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RR interval variations in young male diabetics.
Open accessAbstract
The beat-to-beat (RR interval) variation in resting heart rate was used to detect possible autonomic nerve damage in a group of 42 young asymptomatic male diabetics, employing a sensitive electrocardiographic computer technique. Compared with 25 age-matched controls, the diabetics showed both a significantly smaller mean RR interval (P less than 0.005) and less RR interval variation (P less than 0.001). Whereas only 4 of the diabetic subjects had shorter mean RR intervals, 22 (52%) of the diabetics had RR interval variations that were less than any of the normal subjects. This reduction in heart rate variation has not been previously reported in diabetics without clinical features of autonomic neuropathy and might provide a sensitive method of assessing early autonomic nerve involvement in diabetes.
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Research works printed but not linked: 4
- Campbell, I. W., McGarry, S., Smith, D. N., Neilson, J. M., and Clarke, B. F. 1975. Continuous electrocardiographic recording during exercise in young male diabetics. A computer study. British Heart Journal, 37, 277. · DOI
- Master, A. M., and Rosenfeld, I. 1961. Criteria for the clinical application of the 'two-step' exercise test: observations of false-negative and false-positive responses. Journal of the American Medical Association, 178, 283. · doi:10.1001/jama.1961.03040420023006
- Rose, G. A., and Blackburn, H. (1968). Cardiovascular Survey Methods. World Health Organization, Geneva.
- Wheeler, T., and Watkins, P. J. (1973). Cardiac denervation in diabetes. British Medical Journal, 4, 584. · DOI · Paper page
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Metadata
- Authors
- Murray, A., Ewing, D. J., Campbell, I. W., Neilson, J. M., & Clarke, B. F.
- Venue
- Heart
- Publisher
- BMJ
- Published
- 1975-08-01
- Volume
- 37
- Issue
- 8
- Pages
- 882-885
- ISSN
- 1355-6037 (ISSN-L)
- OpenAlex
- W2059479870
- Cited by
- 177
- References
- 0
- FWCI
- 4.87
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Murray, A., Ewing, D. J., Campbell, I. W., Neilson, J. M., & Clarke, B. F. (1975). RR interval variations in young male diabetics. Heart. https://doi.org/10.1136/hrt.37.8.882
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