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A fluorimetric and enzymatic method for the estimation of serum total bile acids
Open accessAbstract
The enzymatic technique using 3α-hydroxysteroid dehydrogenase for determining bile acids in blood has been modified by measuring the reduced nicotinamide adenine dinucleotide fluorimetrically. The increased sensitivity attained enables the concentration of total bile acids in serum to be estimated using 3 ml for normal subjects and 1 ml for jaundiced patients. The range of normal values in serum was found to be 0-4·7 μmol/litre for males and 1·0-8·2 μmol/litre for females.
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Cited by
A simple and sensitive assay of total serum bile acids
Mashige, F., Imai, K., & Osuga, T. (1976) · Clinica Chimica Acta · doi:10.1016/0009-8981(76)90007-3 · Cited by 329
Claudel, T., Sturm, E., Duez, H., Torra, I. P., Sirvent, A., Kosykh, V., Fruchart, J.-C., Dallongeville, J., Hum, D. W., Kuipers, F., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci14505 · Cited by 286
Claudel, T., Sturm, E., Duez, H., Torra, I. P., Sirvent, A., Kosykh, V., Fruchart, J.-C., Dallongeville, J., Hum, D. W., Kuipers, F., et al. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0214505 · Cited by 279
Jonkers, I. J. A. M., Smelt, A. H. M., Ledeboer, M., Hollum, M. E., Biemond, I., Kuipers, F., Stellaard, F., Boverhof, R., Meinders, A. E., Lamers, C. H. B. W., et al. (2003) · Gut · doi:10.1136/gut.52.1.109 · Cited by 54
Metadata
- Authors
- Murphy, G. M., Billing, B. H., & Baron, D. N.
- Venue
- Journal of Clinical Pathology
- Publisher
- BMJ
- Published
- 1970-10
- Volume
- 23
- Issue
- 7
- Pages
- 594-598
- ISSN
- 0021-9746 (ISSN-L)
- 1472-4146
- OpenAlex
- W2134075987
- Cited by
- 238
- References
- 0
- FWCI
- 12.30
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: A fluorimetric and enzymatic method for the estimation of serum total bile acids. https://app.cochat.ai/papers/10.1136/jcp.23.7.594
- The paper
- Murphy, G. M., Billing, B. H., & Baron, D. N. (1970). A fluorimetric and enzymatic method for the estimation of serum total bile acids. Journal of Clinical Pathology. https://doi.org/10.1136/jcp.23.7.594
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
