The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Failure of mebendazole to cure trichomonal vaginitis resistant to metronidazole: case reports.
Open accessAbstract
After a recent report showing the in vitro susceptibility to mebendazole of a strain of Trichomonas vaginalis that was resistant to metronidazole, we present two cases of metronidazole resistant infection, both of which failed to respond to oral mebendazole.
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In the citing paper
“However, in clinical use, mebendazole failed to cure 2 T. vaginalis patients who did not respond to metronidazole treatment [286].”
From Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update (2021) · cites this paper as [286]
Citations
Cites
In vitro susceptibility of Trichomonas vaginalis to 50 antimicrobial agents
Sears, S. D., & O'Hare, J. (1988) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.32.1.144 · Cited by 61
Research works printed but not linked: 13
- Meingassner JG, Heyworth PG. Intestinal and urogenital flagellates. Antibiot Chemother 1981;30:163-202. · DOI
- Thurner J, Meingassner JG. Isolation of Trichomonas vaginalis resistant to metronidazole. Lancet 1978;ii:738. · DOI
- Forsgren A, Forssman L. Metronidazole-resistant Trichomonas vaginalis. British Journal of Venereal Diseases 1979;55:351-3.
- Kulda J, Vojtechovska M, Tachezy J, Demes P, Kunzova E. Metronidazole resistance of Trichomonas vaginalis as a cause of treatment failure in trichomoniasis: case report. British Journal of Venereal Diseases 1982;S8:394-9.
- Muller M, Meingassner JG, Miller WA, Ledger WJ. Three metronidazole resistant strains of Trichomonas vaginalis from the United States. Am J Obstet Gynecol 1980;138:808-12. · DOI
- Goulton J, Squires S. Metronidazole-resistant Trichomonas vaginalis. Lancet 1982;i:42. · DOI
- Meingassner JG, Thurner J. Strain of Trichomonas vaginalis resistant to metronidazole and other 5-nitroimidazoles. Antimicrob Agents Chemother 1979;15:254-7.
- Willmott F, Say J, Downey D, Hookham A. Zinc and recalcitrant trichomoniasis. Lancet 1983;i:1053. · DOI
- Edwards DI, Thompson EJ, Tomusange J. Inactivation of metronidazole by aerobic organisms. J Antimicrob Chemother 1979;5:315-6. · DOI
- Ralph ED, Clarke DA. Inactivation of metronidazole by anaerobic and aerobic bacteria. Antimicrob Agents Chemother 1978;14:377-83. · DOI
- Sprott MS, Kearns AM. Metronidazole-resistant Bacteroides melaninogenicus. J Antimicrob Chemother 1988;22:951-2. · DOI
- Lindmark DG, Muller M. Antitrichomonad action, mutagenicity, and reduction of metronidazole and other nitroimidazoles. Antimicrob Agents Chemother 1976;10:476-82.
- Muinst GJ, Karlagamis G, Birchen J. Plasma concentrations of mebendazole during treatment of echinococcosis. Eur J Clin Pharmacol 1980;17:375-8. · DOI
Cited by
Sorted by citations
Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update
Chai, J.-Y., Jung, B.-K., & Hong, S.-J. (2021) · The Korean Journal of Parasitology · doi:10.3347/kjp.2021.59.3.189 · Cited by 286
Metadata
- Authors
- Pattman, R. S., Sprott, M. S., Kearns, A. M., & Earnshaw, M.
- ORCID
- Kearns, A M
- Venue
- Sexually Transmitted Infections
- Publisher
- BMJ
- Published
- 1989-08-01
- Volume
- 65
- Issue
- 4
- Pages
- 274-275
- ISSN
- 0007-134X (ISSN-L)
- 1368-4973
- PMC
- PMC1194368
- OpenAlex
- W2147057044
- Cited by
- 15
- References
- 1
- Citations by year
- 2025: 1 · 2021: 1 · 2018: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Sexually Transmitted Infections (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Health Sciences › Medicine › Urology › Urinary Tract Infections Management
- Health Sciences › Medicine › Ophthalmology › Ocular Infections and Treatments
- Keywords
- mebendazole, metronidazole resistance, Trichomonas vaginalis, trichomoniasis, treatment failure
- MeSH terms
- Adult, Drug Resistance, Female, Humans, Mebendazole, Metronidazole, Middle Aged, Trichomonas Vaginitis
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Cite CoChat for the checks on this page, and the paper for its own findings.
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- CoChat. (2026). Citation check: Failure of mebendazole to cure trichomonal vaginitis resistant to metronidazole: case reports. https://app.cochat.ai/papers/10.1136/sti.65.4.274
- The paper
- Pattman, R. S., Sprott, M. S., Kearns, A. M., & Earnshaw, M. (1989). Failure of mebendazole to cure trichomonal vaginitis resistant to metronidazole: case reports. Sexually Transmitted Infections. https://doi.org/10.1136/sti.65.4.274