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A method for estimating the number of motor units in thenar muscles and the changes in motor unit count with ageing
Open accessAbstract
A method for estimating the number of motor units in median innervated thenar muscles is described. In normal human subjects under 40 years of age, the mean and 1 SD was 253+34. The number of motor units falls with increasing age, especially after mid life, so that elderly subjects often have less than one-half the number in youth despite good strength. The cause is not known but probably includes peripheral nerve trauma and `primary neuronal cell death'.
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Citations
Cited by
Janssen, I., Heymsfield, S. B., & Ross, R. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50216.x · Cited by 3,139
Proske, U., & Gandevia, S. C. (2012) · Physiological Reviews · doi:10.1152/physrev.00048.2011 · Cited by 2,223
Invited Review: Aging and sarcopenia
Doherty, T. J. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00347.2003 · Cited by 1,764
Mitchell, W. K., Williams, J., Atherton, P., Larvin, M., Lund, J., & Narici, M. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00260 · Cited by 1,377
Sarcopenia: characteristics, mechanisms and functional significance
Narici, M. V., & Maffulli, N. (2010) · British Medical Bulletin · doi:10.1093/bmb/ldq008 · Cited by 827
Metadata
- Authors
- Brown, W. F.
- Venue
- Journal of Neurology, Neurosurgery & Psychiatry
- Publisher
- BMJ
- Published
- 1972-12-01
- Volume
- 35
- Issue
- 6
- Pages
- 845-852
- ISSN
- 0022-3050 (ISSN-L)
- OpenAlex
- W2132905212
- Cited by
- 279
- References
- 0
- FWCI
- 12.98
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: A method for estimating the number of motor units in thenar muscles and the changes in motor unit count with ageing. https://app.cochat.ai/papers/10.1136/jnnp.35.6.845
- The paper
- Brown, W. F. (1972). A method for estimating the number of motor units in thenar muscles and the changes in motor unit count with ageing. Journal of Neurology, Neurosurgery & Psychiatry. https://doi.org/10.1136/jnnp.35.6.845
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
