The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
New perspectives on community-acquired pneumonia in 388 406 patients. Results from a nationwide mandatory performance measurement programme in healthcare quality
Open accessAbstract
BACKGROUND: The database of the German programme for quality in healthcare including data of every hospitalised patient with community-acquired pneumonia (CAP) during a 2-year period (n = 388 406 patients in 2005 and 2006) was analysed. METHODS: End points of the analysis were: (1) incidence; (2) outcome; (3) performance of the CRB-65 (C, mental confusion; R, respiratory rate >or=30/min; B, systolic blood pressure <90 mm Hg or diastolic blood pressure or=65 years) score in predicting death; and (4) lack of ventilatory support as a possible indicator of treatment restrictions. The CRB-65 score was calculated, resulting in three risk classes (RCs). RESULTS: The incidence of hospitalised CAP was 2.75 and 2.96 per 1000 inhabitants/year in 2005 and 2006, respectively, higher for males (3.21 vs 2.52), and strongly age related, with an incidence of 7.65 per 1000 inhabitants/year in patients aged >or=60 years over 2 years. Mortality (13.72% and 14.44%) was higher than reported in previous studies. The CRB-65 RCs accurately predicted death in a three-class pattern (mortality 2.40% in CRB-65 RC 1, 13.43% in CRB-65 RC 2 and 34.39% in CRB-65 RC 3). The first days after admission were consistently associated with the highest risk of death throughout all risk classes. Only a minority of patients who died had received mechanical ventilation during hospitalisation (15.74%). CONCLUSIONS: Hospitalised CAP basically is a condition of the elderly associated with a higher mortality than previously reported. It bears a considerable risk of early mortality, even in low risk patients. CRB-65 is a simple and powerful tool for the assessment of CAP severity. Hospitalised CAP is a frequent terminal event in chronic debilitated patients, and a limitation of treatment escalation is frequently applied.
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A Prediction Rule to Identify Low-Risk Patients with Community-Acquired Pneumonia
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Practice Guidelines for the Management of Community-Acquired Pneumonia in Adults
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Epidemiology and Outcomes of Health-care–Associated Pneumonia
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Guidelines for the management of adult lower respiratory tract infections
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Self-citationHouck, P. M., Bratzler, D. W., Nsa, W., Ma, A., & Bartlett, J. G. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.6.637 · Cited by 796
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Prina, E., Ranzani, O. T., & Torres, A. (2015) · The Lancet · doi:10.1016/s0140-6736(15)60733-4 · Cited by 516
Guidelines for the management of adult lower respiratory tract infections - Summary
Woodhead, M., Blasi, F., Ewig, S., Garau, J., Huchon, G., Ieven, M., Ortqvist, A., Schaberg, T., Torres, A., van der Heijden, G., et al. (2011) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2011.03602.x · Cited by 468
Self-citationPneumococcal infection in adults: burden of disease
Drijkoningen, J. J. C., & Rohde, G. G. U. (2014) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12461 · Cited by 384
Wang, S., Ma, P., Zhang, S., Song, S., Wang, Z., Ma, Y., Xu, J., Wu, F., Duan, L., Yin, Z., et al. (2020) · Diabetologia · doi:10.1007/s00125-020-05209-1 · Cited by 325
COVID‐19 is an emergent disease of aging
Santesmasses, D., Castro, J. P., Zenin, A. A., Shindyapina, A. V., Gerashchenko, M. V., Zhang, B., Kerepesi, C., Yim, S. H., Fedichev, P. O., & Gladyshev, V. N. (2020) · Aging Cell · doi:10.1111/acel.13230 · Cited by 172
Metadata
- Authors
- Ewig, S., Birkner, N., Strauss, R., Schaefer, E., Pauletzki, J., Bischoff, H., Schraeder, P., Welte, T., & Hoeffken, G.
- Venue
- Thorax
- Publisher
- BMJ
- Published
- 2009-05-18
- Volume
- 64
- Issue
- 12
- Pages
- 1062-1069
- ISSN
- 0040-6376 (ISSN-L)
- OpenAlex
- W2098338079
- Cited by
- 403
- References
- 28
- FWCI
- 17.07
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Ewig, S., Birkner, N., Strauss, R., Schaefer, E., Pauletzki, J., Bischoff, H., Schraeder, P., Welte, T., & Hoeffken, G. (2009). New perspectives on community-acquired pneumonia in 388 406 patients. Results from a nationwide mandatory performance measurement programme in healthcare quality. Thorax. https://doi.org/10.1136/thx.2008.109785
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