The DOI matches its Crossref record; 239 of the 248 references it cites were found in a registry or an index.
Systematic literature review informing the EULAR recommendations for the non-pharmacological management of systemic lupus erythematosus and systemic sclerosis
Open accessAbstract
Through this systematic literature review, we assembled evidence to inform the EULAR recommendations for the non-pharmacological management of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc). We screened articles published between January 2000 and June 2021. Studies selected for data extraction (118 for SLE and 92 for SSc) were thematically categorised by the character of their intervention. Of 208 articles included, 51 were classified as robust in critical appraisal. Physical activity was the most studied management strategy and was found to be efficacious in both diseases. Patient education and self-management also constituted widely studied topics. Many studies on SLE found psychological interventions to improve quality of life. Studies on SSc found phototherapy and laser treatment to improve cutaneous disease manifestations. In summary, non-pharmacological management of SLE and SSc encompasses a wide range of interventions, which can be combined and provided either with or without adjunct pharmacological treatment but should not aim to substitute the latter when this is deemed required. While some management strategies i.e., physical exercise and patient education, are already established in current clinical practice in several centres, others e.g., phototherapy and laser treatment, show both feasibility and efficacy, yet require testing in more rigorous trials than those hitherto conducted.
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“Expert consensus, including EULAR recommendations, emphasizes a multidisciplinary approach for systemic lupus erythematosus and systemic sclerosis, highlighting the importance of patient education, psychosocial support, and physical therapy in routine care [97].”
From Chronic Stress and Autoimmunity: The Role of HPA Axis and Cortisol Dysregulation (2025) · cites this paper as [97]
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Items 201–239 of 239
Sheikh, S. Z., Kaufman, K. P., Gordon, B. B., Hicks, S., Love, A. H., Walker, J., Callahan, L. F., & Cleveland, R. J. (2019) · Lupus · doi:10.1177/0961203319846387 · Cited by 14
Cüzdan, N., Türk, İ., Çiftçi, V., Arslan, D., Doğan, M. C., & Ünal, İ. (2021) · Archives of Rheumatology · doi:10.46497/archrheumatol.2021.8295 · Cited by 14
Pettersson, H., Nordin, A., Svenungsson, E., Alexanderson, H., & Boström, C. (2020) · Musculoskeletal Care · doi:10.1002/msc.1447 · Cited by 14
Self-citationSahebari, M., Ebrahimabad, M. J. A., Shoraketokanlo, A. A., Sharbaf, H. A., & Khodashahi, M. (2019) · Iranian Journal of Psychiatry · doi:10.18502/ijps.v14i2.992 · Cited by 13
Ganachari, M., & Almas, S. A. (2012) · Indian Journal of Rheumatology · doi:10.1016/s0973-3698(12)60003-x · Cited by 13
Zhou, J., Yang, D. L., Zhou, S., Wang, J., Liu, Y.-S., & Wang, S. (2017) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-017-2954-2 · Cited by 13
Willems, L. M., Redmond, A. C., Stamm, T., Boström, C., Decuman, S., KENNEDY, A. T., Brozd, J., Roškar, S., Smith, V., Vlieland, T. P. M. V., et al. (2015) · PubMed · Cited by 12
Self-citationCardiovascular Disease Prevention Counseling Program for Systemic Lupus Erythematosus Patients
Yelnik, C., Richey, M., Haiduc, V. F., Everett, S., Zhang, M., & Erkan, D. (2016) · Arthritis Care & Research · doi:10.1002/acr.23128 · Cited by 12
Sahebalzamani, M., Farahani, H., Jamarani, M. T., Faezi, S. T., Moradi, K., & Paragomi, P. (2016) · Rehabilitation Nursing · doi:10.1002/rnj.283 · Cited by 12
Dewi, S., Isbagio, H., Purwaningsih, E. H., Kertia, N., Setiabudy, R., & Setiati, S. (2019) · Acta medica Indonesiana · Cited by 12
Landim, S. F., Bértolo, M. B., del Rio, A. P., Sachetto, Z., Gaino, J. Z., Poole, J. L., & Magalhães, E. D. P. (2020) · Lara D. Veeken · doi:10.1093/rheumatology/keaa140 · Cited by 12
Ritschl, V., Ferreira, R. J. O., Santos, E. J. F., Fernandes, R., Juutila, E., Mosor, E., Santos‐Costa, P., Fligelstone, K., Schraven, L., Stummvoll, G. H., et al. (2021) · RMD Open · doi:10.1136/rmdopen-2021-001710 · Cited by 12
Self-citationZanatta, E., Rodeghiero, F., Pigatto, E., Galozzi, P., Polito, P., Favarò, M., Punzi, L., & Cozzi, F. (2017) · British Journal of Occupational Therapy · doi:10.1177/0308022617698167 · Cited by 11
Rehabilitation of the face and temporomandibular joint in systemic sclerosis
Bongi, S. M., Passalacqua, M., Landi, G., Mikhaylova, S., Tofani, L., Rosso, A. D., Aoufy, K. E., Baccini, M., Matucci‐Cerinic, M., & Melchiorre, D. (2021) · Therapeutic Advances in Musculoskeletal Disease · doi:10.1177/1759720x211020171 · Cited by 11
Defi, I. R., Gultom, C., Chorman, M. J., & Jennie, J. (2021) · Reumatologia/Rheumatology · doi:10.5114/reum.2021.105454 · Cited by 11
do Prado, D., Gualano, B., Miossi, R., Lima, F., Roschel, H., Borba, E. F., Bonfá, E., & Pinto, A. L. D. S. (2011) · Lupus · doi:10.1177/0961203311425525 · Cited by 10
Oliveira, F. A. P., dos Santos, F. D. M. M., Dias, A. F. M. D. P., Neiva, C. L. S., Telles, R. W., & Lanna, C. C. D. (2020) · Lupus · doi:10.1177/0961203320947802 · Cited by 9
Miljeteig, K., & Graue, M. (2009) · Journal of Nursing and Healthcare of Chronic Illness · doi:10.1111/j.1365-2702.2008.01010.x · Cited by 8
Kristensen, L. Q., Oestergaard, L. G., Bovbjerg, K., Rolving, N., & Søndergaard, K. H. (2019) · Hand Therapy · doi:10.1177/1758998318824346 · Cited by 8
Neuromuscular taping enhances hand function in patients with systemic sclerosis: a pilot study.
Parisi, S., Celletti, C., Scarati, M., Priora, M., Laganà, A., Peroni, C. L., Camerota, F., Torre, G. L., Blow, D., & Fusaro, E. (2017) · PubMed · doi:10.7417/t.2017.2036 · Cited by 7
Amniotic membrane dressings: an effective therapy for SSc-related wounds
Frech, T., McNeill, C., Lebiedz‐Odrobina, D., & Lewis, G. M. (2018) · Lara D. Veeken · doi:10.1093/rheumatology/key410 · Cited by 6
FIORI, G., Marzi, T., Bartoli, F., Bruni, C., Ciceroni, C., Palomba, M., Zolferino, M., Corsi, E., Galimberti, M., Pignone, A. M., et al. (2018) · PubMed · Cited by 6
van Leeuwen, N. M., Boonstra, M., Huizinga, T. W. J., Kaptein, A. A., & de Vries‐Bouwstra, J. K. (2020) · Musculoskeletal Care · doi:10.1002/msc.1453 · Cited by 6
Yuen, H. K., Westwater, C., DeGarmo, J., & Bandyopadhyay, D. (2011) · Journal of Experimental and Integrative Medicine · doi:10.5455/jeim.221111.br.009 · Cited by 5
Self-reported Lupus flare: Association with everyday home and personal product exposure
Squance, M. L., Reeves, G. E. M., Attia, J., Bridgman, H. A., & Guest, M. (2015) · Toxicology Reports · doi:10.1016/j.toxrep.2015.05.010 · Cited by 5
Lange, U., Bogensperger, S., Tarner, I. H., & Müller‐Ladner, U. (2019) · Journal of Scleroderma and Related Disorders · doi:10.1177/2397198318819919 · Cited by 5
Nowicka, D. (2019) · Advances in Dermatology and Allergology · doi:10.5114/ada.2019.83651 · Cited by 5
Xu, H., Teng, Q., Zeng, Y., Tian, C., Yang, B., & Yao, X. (2021) · Journal of Nanomaterials · doi:10.1155/2021/9967676 · Cited by 5
Rehabilitation in systemic sclerosis: proposed personalised rehabilitation programme
Brignoli, E., Frassanito, P., Vercesi, E., Ferretti, C., Felicetti, G., Maestri, R., & Barak, M. (2025) · Giornale italiano di medicina del lavoro ed ergonomia · doi:10.4081/gimle.557 · Cited by 5
Wen, C., Fan, Y., Wang, X.-C., Li, X.-Y., & Lu, K. (2007) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-007-0180-z · Cited by 4
Case series of pulsed dye laser treatment of telangiectasia in 23 patients with systemic sclerosis
Burillo‐Martinez, S., Barrios, M., Velasco‐Tamariz, V., Tous‐Romero, F., Gómez, S. L., & Maroñas‐Jiménez, L. (2017) · International Journal of Dermatology · doi:10.1111/ijd.13595 · Cited by 4
Dionello, C. D. F., Lopes-Souza, P., Rosa, P. V., Santana, A., Marchon, R. N. B., Morel, D. S., Moreira-Marconi, E., Frederico, É. H. F. F., de Sá-Caputo, D. D. C., Coelho-Oliveira, A. C., et al. (2020) · Applied Sciences · doi:10.3390/app11010138 · Cited by 3
Barriers And Motivators for Smoking Cessation in Patients With Systemic Lupus Erythematosus (SLE).
Terrell, D. R., Stewart, L. M., Tolma, E. L., McClain, R., Vesely, S. K., & James, J. A. (2015) · PubMed · Cited by 3
Otto, A. D., Mishler, A. E., Shah, N., Krug, M. M., Phillips, A., Wilson, N., & Kao, A. H. (2011) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000403040.26185.b7 · Cited by 3
O’Connor, S., Durand, M., Hudson, M., Baron, M. G., & Gaudreault, N. (2016) · International journal of osteopathic medicine · doi:10.1016/j.ijosm.2016.06.002 · Cited by 2
Extracorporeal shock wave therapy for digital ulcers associated with systemic sclerosis
Saito, S., Ishii, T., Ito, K., & Shimokawa, H. (2016) · Journal of Scleroderma and Related Disorders · doi:10.5301/jsrd.5000208 · Cited by 2
Shock wave therapy for systemic sclerosis
Belloli, L., Cugno, M., D’Agostino, M. C., Ughi, N., Tedeschi, A., Respizzi, S., & Marasini, B. (2011) · Rheumatology International · doi:10.1007/s00296-011-2277-0 · Cited by 1
Individualized Diet and Lifestyle Modifications Reverse Symptoms of Systemic Lupus Erythematosus
Rothman, D. B., Khan, F., & Rudin, V. (2018) · Iproceedings · doi:10.2196/11804 · Cited by 1
Abdelaziz, S. H. (2020) · Indian Journal of Public Health Research & Development · doi:10.37506/ijphrd.v11i5.9447 · Cited by 1
Research works printed but not linked: 1
- Patterson, 2021, Physical inactivity independently predicts incident depression in a multi-racial/ethnic systemic lupus cohort, Arthritis Care Res, 9
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Parodis, I., Girard-Guyonvarc’h, C., Arnaud, L., Distler, O., Domján, A., van den Ende, C. H. M., Fligelstone, K., Kocher, A., Larosa, M., Lau, M., et al. (2023) · Annals of the Rheumatic Diseases · doi:10.1136/ard-2023-224416 · Cited by 140
Self-citationChronic Stress and Autoimmunity: The Role of HPA Axis and Cortisol Dysregulation
Nunez, S. G., Rabelo, S. P., Subotic, N., Caruso, J. W., & Knezevic, N. N. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26209994 · Cited by 138
“Expert consensus, including EULAR recommendations, emphasizes a multidisciplinary approach for systemic lupus erythematosus and systemic sclerosis, highlighting the importance of patient education, psychosocial support, and physical therapy in routine care [97].”
Justiz-Vaillant, A. A., Gopaul, D. A., Soodeen, S., Arozarena-Fundora, R., Arozarena-Barbosa, O., Unakal, C., Thompson, R., Pandit, B., Umakanthan, S., & Akpaka, P. E. (2024) · Molecules · doi:10.3390/molecules29040747 · Cited by 62
Blaess, J., Geneton, S., Goepfert, T., Appenzeller, S., Bordier, G., Davergne, T., Fuentes-Silva, Y., Haglo, H. P., Hambly, K., Kinnett-Hopkins, D., et al. (2024) · RMD Open · doi:10.1136/rmdopen-2024-004171 · Cited by 38
Self-citationTsoi, A., Gómez, A., Boström, C., Pezzella, D., Chow, J. W., Girard-Guyonvarc’h, C., Stamm, T., Arnaud, L., & Parodis, I. (2024) · Rheumatology International · doi:10.1007/s00296-024-05548-x · Cited by 35
Self-citation
Metadata
- Authors
- Parodis, I., Gomez, A., Tsoi, A., Chow, J. W., Pezzella, D., Girard, C., Stamm, T. A., & Boström, C.
- Affiliations
- Karolinska University Hospital (SE)
- Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
- University of Geneva (CH)
- Ludwig Boltzmann Gesellschaft (AT)
- Karolinska Institutet (SE)
- Corresponding author
- Parodis, Ioannis
- Venue
- RMD Open
- Publisher
- BMJ
- Published
- 2023-08
- Volume
- 9
- Issue
- 3
- Pages
- e003297
- ISSN
- 2056-5933 (ISSN-L)
- PMC
- PMC10401222
- OpenAlex
- W4385480990
- Cited by
- 44
- References
- 248
- Citations by year
- 2026: 12 · 2025: 12 · 2024: 17 · 2023: 3
- FWCI
- 2.00
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- RMD Open (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- European Alliance of Associations for Rheumatology
- Topics
- Health Sciences › Medicine › Rheumatology › Systemic Sclerosis and Related Diseases
- Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
- Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
- Keywords
- systemic lupus erythematosus, systemic sclerosis, non-pharmacological treatment, physical activity, patient education, self-management, psychological intervention, quality of life, phototherapy, laser therapy, cutaneous manifestations, EULAR recommendations
- MeSH terms
- Humans, Lupus Erythematosus, Systemic, Quality of Life, Scleroderma, Systemic
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