A new algorithm for reducing the workload of experts in performing systematic reviews
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OBJECTIVE: To determine whether a factorized version of the complement naïve Bayes (FCNB) classifier can reduce the time spent by experts reviewing journal articles for inclusion in systematic reviews of drug class efficacy for disease treatment. DESIGN: The proposed classifier was evaluated on a test collection built from 15 systematic drug class reviews used in previous work. The FCNB classifier was constructed to classify each article as containing high-quality, drug class-specific evidence or not. Weight engineering (WE) techniques were added to reduce underestimation for Medical Subject Headings (MeSH)-based and Publication Type (PubType)-based features. Cross-validation experiments were performed to evaluate the classifier's parameters and performance. MEASUREMENTS: Work saved over sampling (WSS) at no less than a 95% recall was used as the main measure of performance. RESULTS: The minimum workload reduction for a systematic review for one topic, achieved with a FCNB/WE classifier, was 8.5%; the maximum was 62.2% and the average over the 15 topics was 33.5%. This is 15.0% higher than the average workload reduction obtained using a voting perceptron-based automated citation classification system. CONCLUSION: The FCNB/WE classifier is simple, easy to implement, and produces significantly better results in reducing the workload than previously achieved. The results support it being a useful algorithm for machine-learning-based automation of systematic reviews of drug class efficacy for disease treatment.
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Another text mining algorithm achieved workload savings ranging from 8.5 to 62% with 15 test datasets, similar to our findings with Abstrackr (9 to 80%), but their results were based on a threshold of a minimum 95% recall of relevant studies, which is too low for systematic reviews.
“Whilst another text mining algorithm [17] achieved workload savings ranging from 8.5 to 62 % with 15 test datasets, which are similar to our findings with Abstrackr (9 to 80 %), their results were based on a threshold of a minimum 95 % recall of relevant studies, which is too low for systematic reviews.”
From Faster title and abstract screening? Evaluating Abstrackr, a semi-automated online screening program for systematic reviewers (2015) · cites this paper as [17]
This study and others that have evaluated semi-automated screening with support vector models, semantic vector models, and complement naïve Bayes models indicate that considerable workload savings can be achieved.
“This study and others that have evaluated semi-automated screening with support vector models [14, 15], semantic vector models [16], and complement naïve Bayes models [17] indicate that considerable workload savings can be achieved.”
From Faster title and abstract screening? Evaluating Abstrackr, a semi-automated online screening program for systematic reviewers (2015) · cites this paper as [17]
Cites
Evidence based medicine: what it is and what it isn't
Sackett, D. L., Rosenberg, W. M. C., Gray, J. A. M., Haynes, R. B., & Richardson, W. S. (1996) · BMJ · doi:10.1136/bmj.312.7023.71 · Cited by 15,769 · see citing works
Reducing Workload in Systematic Review Preparation Using Automated Citation Classification
Cohen, A. M., Hersh, W. R., Peterson, K., & Yen, P.-Y. (2006) · Journal of the American Medical Informatics Association · doi:10.1197/jamia.m1929 · Cited by 411 · see citing works
Text Categorization Models for High-Quality Article Retrieval in Internal Medicine
Aphinyanaphongs, Y. (2004) · Journal of the American Medical Informatics Association · doi:10.1197/jamia.m1641 · Cited by 177 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
O’Mara-Eves, A., Thomas, J., McNaught, J., Miwa, M., & Ananiadou, S. (2015) · Systematic Reviews · doi:10.1186/2046-4053-4-5 · Cited by 681 · see citing works
Rathbone, J., Hoffmann, T., & Glasziou, P. (2015) · Systematic Reviews · doi:10.1186/s13643-015-0067-6 · Cited by 184 · see citing works
“…for evaluation in preference to other text mining tools because existing literature indicates that the recall accuracy of Abstrackr is very high [14 – 17], and therefore, a promising predictive text mining tool for systematic reviews, where the primary goal is to identify all relevant studies.”
BackgroundResultInfluentialHoward, B. E., Phillips, J., Tandon, A., Maharana, A., Elmore, R., Mav, D., Sedykh, A., Thayer, K., Merrick, B. A., Walker, V., et al. (2020) · Environment International · doi:10.1016/j.envint.2020.105623 · Cited by 157 · see citing works
“…examples of research from this category, including our own recent work (Cohen, 2006; Cohen et al., 2006; Martinez et al., 2008; Cohen et al., 2010; Matwin et al., 2010; Wallace et al., 2010a, 2010b; Cohen, 2011; Wallace and Small, 2011; Kim and Choi, 2012; Jonnalagadda and Petitti, 2013; Miwa et…”
MethodPrioritising references for systematic reviews with RobotAnalyst: A user study
Przybyła, P., Brockmeier, A. J., Kontonatsios, G., Le Pogam, M., McNaught, J., von Elm, E., Nolan, K., & Ananiadou, S. (2018) · Research Synthesis Methods · doi:10.1002/jrsm.1311 · Cited by 148 · see citing works
Khabsa, M., Elmagarmid, A., Ilyas, I., Hammady, H., & Ouzzani, M. (2016) · Machine Learning · doi:10.1007/s10994-015-5535-7 · Cited by 98 · see citing works
Cohen, A. M., Smalheiser, N. R., McDonagh, M. S., Yu, C., Adams, C. E., Davis, J. M., & Yu, P. S. (2015) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocu025 · Cited by 78 · see citing works
Screening articles for systematic reviews with ChatGPT
Syriani, E., David, I., & Kumar, G. (2024) · Journal of Computer Languages · doi:10.1016/j.cola.2024.101287 · Cited by 82 · see citing works
Screening nonrandomized studies for medical systematic reviews: a comparative study of classifiers
Bekhuis, T., & Demner-Fushman, D. (2012) · Artificial Intelligence in Medicine · doi:10.1016/j.artmed.2012.05.002 · Cited by 70 · see citing works
Improving reference prioritisation with PICO recognition.
Brockmeier, A. J., Ju, M., Przybyła, P., & Ananiadou, S. (2019) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-019-0992-8 · Cited by 62 · see citing works
Machine learning to assist risk-of-bias assessments in systematic reviews
Millard, L. A., Flach, P. A., & Higgins, J. P. (2016) · International Journal of Epidemiology · doi:10.1093/ije/dyv306 · Cited by 65 · see citing works
Text mining to support abstract screening for knowledge syntheses: a semi-automated workflow
Pham, B., Jovanovic, J., Bagheri, E., Antony, J., Ashoor, H., Nguyen, T. T., Rios, P., Robson, R., Thomas, S. M., Watt, J., et al. (2021) · Systematic Reviews · doi:10.1186/s13643-021-01700-x · Cited by 63 · see citing works
A new iterative method to reduce workload in systematic review process
Jonnalagadda, S., & Petitti, D. (2013) · International Journal of Computational Biology and Drug Design · doi:10.1504/ijcbdd.2013.052198 · Cited by 61 · see citing works
Toward good in vitro reporting standards
Hartung, T. (2019) · ALTEX · doi:10.14573/altex.1812191 · Cited by 63 · see citing works
“, 2016), SysRev15, DistillerSR (Matwin et al., 2010), and other software applications are in the process of developing various”
BackgroundMethodOlorisade, B. K., Brereton, P., & Andras, P. (2017) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2017.07.010 · Cited by 54 · see citing works
Olorisade, B. K., de Quincey, E., Brereton, P., & Andras, P. (2016) · Proceedings of the 20th International Conference on Evaluation and Assessment in Software Engineering · doi:10.1145/2915970.2915982 · Cited by 42 · see citing works
An SVM-based high-quality article classifier for systematic reviews
Kim, S., & Choi, J. (2014) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2013.10.005 · Cited by 39 · see citing works
Advanced analytics for the automation of medical systematic reviews
Timsina, P., Liu, J., & El-Gayar, O. (2016) · Information Systems Frontiers · doi:10.1007/s10796-015-9589-7 · Cited by 33 · see citing works
Automatic endpoint detection to support the systematic review process.
Blake, C., & Lucic, A. (2015) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2015.05.004 · Cited by 22 · see citing works
- Authors
- Matwin, S., Kouznetsov, A., Inkpen, D., Frunza, O., & O'Blenis, P.
- Affiliations
- University of Ottawa (CA)
- University of New Brunswick (CA)
- Corresponding author
- Kouznetsov, Alexandre
- Venue
- Journal of the American Medical Informatics Association
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-07
- Volume
- 17
- Issue
- 4
- Pages
- 446-453
- ISSN
- 1067-5027 (ISSN-L)
- 1527-974X
- PMC
- PMC2995653
- OpenAlex
- W2154352790
- Cited by
- 100
- References
- 3
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 8 · 2023: 13 · 2022: 2 · 2021: 6 · 2020: 8 · 2019: 4 · 2018: 4 · 2017: 8 · 2016: 3 · 2015: 16 · 2014: 5 · 2013: 5 · 2012: 7
- FWCI
- 1.50
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- public-domain
- Locations
- Journal of the American Medical Informatics Association (publishedVersion, public-domain)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ontario Centres of Excellence
- Natural Sciences and Engineering Research Council of Canada
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Physical Sciences › Computer Science › Artificial Intelligence › Text and Document Classification Technologies
- Physical Sciences › Computer Science › Information Systems › Information Retrieval and Search Behavior
- Keywords
- systematic reviews, citation classification, Medical Subject Headings
- MeSH terms
- Algorithms, Automation, Bayes Theorem, Decision Support Techniques, Drug Therapy, Efficiency, Humans, Review Literature as Topic, Information Storage and Retrieval, Evidence-Based Medicine
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