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Cited by 177

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RR interval variations in young male diabetics.

Open access
Murray, A, Ewing, D J, Campbell, I W, Neilson, J M, Clarke, B F·1975·Heart

Abstract

The beat-to-beat (RR interval) variation in resting heart rate was used to detect possible autonomic nerve damage in a group of 42 young asymptomatic male diabetics, employing a sensitive electrocardiographic computer technique. Compared with 25 age-matched controls, the diabetics showed both a significantly smaller mean RR interval (P less than 0.005) and less RR interval variation (P less than 0.001). Whereas only 4 of the diabetic subjects had shorter mean RR intervals, 22 (52%) of the diabetics had RR interval variations that were less than any of the normal subjects. This reduction in heart rate variation has not been previously reported in diabetics without clinical features of autonomic neuropathy and might provide a sensitive method of assessing early autonomic nerve involvement in diabetes.

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Research works printed but not linked: 4

  1. Campbell, I. W., McGarry, S., Smith, D. N., Neilson, J. M., and Clarke, B. F. 1975. Continuous electrocardiographic recording during exercise in young male diabetics. A computer study. British Heart Journal, 37, 277. · DOI
  2. Master, A. M., and Rosenfeld, I. 1961. Criteria for the clinical application of the 'two-step' exercise test: observations of false-negative and false-positive responses. Journal of the American Medical Association, 178, 283. · doi:10.1001/jama.1961.03040420023006
  3. Rose, G. A., and Blackburn, H. (1968). Cardiovascular Survey Methods. World Health Organization, Geneva.
  4. Wheeler, T., and Watkins, P. J. (1973). Cardiac denervation in diabetes. British Medical Journal, 4, 584. · DOI · Paper page

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Metadata

Authors
Murray, A., Ewing, D. J., Campbell, I. W., Neilson, J. M., & Clarke, B. F.
Venue
Heart
Publisher
BMJ
Published
1975-08-01
Volume
37
Issue
8
Pages
882-885
ISSN
1355-6037 (ISSN-L)
OpenAlex
W2059479870
Cited by
177
References
0
FWCI
4.87
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: RR interval variations in young male diabetics. https://app.cochat.ai/papers/10.1136/hrt.37.8.882
The paper
Murray, A., Ewing, D. J., Campbell, I. W., Neilson, J. M., & Clarke, B. F. (1975). RR interval variations in young male diabetics. Heart. https://doi.org/10.1136/hrt.37.8.882

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.