The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Grandmother's smoking when pregnant with the mother and asthma in the grandchild: the Norwegian Mother and Child Cohort Study
Open accessAbstract
BACKGROUND: A trans-generational influence of prenatal tobacco smoke exposure on asthma development has been proposed but the evidence remains sparse. METHODS: We examined the grandmother's smoking when pregnant with the mother in relation to asthma outcomes in the grandchild (current asthma at 36 months (N=53 169, cases=3013), current asthma at 7 years (N=25 394, cases=1265) and dispensed asthma medications at 7 years in the Norwegian Prescription Database (N=45 607, cases=1787)) within the Norwegian Mother and Child Cohort Study (MoBa). We calculated adjusted RR (adj. RR) and 95% CIs using log binomial regression. RESULTS: A total of 23.5% of mothers reported that their mother smoked when pregnant with them. The grandmother's smoking when pregnant with the mother was positively associated with asthma at 36 months (adj. RR 1.15 (95% CI 1.06 to 1.24)), asthma at 7 years (adj. RR 1.21 (95% CI 1.07 to 1.37)) and dispensed asthma medications at 7 years (adj. RR 1.15 (95% CI 1.04 to 1.26)). This positive association did not differ significantly by the mother's smoking status when pregnant with the child (p values for multiplicative interaction >0.1). CONCLUSIONS: The grandmother's smoking when pregnant with the mother increased the risk of asthma in the grandchild independent of the mother's smoking status. However, given limited information on the grandmother's socioeconomic status, asthma status and other factors, unmeasured confounding may be present.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“The Norwegian Mother and Child Cohort Study also found a strong association between grandmaternal smoking during pregnancy and childhood asthma.84”
From Impact of Tobacco Smoke and Nicotine Exposure on Lung Development (2016) · cites this paper as [84]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cohort profile: The Norwegian Mother and Child Cohort Study (MoBa)
Magnus, P. M., Irgens, L. M., Haug, K., Nystad, W., Skjærven, R., & Stoltenberg, C. (2006) · International Journal of Epidemiology · doi:10.1093/ije/dyl170 · Cited by 1,027
Self-citationSelf‐selection and bias in a large prospective pregnancy cohort in Norway
Nilsen, R. M., Vollset, S. E., Gjessing, H. K., Skjærven, R., Klungsøyr, K., Schreuder, P., Alsaker, E. R., Haug, K., Daltveit, A. K., & Magnus, P. M. (2009) · Paediatric and Perinatal Epidemiology · doi:10.1111/j.1365-3016.2009.01062.x · Cited by 836
Joubert, B. R., Håberg, S. E., Nilsen, R. M., Wang, X., Vollset, S. E., Murphy, S. K., Huang, Z., Hoyo, C., Midttun, Ø., Cupul-Uicab, L. A., et al. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1205412 · Cited by 716
Self-citationBurke, H., Leonardi-Bee, J., Hashim, A., Pine-Abata, H., Chen, Y., Cook, D. G., Britton, J. R., & McKeever, T. M. (2012) · Pediatrics · doi:10.1542/peds.2011-2196 · Cited by 711
The nutritional basis of the fetal origins of adult disease
Harding, J. E. (2001) · International Journal of Epidemiology · doi:10.1093/ije/30.1.15 · Cited by 561
Maternal and Grandmaternal Smoking Patterns Are Associated With Early Childhood Asthma
Li, Y., Langholz, B. M., Salam, M. T., & Gilliland, F. D. (2005) · CHEST Journal · doi:10.1016/s0012-3692(15)34472-x · Cited by 380
Neuman, Å., Hohmann, C., Orsini, N., Pershagen, G., Eller, E., Kjaer, H. F., Gehring, U., Granell, R., Henderson, J., Heinrich, J., et al. (2012) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201203-0501oc · Cited by 260
Parental Smoking and Lung Function in Children
Moshammer, H., Hoek, G., Luttmann-Gibson, H., Neuberger, M. A., Antova, T., Gehring, U., Hruba, F., Pattenden, S., Rudnai, P., Slachtova, H., et al. (2006) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200510-1552oc · Cited by 251
Effects of maternal smoking on adverse pregnancy outcomes: examination of the criteria of causation.
Walsh, R. A. (1994) · PubMed · Cited by 220
Maternal and Grandmaternal Smoking Patterns Are Associated With Early Childhood Asthma *
Li, Y. (2005) · CHEST Journal · doi:10.1378/chest.127.4.1232 · Cited by 216
Cited by
Sorted by citations
Items 101–110 of 110
Wegmann, M., Fehrenbach, H., & Krauss‐Etschmann, S. (2015) · Pneumologie · doi:10.1055/s-0041-108313
Epigenética en el asma. Lo esencial
Tordera, M. P. (2016)
Smoking control: challenges and
da Silva, C., & de Araújo, A. J. (2016)
Formula one: best is no formula
Bush, A., & Čustović, A. (2017) · European Respiratory Journal · doi:10.1183/13993003.00105-2017
Long-Term Consequences of Childhood Respiratory Disease
Bush, A., & Sly, P. D. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-44887-1.00015-8
McAllister, R. C. (2018) · ThinkIR: The University of Louisville's Institutional Repository (University of Louisville) · doi:10.18297/etd/3049
“This transgenerational inheritance of asthma has also been shown positively associated in humans in a Norwegian cohort (154).”
BackgroundEARLY PROGRAMMING OF ASTHMA AND ALLERGY: IT IS TIME TO SERIOUSLY THINK OF PRIMARY PREVENTION
García‐Marcos, L. (2018) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2018.12.001
Exploration de nouvelles approches de prise en charge des patients asthmatiques
Phillips-Houlbracq, M., Giovannini‐Chami, L., Guilleminault, L., & Devillier, P. (2021) · Revue des Maladies Respiratoires Actualités · doi:10.1016/s1877-1203(21)00072-0
Being responsible for COPD - lung disease as a manifestation of structural violencePreprint
Williams, P. J., Buttery, S. C., Laverty, A. A., & Hopkinson, N. S. (2023) · medRxiv · doi:10.1101/2023.09.06.23295021
“COPD is closely tied to inequality and deprivation(7, 11, 12), and in particular failure to ensure the health and wellbeing of mothers and children(13).”
BackgroundEchoes of smoke: unwinding multigenerational asthma risk through longitudinal cohorts
McEvoy, C. T., & Spindel, E. R. (2026) · ERJ Open Research · doi:10.1183/23120541.01192-2025
“In addition, the nature of exposure is often different for different generations and their findings are not novel as previous studies have demonstrated asthma risk transmitted across generations [10, 20 – 22].”
Metadata
- Authors
- Magnus, M. C., Haberg, S. E., Karlstad, O., Nafstad, P., London, S. J., & Nystad, W.
- Affiliations
- Norwegian Institute of Public Health (NO)
- National Institutes of Health (US)
- Corresponding author
- Magnus, M. C.
- Venue
- Thorax
- Publisher
- BMJ
- Published
- 2015-01-08
- Volume
- 70
- Issue
- 3
- Pages
- 237-243
- ISSN
- 0040-6376 (ISSN-L)
- PMC
- PMC5034931
- OpenAlex
- W2117150043
- Cited by
- 112
- References
- 36
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 4 · 2023: 4 · 2022: 11 · 2021: 15 · 2020: 10 · 2019: 12 · 2018: 16 · 2017: 6 · 2016: 12 · 2015: 12
- FWCI
- 11.30
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Thorax (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (n01es75558-11-0-1)
- National Institute of Neurological Disorders and Stroke (2UO1 NS047537-06A1, U01NS047537, 1 UO1 NS 047537‐01)
- National Institute of Environmental Health Sciences (N01 ES075558, Z01ES049019, Z01ES025045, ZIAES049019)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Keywords
- transgenerational effects, smoking during pregnancy, prenatal tobacco exposure, childhood asthma, asthma treatment, asthma risk, multiplicative interaction, unmeasured confounding
- MeSH terms
- Adult, Asthma, Child, Child, Preschool, Female, Humans, Mothers, Norway, Pregnancy, Prenatal Exposure Delayed Effects, Drug Prescriptions, Risk Factors, Smoking, Confounding Factors, Epidemiologic, Cohort Effect, Databases, Factual
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
