Latency of the Achilles tendon reflex for detection of reduced functions of the peripheral nervous system in workers exposed to lead.
Open accessAbstract
The latency of the soleus muscle potential, evoked by a tap of the Achilles tendon, was used in the mass assessment of healthy male workers exposed to lead. Three groups were studied: a control, a low exposure, and a high exposure group. Mean blood lead concentrations were 9.3, 19.2, and 53.1 micrograms/100 ml respectively. Latencies were adjusted for age and height and then compared among the three groups. The mean corrected latency of the high exposure group showed a 4% increase compared with the other two groups (p < 0.01). The latencies of the other two groups showed no between group differences. These results were consistent with previous neurophysiological studies done by many researchers on workers exposed to lead. They suggested that nerve conduction velocities decreased from 3 to 13% among workers whose mean blood lead concentrations were more than 30 micrograms/100 ml. The method was simple, time conserving, non-invasive, and non-aversive, and provided a quantitative measure of the nerve conduction velocities of peripheral nerves. Thus it may be useful for early detection of occupationally related impairment of peripheral nerves.
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Conduction time or velocity along the peripheral nerve, particularly the proximal segment, is evaluated by obtaining measurements of tendon reflex latency.
“The conduction time or velocity along the peripheral nerve, particularly the proximal segment, is evaluated by obtaining measurements of tendon reflex latency 11,12,19 .”
From Motion Analysis of Normal Patellar Tendon Reflex (2013) · cites this paper as [12]
The Abstract describes tendon-reflex latency as a way to quantify nerve conduction time, and the Results say the method includes proximal as well as distal conduction. But the Results also state that it is not a specific measure of nerve conduction velocity and cannot pinpoint which portion accounts for a change in latency; the claim overstates its ability to evaluate the proximal segment in particular. (LLM, conf=0.84)
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Frijns, C. J. M., Laman, D. M., van Duijn, M. A. J., & van Duijn, H. (1997) · Clinical Neurology and Neurosurgery · doi:10.1016/s0303-8467(96)00593-8 · Cited by 78 · see citing works
Electrophysiological recording of deep tendon reflexes: normative data in children and in adults
Péréon, Y., Nguyen The Tich, S., Fournier, E., Genet, R., & Guihéneuc, P. (2004) · Neurophysiologie Clinique/Clinical Neurophysiology · doi:10.1016/j.neucli.2004.04.005 · Cited by 35 · see citing works
Motion Analysis of Normal Patellar Tendon Reflex
Tham, L. K., Osman, N. A. A., Abas, W. A. B. W., & Lim, K. S. (2013) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100015985 · Cited by 4 · see citing works
- Authors
- Ogawa, Y., Hirata, M., Okayama, A., Ichikawa, Y. E., & Goto, S.
- Affiliations
- Jikei University School of Medicine (JP)
- ORCID
- Venue
- Occupational and Environmental Medicine
- Publisher
- BMJ
- Published
- 1993-03-01
- Volume
- 50
- Issue
- 3
- Pages
- 229-233
- ISSN
- 0007-1072 (ISSN-L)
- 1351-0711
- PMC
- PMC1061269
- OpenAlex
- W2060009724
- Cited by
- 7
- References
- 0
- Citations by year
- 2016: 1 · 2013: 1
- FWCI
- 0.42
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Occupational and Environmental Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Heavy Metal Exposure and Toxicity
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Peripheral Nerve Disorders
- Health Sciences › Medicine › Neurology › Peripheral Neuropathies and Disorders
- Keywords
- lead exposure, Achilles tendon reflex, nerve conduction latency, peripheral nerve function, blood lead levels, occupational neurotoxicity
- MeSH terms
- Achilles Tendon, Adult, Age Factors, Body Height, Evoked Potentials, Humans, Lead Poisoning, Male, Metallurgy, Middle Aged, Occupational Diseases, Peripheral Nerves, Reaction Time, Reflex, Skin Temperature
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