The DOI matches its Crossref record; 75 of the 75 references it cites were found in a registry or an index.
Determinants and outcomes of physical activity in patients with COPD: a systematic review
Open accessAbstract
BACKGROUND: The relationship between physical activity, disease severity, health status and prognosis in patients with COPD has not been systematically assessed. Our aim was to identify and summarise studies assessing associations between physical activity and its determinants and/or outcomes in patients with COPD and to develop a conceptual model for physical activity in COPD. METHODS: We conducted a systematic search of four databases (Medline, Embase, CINAHL and Psychinfo) prior to November 2012. Teams of two reviewers independently selected articles, extracted data and used the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) to assess quality of evidence. RESULTS: 86 studies were included: 59 were focused on determinants, 23 on outcomes and 4 on both. Hyperinflation, exercise capacity, dyspnoea, previous exacerbations, gas exchange, systemic inflammation, quality of life and self-efficacy were consistently related to physical activity, but often based on cross-sectional studies and low-quality evidence. Results from studies of pharmacological and non-pharmacological treatments were inconsistent and the quality of evidence was low to very low. As outcomes, COPD exacerbations and mortality were consistently associated with low levels of physical activity based on moderate quality evidence. Physical activity was associated with other outcomes such as dyspnoea, health-related quality of life, exercise capacity and FEV1 but based on cross-sectional studies and low to very low quality evidence. CONCLUSIONS: Physical activity level in COPD is consistently associated with mortality and exacerbations, but there is poor evidence about determinants of physical activity, including the impact of treatment.
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Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000100 · Cited by 28,164
Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
(2008) · doi:10.1002/9780470712184 · Cited by 25,048
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00136 · Cited by 10,349
(1985) · Europe PMC (PubMed Central) · Cited by 9,143
Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1. The Cochrane Collaboration
Higgins, J., Green, S. R., & Higgins, J. (2008) · Cited by 5,544
Systematic reviews: CRD's guidance for undertaking reviews in health care
Tacconelli, E. (2010) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(10)70065-7 · Cited by 3,245
GRADE guidelines: a new series of articles in the Journal of Clinical Epidemiology
Guyatt, G. H., Oxman, A. D., Schünemann, H. J., Tugwell, P., & Knottnerus, A. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.09.011 · Cited by 3,094
Bestall, J. C., Paul, E. A., Garrod, R., Garnham, R., Jones, P. W., & Wedzicha, J. A. (1999) · Thorax · doi:10.1136/thx.54.7.581 · Cited by 2,927
Characteristics of physical activities in daily life in chronic obstructive pulmonary disease
Pitta, F., Troosters, T., Spruit, M. A., Probst, V. S., Decramer, M., & Gosselink, R. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200407-855oc · Cited by 1,256
Self-citationGarcia-Aymerich, J., Lange, P., Benet, M., Schnohr, P., & Anto, J. M. (2006) · Thorax · doi:10.1136/thx.2006.060145 · Cited by 1,113
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An official European Respiratory Society statement on physical activity in COPD
Watz, H., Pitta, F., Rochester, C. L., Garcia-Aymerich, J., ZuWallack, R., Troosters, T., Vaes, A. W., Puhan, M. A., Jehn, M., Polkey, M. I., et al. (2014) · European Respiratory Journal · doi:10.1183/09031936.00046814 · Cited by 526
Self-citationGoals of COPD treatment: Focus on symptoms and exacerbations
Vogelmeier, C. F., Román-Rodríguez, M., Singh, D., Han, M. K., Rodríguez-Roisin, R., & Ferguson, G. T. (2020) · Respiratory Medicine · doi:10.1016/j.rmed.2020.105938 · Cited by 371
The minimal important difference in physical activity in patients with COPD
Demeyer, H., Burtin, C., Hornikx, M., Camillo, C. A., Van Remoortel, H., Langer, D., Janssens, W., & Troosters, T. (2016) · PLOS ONE · doi:10.1371/journal.pone.0154587 · Cited by 282
Self-citationDemeyer, H., Louvaris, Z., Frei, A., Rabinovich, R. A., de Jong, C., Gimeno-Santos, E., Loeckx, M., Buttery, S. C., Rubio, N., Van der Molen, T., et al. (2017) · Thorax · doi:10.1136/thoraxjnl-2016-209026 · Cited by 256
Self-citationGimeno-Santos, E., Raste, Y., Demeyer, H., Louvaris, Z., de Jong, C., Rabinovich, R. A., Hopkinson, N. S., Polkey, M. I., Vogiatzis, I., Tabberer, M., et al. (2015) · European Respiratory Journal · doi:10.1183/09031936.00183014 · Cited by 151
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Metadata
- Authors
- Gimeno-Santos, E., Frei, A., Steurer-Stey, C., de Batlle, J., Rabinovich, R. A., Raste, Y., Hopkinson, N. S., Polkey, M. I., van Remoortel, H., Troosters, T., Kulich, K., Karlsson, N., Puhan, M. A., Garcia-Aymerich, J., & on behalf of PROactive consortium
- Venue
- Thorax
- Publisher
- BMJ
- Published
- 2014-02-20
- Volume
- 69
- Issue
- 8
- Pages
- 731-739
- ISSN
- 0040-6376 (ISSN-L)
- 1468-3296
- OpenAlex
- W2142148686
- Cited by
- 398
- References
- 75
- FWCI
- 6.51
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Gimeno-Santos, E., Frei, A., Steurer-Stey, C., de Batlle, J., Rabinovich, R. A., Raste, Y., Hopkinson, N. S., Polkey, M. I., van Remoortel, H., Troosters, T., Kulich, K., Karlsson, N., Puhan, M. A., Garcia-Aymerich, J., & on behalf of PROactive consortium. (2014). Determinants and outcomes of physical activity in patients with COPD: a systematic review. Thorax. https://doi.org/10.1136/thoraxjnl-2013-204763
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