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Painful peripheral states and sympathetic blocks.
Open accessAbstract
In various chronic painful states, the sympathetic nerve supply was blocked either by injecting the sympathetic chain and ganglia with local anaesthesia or by the injection of guanethidine during occlusion of the circulation. There was a striking relation between the presence of hyperpathia and the relief of pain by the blocks. The sympathetic block was unlikely to relieve the pain unless hyperpathia accompanied the pain; when hyperpathia was present, a sympathetic block relieved both the constant pain and the hyperpathia. The effectiveness of the guanethidine blocks shows that the pain and the hyperpathia are maintained by the emission of noradrenaline in the periphery. The facts related to the sympathetic system and sensibility are discussed.
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Citations
Cited by
Ho Kim, S., & Mo Chung, J. (1992) · Pain · doi:10.1016/0304-3959(92)90041-9 · Cited by 3,069
Seltzer, Z., Dubner, R., & Shir, Y. (1990) · Pain · doi:10.1016/0304-3959(90)91074-s · Cited by 1,847
The natural history of acute painful neuropathy in diabetes mellitus.
Archer, A. G., Watkins, P. J., Thomas, P. K., Sharma, A. K., & Payan, J. (1983) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.46.6.491 · Cited by 342
Similarities between severe tinnitus and chronic pain
Moller, A. R. (2000) · Journal of the American Academy of Audiology · doi:10.1055/s-0042-1748038 · Cited by 240
Metadata
- Authors
- Loh, L., & Nathan, P. W.
- Venue
- Journal of Neurology, Neurosurgery & Psychiatry
- Publisher
- BMJ
- Published
- 1978-07-01
- Volume
- 41
- Issue
- 7
- Pages
- 664-671
- ISSN
- 0022-3050 (ISSN-L)
- OpenAlex
- W2117422968
- Cited by
- 275
- References
- 0
- FWCI
- 7.75
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Painful peripheral states and sympathetic blocks. https://app.cochat.ai/papers/10.1136/jnnp.41.7.664
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- Loh, L., & Nathan, P. W. (1978). Painful peripheral states and sympathetic blocks. Journal of Neurology, Neurosurgery & Psychiatry. https://doi.org/10.1136/jnnp.41.7.664
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
