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Prolonged QT period in diabetic autonomic neuropathy: a possible role in sudden cardiac death?
Open accessAbstract
Twenty four men with insulin dependent diabetes and different degrees of autonomic neuropathy were studied to establish the response of the QT interval to various heart rates. Nine men with autonomic neuropathy had a longer QT interval than 13 healthy individuals and 15 patients who had diabetes without, or with only mild, autonomic neuropathy. Those with autonomic neuropathy also had a proportionally greater lengthening of the QT interval for a given increase in RR interval. The results of this study suggest a basis for the finding that sudden death is more common in patients with diabetic autonomic neuropathy.
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Citations
Cited by
Vinik, A. I., Maser, R. E., Mitchell, B. D., & Freeman, R. (2003) · Diabetes Care · doi:10.2337/diacare.26.5.1553 · Cited by 2,044
Composite Autonomic Scoring Scale for Laboratory Quantification of Generalized Autonomic Failure
Low, P. A. (1993) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(12)60631-4 · Cited by 465
Acute myocardial infarction in the diabetic patient: Pathophysiology, clinical course and prognosis
Jacoby, R. M., & Nesto, R. W. (1992) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(92)90033-j · Cited by 349
Mortality in Diabetic Patients with Cardiovascular Autonomic Neuropathy
Rathmann, W., Ziegler, D., Jahnke, M., Haastert, B., & Cries, F. A. (1993) · Diabetic Medicine · doi:10.1111/j.1464-5491.1993.tb00173.x · Cited by 274
VEGLIO, M., BRUNO, G., BORRA, M., MACCHIA, G., BARGERO, G., D'ERRICO, N., PAGANO, G. F., & CAVALLO‐PERIN, P. (2002) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2002.00955.x · Cited by 132
Metadata
- Authors
- Bellavere, F., Ferri, M., Guarini, L., Bax, G., Piccoli, A., Cardone, C., & Fedele, D.
- Venue
- Heart
- Publisher
- BMJ
- Published
- 1988-03-01
- Volume
- 59
- Issue
- 3
- Pages
- 379-383
- ISSN
- 1355-6037 (ISSN-L)
- OpenAlex
- W2126580636
- Cited by
- 182
- References
- 0
- FWCI
- 3.22
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Bellavere, F., Ferri, M., Guarini, L., Bax, G., Piccoli, A., Cardone, C., & Fedele, D. (1988). Prolonged QT period in diabetic autonomic neuropathy: a possible role in sudden cardiac death? Heart. https://doi.org/10.1136/hrt.59.3.379
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
