The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Food intolerance and the irritable bowel syndrome.
Open accessAbstract
Two hundred patients (156 women) with the irritable bowel syndrome were treated with dietary exclusion for three weeks. Of the 189 who completed this study, 91 (48.2%) showed symptomatic improvement. Subsequent challenge with individual foods showed that 73 of these 91 responders were able to identify one or more food intolerances and 72 remained well on a modified diet during the follow up period (mean (SD), 14.7 (7.98) months). Of the 98 patients who showed no symptomatic improvement after three weeks of strict exclusion only three were symptomatically well at follow up (mean (SD), 12.48 (8.09 months). There was no close correlation between response and symptom complex. There was a wide range of food intolerance. The majority (50%) identified two to five foods which upset them (range 1-14). The foods most commonly incriminated were dairy products (40.7%) and grains (39.4%).
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“However, so far the evidence to support widespread use of FODMAP reduction in patients with IBS is limited and comes mainly from one research group.”
From Intestinal microbiota in functional bowel disorders: a Rome foundation report (2013) · cites this paper as [258]
In the citing paper
“Reducing intake of fibre256 or FODMAPs257 is one of the simplest and safest ways of altering gut microbiota, which can lead to improvement in bloating and diarrhoea, an effect which may last for years.258”
From Intestinal microbiota in functional bowel disorders: a Rome foundation report (2013) · cites this paper as [258]
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Cites
Functional bowel disorders in apparently healthy people
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Incomplete Absorption of the Carbohydrate in All-Purpose Wheat Flour
Anderson, I. H., Levine, A. S., & Levitt, M. D. (1981) · New England Journal of Medicine · doi:10.1056/nejm198104093041507 · Cited by 378
FOOD INTOLERANCE: A MAJOR FACTOR IN THE PATHOGENESIS OF IRRITABLE BOWEL SYNDROME
Jones, V. A., Shorthouse, M., McLaughlan, P., Workman, E., & Hunter, J. O. (1982) · The Lancet · doi:10.1016/s0140-6736(82)92782-9 · Cited by 333
ORGANIC AND FUNCTIONAL DISORDERS IN 2000 GASTROENTEROLOGY OUTPATIENTS
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Learned illness behavior in patients with irritable bowel syndrome and peptic ulcer
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Svedlund, J., Ottosson, J., Sjödin, I., & Dotevall, G. (1983) · The Lancet · doi:10.1016/s0140-6736(83)90678-5 · Cited by 274
Fructose: Incomplete Intestinal Absorption in Humans
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Sorbitol intolerance: an unappreciated cause of functional gastrointestinal complaints
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Research works printed but not linked: 1
- Bently SJ, Pearson DJ, Rix KJB. Food hypersensitivity in IBS. Lancet 1983; ii: 295-6.
Cited by
Sorted by citations
Items 301–307 of 307
Synthetic Analysis of the Pathologies of the Digestive System
Guerrero, B. G., Hernández-González, I. L., Martinez, M. A. S., Vázquez, J. R., Gaitan, I. V., & Ledezma, J. C. R. (2023) · European Journal of Nutrition & Food Safety · doi:10.9734/ejnfs/2023/v15i101343
The Psychology of Irritable Bowel Syndrome
Ballou, S., & Keefer, L. (2013) · Wiley eBooks · doi:10.1002/9781394260454.ch21
Changing the culture of fluoroquinolone prescribing
(2024) · Pharmaceutical journal/The pharmaceutical journal · doi:10.1211/pj.2024.1.228064
Employee Dietary Initiative Improved Chronic Symptoms
Sudak, N. L., & Harry, M. L. (2024) · Mayo Clinic Proceedings Innovations Quality & Outcomes · doi:10.1016/j.mayocpiqo.2024.03.001
Food Intolerance – A Clinical Approach to Non-Immunologic Adverse Reactions to Food
Pratibha, M., Rajmani, Deepa, T., & Nitin, S. (2025) · Amrita Journal of Medicine · doi:10.4103/amjm.amjm_96_24
Food intolerance testing and dietary manipulation in inflammatory bowel disease
Inns, S. J. (2011) · UCL Discovery (University College London)
Swain, A., Malinao, J. A., Soutter, V., & Loblay, R. H. (2026) · Nutrients · doi:10.3390/nu18193220
Metadata
- Authors
- Nanda, R., James, R., Smith, H., Dudley, C. R., & Jewell, D. P.
- ORCID
- Nanda, R
- Venue
- Gut
- Publisher
- BMJ
- Published
- 1989-08
- Volume
- 30
- Issue
- 8
- Pages
- 1099-1104
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- PMC
- PMC1434180
- OpenAlex
- W2091843672
- Cited by
- 307
- References
- 26
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 5 · 2020: 3 · 2019: 4 · 2018: 8 · 2017: 6 · 2016: 11 · 2015: 9 · 2014: 13 · 2013: 20 · 2012: 10
- FWCI
- 10.50
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gut (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
- Keywords
- irritable bowel syndrome, food intolerance, elimination diet, food challenge, dairy products, grain, symptom improvement
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Colonic Diseases, Functional, Female, Follow-Up Studies, Food Hypersensitivity, Humans, Male, Middle Aged
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