/s00198-004-1599-0 · Cited by 86
Zethof, D., Nagelhout, G. E., de Rooij, M., Driezen, P., Fong, G. T., van den Putte, B., Hummel, K., de Vries, H., Thompson, M. E., & Willemsen, M. C. (2016) · European Journal of Public Health · doi:10.1093/eurpub/ckw037 · Cited by 30
Hindmarch, P. N., Hawkins, A., McColl, E., Hayes, M., Majsak‐Newman, G., Ablewhite, J., Deave, T., Kendrick, D., & On behalf of the Keeping Children Safe study group (2015) · Trials · doi:10.1186/s13063-015-0578-4 · Cited by 26
Damen, N. L., Versteeg, H., Serruys, P. W. J. C., van Geuns, R., van Domburg, R. T., Pedersen, S. S., & Boersma, E. H. (2013) · European Journal of Preventive Cardiology · doi:10.1177/2047487313506548 · Cited by 18
Cited by
Sorted by citations
Barker, T. H., Stone, J. C., Sears, K., Klugar, M., Leonardi-Bee, J., Tufanaru, C., Aromataris, E., & Munn, Z. (2023) · JBI Evidence Synthesis · doi:10.11124/jbies-22-00125 · Cited by 471
Where to look for the most frequent biases?
Jager, K. J., Tripepi, G. L., Chesnaye, N. C., Dekker, F. W., Zoccali, C., & Stel, V. S. (2020) · Nephrology · doi:10.1111/nep.13706 · Cited by 168
Deep Learning in Breast Cancer Imaging: State of the Art and Recent Advancements in Early 2024
Carriero, A., Groenhoff, L., Vologina, E., Basile, P., & Albera, M. (2024) · Diagnostics · doi:10.3390/diagnostics14080848 · Cited by 187
Algorithmic fairness in computational medicine
Xu, J., Xiao, Y., Wang, W. H., Ning, Y., Shenkman, E. A., Bian, J., & Wang, F. (2022) · eBioMedicine · doi:10.1016/j.ebiom.2022.104250 · Cited by 170
Defining and evaluating the Hawthorne effect in primary care, a systematic review and meta-analysis
Berkhout, C., Berbra, O., Favre, J., Collins, C., Calafiore, M., Peremans, L., & Royen, P. V. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.1033486 · Cited by 174
Metadata
- Authors
- Nunan, D., Aronson, J., & Bankhead, C.
- Affiliations
- University of Oxford (GB)
- Venue
- BMJ Evidence-Based Medicine
- Publisher
- BMJ
- Published
- 2018-01-24
- Volume
- 23
- Issue
- 1
- Pages
- 21-22
- ISSN
- 1356-5524 (ISSN-L)
- 2515-446X
- 2515-4478
- OpenAlex
- W2784801669
- Cited by
- 204
- References
- 9
- Citations by year
- 2026: 25 · 2025: 36 · 2024: 32 · 2023: 27 · 2022: 39 · 2021: 24 · 2020: 15 · 2019: 6
- FWCI
- 8.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- BMJ Evidence-Based Medicine (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
- Keywords
- attrition bias, selection bias, participant dropout, trial bias, sampling weights, tranexamic acid, upper gastrointestinal bleeding, mortality
- MeSH terms
- Humans, Patient Dropouts, Bias, Selection Bias
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review