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Randomised controlled trial of WISENSE, a real-time quality improving system for monitoring blind spots during esophagogastroduodenoscopy

Open access
Wu, Lianlian, Zhang, Jun, Zhou, Wei, An, Ping, Shen, Lei, Liu, Jun, Jiang, Xiaoda, Huang, Xu, Mu, Ganggang, Wan, Xinyue, Lv, Xiaoguang, Gao, Juan, Cui, Ning, Hu, Shan, Chen, Yiyun, Hu, Xiao, Li, Jiangjie, Chen, Di, Gong, Dexin, He, Xinqi, Ding, Qianshan, Zhu, Xiaoyun, Li, Suqin, Wei, Xiao, Li, Xia, Wang, Xuemei, Zhou, Jie, Zhang, Mengjiao, Yu, Hong Gang·2019·Gut

Abstract

Objective: Esophagogastroduodenoscopy (EGD) is the pivotal procedure in the diagnosis of upper gastrointestinal lesions. However, there are significant variations in EGD performance among endoscopists, impairing the discovery rate of gastric cancers and precursor lesions. The aim of this study was to construct a real-time quality improving system, WISENSE, to monitor blind spots, time the procedure and automatically generate photodocumentation during EGD and thus raise the quality of everyday endoscopy. Design: WISENSE system was developed using the methods of deep convolutional neural networks and deep reinforcement learning. Patients referred because of health examination, symptoms, surveillance were recruited from Renmin hospital of Wuhan University. Enrolled patients were randomly assigned to groups that underwent EGD with or without the assistance of WISENSE. The primary end point was to ascertain if there was a difference in the rate of blind spots between WISENSE-assisted group and the control group. Results: WISENSE monitored blind spots with an accuracy of 90.40% in real EGD videos. A total of 324 patients were recruited and randomised. 153 and 150 patients were analysed in the WISENSE and control group, respectively. Blind spot rate was lower in WISENSE group compared with the control (5.86% vs 22.46%, p<0.001), and the mean difference was −15.39% (95% CI −19.23 to −11.54). There was no significant adverse event. Conclusions: WISENSE significantly reduced blind spot rate of EGD procedure and could be used to improve the quality of everyday endoscopy. Trial registration number: ChiCTR1800014809; Results.

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Metadata

Authors
Wu, L., Zhang, J., Zhou, W., An, P., Shen, L., Liu, J., Jiang, X., Huang, X., Mu, G., Wan, X., Lv, X., Gao, J., Cui, N., Hu, S., Chen, Y., Hu, X., Li, J., Chen, D., Gong, D., He, X., Ding, Q., Zhu, X., Li, S., Wei, X., Li, X., Wang, X., Zhou, J., Zhang, M., & Yu, H. G.
Venue
Gut
Publisher
BMJ
Published
2019-03-11
Volume
68
Issue
12
Pages
2161-2169
ISSN
  • 0017-5749 (ISSN-L)
  • 1468-3288
OpenAlex
W2922329578
Cited by
316
References
5
FWCI
20.61
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Randomised controlled trial of WISENSE, a real-time quality improving system for monitoring blind spots during esophagogastroduodenoscopy. https://app.cochat.ai/papers/10.1136/gutjnl-2018-317366
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Wu, L., Zhang, J., Zhou, W., An, P., Shen, L., Liu, J., Jiang, X., Huang, X., Mu, G., Wan, X., Lv, X., Gao, J., Cui, N., Hu, S., Chen, Y., Hu, X., Li, J., Chen, D., Gong, D., . . . Yu, H. G. (2019). Randomised controlled trial of WISENSE, a real-time quality improving system for monitoring blind spots during esophagogastroduodenoscopy. Gut. https://doi.org/10.1136/gutjnl-2018-317366

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