The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Outdoor air pollution and respiratory health in patients with COPD
Open accessAbstract
OBJECTIVES: Time series studies have shown adverse effects of outdoor air pollution on mortality and hospital admissions in patients with chronic obstructive pulmonary disease (COPD) but panel studies have been inconsistent. This study investigates short-term effects of outdoor nitrogen dioxide, ozone, sulfur dioxide, particulate matter (PM(10)) and black smoke on exacerbations, respiratory symptoms and lung function in 94 patients with COPD in east London. METHODS: Patients were recruited from an outpatient clinic and were asked to complete daily diary cards (median follow-up 518 days) recording exacerbations, symptoms and lung function, and the amount of time spent outdoors. Outdoor air pollution exposure (lag 1 day) was obtained from local background monitoring stations. RESULTS: Symptoms but not lung function showed associations with raised pollution levels. Dyspnoea was significantly associated with PM(10) (increase in odds for an IQR change in pollutant: 13% (95% CI 4% to 23%)) and this association remained after adjustment for other the pollutants measured. An IQR increase in nitrogen dioxide was associated with a 6% (0-13%) increase in the odds of a symptomatic fall in peak flow rate. The corresponding effect sizes for PM(10) and black smoke were 12% (2-25%) and 7% (1-13%), respectively. CONCLUSION: It is concluded that outdoor air pollution is associated with important adverse effects on symptoms in patients with COPD living in London.
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Citations
Cites
Mortality by cause for eight regions of the world: Global Burden of Disease Study
Murray, C. J., & Lopez, A. D. (1997) · The Lancet · doi:10.1016/s0140-6736(96)07493-4 · Cited by 4,043 · cited 1×
“INTRODUCTION Chronic obstructive pulmonary disease (COPD) is increasing in incidence worldwide and is currently the sixth leading cause of death.(1) Patients with COPD are prone to acute deterioration in their chronic symptoms.”
Background
Cited by
Vestbo, J., Hurd, S. S., Agustí, A. G., Jones, P. W., Vogelmeier, C., Anzueto, A., Barnes, P. J., Fabbri, L. M., Martinez, F. J., Nishimura, M., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201204-0596pp · Cited by 15,983
Chronic obstructive pulmonary disease
Barnes, P. J., Burney, P. G. J., Silverman, E. K., Celli, B. R., Vestbo, J., Wedzicha, J. A., & Wouters, E. F. M. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.76 · Cited by 734
Self-citationSinharay, R., Gong, J., Barratt, B., Ohman-Strickland, P., Ernst, S., Kelly, F. J., Zhang, J. (., Collins, P., Cullinan, P., & Chung, K. F. (2018) · The Lancet · doi:10.1016/s0140-6736(17)32643-0 · Cited by 409
MacLeod, M., Papi, A., Contoli, M., Beghé, B., Celli, B. R., Wedzicha, J. A., & Fabbri, L. M. (2021) · Respirology · doi:10.1111/resp.14041 · Cited by 359
Self-citationThe Effects of Air Pollution and Temperature on COPD
Hansel, N. N., McCormack, M. C., & Kim, V. (2016) · COPD: Journal of Chronic Obstructive Pulmonary Disease · doi:10.3109/15412555.2015.1089846 · Cited by 283
Metadata
- Authors
- Peacock, J. L., Anderson, H. R., Bremner, S. A., Marston, L., Seemungal, T. A., Strachan, D. P., & Wedzicha, J. A.
- Venue
- Thorax
- Publisher
- BMJ
- Published
- 2011-04-01
- Volume
- 66
- Issue
- 7
- Pages
- 591-596
- ISSN
- 0040-6376 (ISSN-L)
- OpenAlex
- W2153240783
- Cited by
- 217
- References
- 1
- FWCI
- 10.72
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Peacock, J. L., Anderson, H. R., Bremner, S. A., Marston, L., Seemungal, T. A., Strachan, D. P., & Wedzicha, J. A. (2011). Outdoor air pollution and respiratory health in patients with COPD. Thorax. https://doi.org/10.1136/thx.2010.155358
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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