The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Unlicensed and off label drug use in neonates
Open accessAbstract
AIM: To determine the extent of use of drugs that are either not licensed (unlicensed), or are outside the terms of their product licence (off label) in a neonatal intensive care unit. METHODS: A prospective study was conducted over 13 weeks. RESULTS: 455 prescription episodes were administered to 70 babies. 63 (90%) patients were given a drug that was either unlicensed or used in an off label way. 54.7% prescription episodes were off label, many for more than one reason, and 9.9% (45) were unlicensed; 35.4% (161) prescription episodes were licensed. CONCLUSION: The use of unlicensed and off label drugs in neonatal intensive care seems to be far greater than other paediatric settings. This highlights the difficulties faced by those trying to ensure safe and effective prescribing for neonates. Urgent action is required to resolve this situation.
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Citations
Cites
Group B Streptococcal Infections
Baker, C. J. (1997) · Clinics in Perinatology · doi:10.1016/s0095-5108(18)30184-2 · Cited by 433
Unlicensed and off label drug use in paediatric wards: prospective study
Turner, S., Longworth, A., Nunn, A. J., & Choonara, I. (1998) · BMJ · doi:10.1136/bmj.316.7128.343 · Cited by 317
Self-citationUse of "off-label" and unlicensed drugs in paediatric intensive care unit
Turner, S. C. M., Gill, A. M., Nunn, T., Hewitt, B., & Choonara, I. (1996) · The Lancet · doi:10.1016/s0140-6736(96)91182-4 · Cited by 129
Self-citationPharmacokinetics and renal function in preterm infants
van den Anker, J. (1996) · Acta Paediatrica · doi:10.1111/j.1651-2227.1996.tb13942.x · Cited by 74
Cited by
A literature review on off-label drug use in children
Pandolfini, C., & Bonati, M. (2005) · European Journal of Pediatrics · doi:10.1007/s00431-005-1698-8 · Cited by 346
Metadata
- Authors
- Conroy, S., McIntyre, J., & Choonara, I.
- Venue
- Archives of Disease in Childhood - Fetal and Neonatal Edition
- Publisher
- BMJ
- Published
- 1999-03-01
- Volume
- 80
- Issue
- 2
- Pages
- F142-F145
- ISSN
- 1359-2998 (ISSN-L)
- 1468-2052
- OpenAlex
- W2115156600
- Cited by
- 286
- References
- 4
- FWCI
- 13.91
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Conroy, S., McIntyre, J., & Choonara, I. (1999). Unlicensed and off label drug use in neonates. Archives of Disease in Childhood - Fetal and Neonatal Edition. https://doi.org/10.1136/fn.80.2.f142
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
