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Cited by 422

The DOI matches its Crossref record; 90 of the 90 references it cites were found in a registry or an index.

Guidelines for the diagnosis and treatment of hepatocellular carcinoma (HCC) in adults

Open access
Ryder, S D·2003·Gut

Abstract

This document, on the diagnosis and treatment of patients with hepatocellular carcinoma (HCC), was commissioned by the British Society of Gastroenterology as part of a wider initiative to develop guidelines for clinicians in several areas of clinical practice.Cancer care has been the subject of increased scrutiny, with the development of care guidelines forming a major part of the strategy to reduce cancer related mortality in the UK.There is a strong suggestion that HCC is a disease which will be seen more frequently over the next few years, mainly as a result of the hepatitis C virus (HCV) epidemic.Previously, HCC has been a relatively rare tumour in the UK and much of the data pertaining to its diagnosis and therapy are derived from studies outside of the UK.Because of the lack of screening programmes and the fact that a significant proportion of HCC presents as symptomatic disease in individuals not known to have liver disease, most non-surgical therapies have been used in patients with advanced disease.There are a significant number of variables known to influence prognosis, with stage of underlying liver disease and tumour size at presentation being the most important.Controlling for these variables is difficult and these factors have contributed to a dearth of randomised controlled trials of treatment for this tumour.There is however a substantial amount of evidence available which can form the basis of a framework for diagnosis and management.Guidelines are not rigid protocols and they should not be construed as interfering with local clinical judgement.Hence they do not represent a directive of proscribed routes but a basis on which clinicians can consider the options available more clearly.. . . . . . . .

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Crossref · 10.1136/gut.52.suppl_3.iii1

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Metadata

Authors
Ryder, S. D.
Venue
Gut
Publisher
BMJ
Published
2003-05
Volume
52
Issue
suppl 3
Pages
iii1-iii8
ISSN
  • 0017-5749 (ISSN-L)
  • 1468-3288
OpenAlex
W2099718495
Cited by
422
References
90
FWCI
9.58
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Guidelines for the diagnosis and treatment of hepatocellular carcinoma (HCC) in adults. https://app.cochat.ai/papers/10.1136/gut.52.suppl_3.iii1
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Ryder, S. D. (2003). Guidelines for the diagnosis and treatment of hepatocellular carcinoma (HCC) in adults. Gut. https://doi.org/10.1136/gut.52.suppl_3.iii1

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.