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Cited by 66Thyroid Disorders and TreatmentsThyroid and Parathyroid SurgeryThyroid Cancer Diagnosis and Treatment

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

The natural history of euthyroid multinodular goitre

Open access
Elte, J W F, Bussemaker, J K, Haak, A·1990·Postgraduate Medical Journal
DOI 10.1136/pgmj.66.773.186PMC PMC2429462
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Abstract

Summary: In this communication data on the natural history of euthyroid multinodular goitres are presented. From a total group of 140 patients (mean age 54.6 years, 14 men and 126 women; 88 with autonomous, 52 with non-autonomous function), follow-up data were available for 90 patients (mean age 54.0 years, 11 men and 79 women; 64 with autonomous, 26 with non-autonomous function). During follow-up (means: 5.0 years, maximum 12.2 years) transitions in function were seen 15 times; 8 autonomous patients became hyperthyroid after < 1–7 years. There were 6 transitions from non-autonomy to autonomy and 1 from autonomy to non-autonomy. One patient who demonstrated the whole cycle from non-autonomy through autonomy up to hyperthyrodism is described in more detail. In one patient operated upon because of hyperparathyroidism a follicular carcinoma was found by chance. Mechanical problems were the reason for surgery in 6 patients only, 16 patients were operated upon because of cosmetic reasons (mostly in the early years of the study). Finally, results from 19 TRH tests in 16 autonomous patients suggest that TRH tests in patients with autonomously functioning euthyroid multinodular goitres are not yet redundant.

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Crossref · 10.1136/pgmj.66.773.186

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Research works printed but not linked: 4

  1. Sokal, J.E. A long-term follow-up ofnontoxic nodular goiter. Arch Int Med 1957, 99: 60-69.
  2. Bondeson, L. & Ljungberg, O. Occult thyroid carcinoma at autopsy in Malmo, Sweden. Cancer 1981, 47: 319-323.
  3. Frey, W.K. Die Aufgaben der konventionellen Rontgendiagnostik der Schilddriise. Akt Endokr Stoffw 1983, 4: 2-8.
  4. Studer, H., Peter, H.J. & Gerber, H. Toxic nodular goitre. Clin Endocrinol Metab 1985, 14: 351-372.

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Metadata

Authors
Elte, J. W. F., Bussemaker, J. K., & Haak, A.
Affiliations
  • Sint Franciscus Gasthuis (NL)
  • Department of Endocrinology, University Hospital , Leiden, The Netherlands
  • Bronovo Hospital (NL)
Corresponding author
Elte, J W F
Venue
Postgraduate Medical Journal
Publisher
Oxford University Press (OUP)
Published
1990-03-01
Volume
66
Issue
773
Pages
186-190
ISSN
  • 0032-5473 (ISSN-L)
  • 1469-0756
DOI
10.1136/pgmj.66.773.186
PMC
PMC2429462
OpenAlex
W1986910075
Cited by
66
References
30
Citations by year
2024: 2 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 1 · 2015: 6 · 2014: 3 · 2012: 2
FWCI
0.63
Type
journal article
Language
en
Open access
Licence
academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations
  • Postgraduate Medical Journal (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
  • Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
Keywords
natural history (disease), autonomous thyroid function, hyperthyroidism, TRH stimulation test, follicular carcinoma, cosmetic surgery
MeSH terms
Adult, Female, Follow-Up Studies, Goiter, Nodular, Humans, Hyperthyroidism, Male, Middle Aged, Thyroid Neoplasms, Thyrotropin, Thyrotropin-Releasing Hormone, Thyroxine, Triiodothyronine

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CoChat. (2026). Citation check: The natural history of euthyroid multinodular goitre. https://app.cochat.ai/papers/10.1136/pgmj.66.773.186
The paper
Elte, J. W. F., Bussemaker, J. K., & Haak, A. (1990). The natural history of euthyroid multinodular goitre. Postgraduate Medical Journal. https://doi.org/10.1136/pgmj.66.773.186