Pectin and complications after gastric surgery: normalisation of postprandial glucose and endocrine responses.
Open accessAbstract
Pectin has been shown to minimise the fall in blood glucose seen in patients who are troubled by hypoglycaemia attacks after gastric surgery. We therefore performed 50 g glucose tolerance tests with and without 14.5 g pectin on 11 post-gastric surgery patients. After pectin, the high postprandial levels of glucose, insulin, and enteroglucagon were significantly reduced as was the fall in blood glucose between 90 and 120 minutes. These effects of pectin may reflect slower uptake of glucose from the gastrointestinal tract and provide evidence to support the use of unabsorbable carbohydrate gelling agents in treating hypoglycaemia after gastric surgery.
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A number of short-term studies involving the ingestion of up to 15 g of guar gum or pectin with each meal have demonstrated the efficacy of these dietary supplements in slowing gastric emptying, reducing GI hormone release, improving hyperglycemia and controlling dumping symptoms.
“A number of short-term studies involving the ingestion of up to 15 g of guar gum or pectin with each meal have demonstrated the efficacy of these dietary supplements in slowing gastric emptying, reducing GI hormone release, improving hyperglycemia and controlling dumping symptoms (Table 2) (48)(49)(50)(51)(52)(53)(54)(55)(56)(57).”
From Dumping syndrome after esophageal, gastric or bariatric surgery: Pathophysiology, diagnosis, and management (2017) · cites this paper as [49]
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van Beek, A. P., Emous, M., Laville, M., & Tack, J. (2017) · Obesity Reviews · doi:10.1111/obr.12467 · Cited by 288 · see citing works
- Authors
- Jenkins, D. J., Bloom, S. R., Albuquerque, R. H., Leeds, A. R., Sarson, D. L., Metz, G. L., & Alberti, K. G.
- ORCID
- Jenkins, D J
- Venue
- Gut
- Publisher
- BMJ
- Published
- 1980-07
- Volume
- 21
- Issue
- 7
- Pages
- 574-579
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- PMC
- PMC1419882
- OpenAlex
- W2123330712
- Cited by
- 48
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 1 · 2020: 1 · 2019: 1 · 2016: 1 · 2013: 1
- FWCI
- 7.11
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Gut (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- pectin, postprandial hypoglycemia, gastric surgery complications, glucose tolerance test, insulin response, enteroglucagon, postprandial blood glucose, glucose absorption
- MeSH terms
- Adult, Aged, Blood Glucose, Female, Food, Gastrectomy, Gastric Emptying, Gastrointestinal Hormones, Glucose Tolerance Test, Humans, Hypoglycemia, Insulin, Male, Middle Aged, Pectins, Postoperative Complications, Vagotomy
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