Marburg virus disease
Open accessAbstract
Summary: In the late summer of 1967 an epidemic in thirty-one patients in Germany and Yugoslavia of a disease transmitted from African green monkeys occurred; seven patients died. The incubation period was from 4 to 7 days. The main clinical features were headache, high fever, diarrhoea, a very characteristic rash, severe bleeding tendency and involvement of the central nervous system. Nearly all organs were involved and showed severe cell necroses. The aetiological agent was identified as an RNS-virus and was named Marburg virus. It was detected in the blood, urine, throat-washing and seminal fluid.
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Marburg virus disease outbreaks, mathematical models, and disease parameters: a systematic review
Cuomo-Dannenburg, G., McCain, K., McCabe, R., Unwin, H. J. T., Doohan, P., Nash, R. K., Hicks, J. T., Charniga, K., Geismar, C., Lambert, B., et al. (2024) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(23)00515-7 · Cited by 59 · see citing works
“Six CFR estimates were reported, corresponding to the outbreaks in Angola in 2005 [20], DRC in 1999 [12], the original 1968 outbreak in Germany and Yugoslavia [22] and three estimates from the 2012 Uganda outbreak [23] [24] (Figure S2A).”
InfluentialTransmission Potential and Design of Adequate Control Measures for Marburg Hemorrhagic Fever
Ajelli, M., & Merler, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050948 · Cited by 44 · see citing works
- Authors
- Martini, G. A.
- Affiliations
- Philipps University of Marburg (DE)
- Corresponding author
- Martini, G A
- Venue
- Postgraduate Medical Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 1973-08-01
- Volume
- 49
- Issue
- 574
- Pages
- 542-546
- ISSN
- 0032-5473 (ISSN-L)
- 1469-0756
- PMC
- PMC2495590
- OpenAlex
- W2093709831
- Cited by
- 101
- References
- 0
- Citations by year
- 2026: 5 · 2025: 11 · 2024: 8 · 2023: 7 · 2022: 2 · 2021: 4 · 2020: 4 · 2019: 3 · 2018: 4 · 2017: 3 · 2016: 6 · 2015: 5 · 2014: 3 · 2013: 3 · 2012: 5
- FWCI
- 0.95
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Postgraduate Medical Journal (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Vectors
- Health Sciences › Medicine › Infectious Diseases › Viral Infections and Outbreaks Research
- Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
- Keywords
- Marburg virus disease, Marburg virus, filoviruses, zoonotic transmission, vervet monkey, hemorrhagic fever, central nervous system involvement, incubation period, clinical features
- MeSH terms
- Animals, Haplorhini, Blood Cell Count, Brain, Central Nervous System Diseases, Complement Fixation Tests, Diarrhea, Female, Headache, Hemorrhagic Disorders, Humans, Liver, Liver Diseases, Lymph Nodes, Male, Monkey Diseases, Muscular Diseases, RNA Viruses, Skin Diseases, Virus Diseases, Zoonoses
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