Cited by 113Smoking Behavior and CessationAcute Myocardial Infarction ResearchCardiac Health and Mental Health

The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.

Smoking reduction, smoking cessation, and incidence of fatal and non-fatal myocardial infarction in Denmark 1976–1998: a pooled cohort study

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Godtfredsen, N S, Osler, M, Vestbo, J, Andersen, I, Prescott, E·2003·Journal of Epidemiology and Community Health

Abstract

OBJECTIVE: To analyse the effects of smoking reduction and smoking cessation on incidence of myocardial infarction after adjustment for established cardiovascular risk factors. DESIGN: Prospective cohort study with record linkage to mortality and hospital registers. The association of individual change in smoking with myocardial infarction was examined in Cox proportional hazard analyses with continuous heavy smokers (> or =5 cigarettes/day) as reference. SETTING: Pooled data from three population studies conducted in Copenhagen, Denmark. PARTICIPANTS: 10 956 men and 8467 women with complete information on smoking habits at two examinations five to ten years apart were followed up from the second examination for a first hospital admission or death from myocardial infarction. Mean duration of follow up was 13.8 years. MAIN RESULTS: A total of 643 participants who were heavy smokers at baseline reduced their daily tobacco consumption by at least 50% without quitting between first and second examination, and 1379 participants stopped smoking. During follow up 1658 men and 521 women experienced a fatal or non-fatal myocardial infarction. After adjustment for cardiovascular risk factors, people who stopped smoking had a decreased risk of myocardial infarction, hazard ratio 0.71 (95% confidence intervals 0.59 to 0.85). Smoking reduction was not associated with reduced risk of myocardial infarction, hazard ratio 1.15 (95% confidence intervals 0.94 to 1.40). These associations remained unchanged after controlling for baseline illness in different ways. CONCLUSIONS: Smoking cessation in healthy people reduces the risk of a subsequent myocardial infarction, whereas this study provides no evidence of benefit from reduction in the amount smoked.

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Research works printed but not linked: 5

  1. 1998, Eur Heart J, 19, A12
  2. 1981, Scand J Soc Med, suppl 20, 5
  3. 1989, Scand J Soc Med, 170, 1
  4. 2001, Nicotine Tobacco Research, 3, 249, 10.1080/14622200124191 · DOI
  5. 1999, J Cardiovasc Risk, 6, 287

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Metadata

Authors
Godtfredsen, N. S., Osler, M., Vestbo, J., Andersen, I., & Prescott, E.
Affiliations
  • Copenhagen University Hospital (DK)
  • University of Copenhagen (DK)
  • Hvidovre Hospital (DK)
Corresponding author
Godtfredsen, N S
Venue
Journal of Epidemiology and Community Health
Publisher
BMJ
Published
2003-06
Volume
57
Issue
6
Pages
412-416
ISSN
  • 0141-7681 (ISSN-L)
  • 0143-005X
  • 1470-2738
OpenAlex
W2010564219
Cited by
112
References
31
Citations by year
2026: 2 · 2025: 2 · 2024: 1 · 2023: 3 · 2022: 2 · 2021: 6 · 2020: 3 · 2018: 8 · 2017: 5 · 2016: 1 · 2015: 1 · 2014: 5 · 2013: 8 · 2012: 8
FWCI
4.99
Type
journal article
Language
en
Open access
Locations
  • Journal of Epidemiology & Community Health (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Keywords
smoking cessation, smoking reduction, myocardial infarction, cardiovascular risk factors, heavy smokers, tobacco use, Denmark
MeSH terms
Cause of Death, Denmark, Female, Humans, Male, Middle Aged, Myocardial Infarction, Prospective Studies, Risk Factors, Smoking, Cohort Studies, Incidence, Proportional Hazards Models, Smoking Cessation

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