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Cited by 287Chronic Obstructive Pulmonary Disease (COPD) ResearchMental Health Treatment and AccessAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.

Prevalence of depression in patients with chronic obstructive pulmonary disease: a systematic review

Open access
van Ede, L, Yzermans, C J, Brouwer, H J·1999·Thorax
DOI 10.1136/thx.54.8.688PMC PMC1745552
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Abstract

BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) have repeatedly been characterised as a population of chronically ill patients with a higher than normal prevalence of depression. Susceptibility for depression has been noted in patients with certain other chronic conditions. This systematic review was conducted to achieve a more definite answer to the question: do patients with COPD show a higher than normal prevalence of depression? METHODS: Studies in English language journals were retrieved by an electronic search over the period from 1966 to December 1997 and by an extended search of reference lists, and were included or excluded according to a system of diagnostic and methodological criteria. RESULTS: Ten studies were included, of which only four had a case-control design. Three of the case-control studies reported an increased prevalence of depression among patients with COPD which was statistically significant in only one. The fourth controlled study found a significantly increased depression score among COPD patients. Of the remaining six uncontrolled studies three found a high baseline prevalence of depression among their study group. CONCLUSIONS: An association between COPD and depression was found in the four controlled studies. The two methodologically best conducted studies that did not detect a statistically significant higher prevalence lacked power. The two studies that did find a significant association used a questionable depression measure. The prevalence of depression was high compared with general population figures in three of six non-controlled studies. The empirical evidence for a significant risk of depression in patients with COPD remains inconclusive, due to the poor methodological quality of most of the published studies, the lack of studies with an adequate sample size, and variability in instruments and cut off scores used to measure depression.

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Research works printed but not linked: 4

  1. Bottema BJAM. Diagnostiek van CARA in de huisartsprak- tijk. Dissertation, Amsterdam, 1993.
  2. Bowling A. Measuring disease. Buckingham: Open Univer- sity Press, 1995: 72-84, 152-53, 238-39.
  3. Mulrow CD, Oxman AD, eds. Cochrane Collaboration Hand- book. Available in the Cochrane library. The Cochrane Collaboration; Issue 1. Oxford: Update Software, 1997.
  4. Bijl RV, Van Zessen G, Ravelli A. Psychiatric morbidity among adults in the Netherlands: the NEMESIS study. II. Prevalence of psychiatric disorders (in Dutch). Ned Tijdschr Geneeskd 1997;141:2453-60.

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Metadata

Authors
van Ede, L., Yzermans, C. J., & Brouwer, H. J.
Affiliations
Amsterdam UMC Location University of Amsterdam (NL)
Venue
Thorax
Publisher
BMJ
Published
1999-08-01
Volume
54
Issue
8
Pages
688-692
ISSN
0040-6376 (ISSN-L)
DOI
10.1136/thx.54.8.688
PMC
PMC1745552
OpenAlex
W2120845288
Cited by
287
References
42
Citations by year
2026: 2 · 2025: 4 · 2024: 3 · 2023: 3 · 2022: 4 · 2021: 8 · 2020: 7 · 2019: 5 · 2018: 6 · 2017: 13 · 2016: 9 · 2015: 3 · 2014: 26 · 2013: 14 · 2012: 13
FWCI
1.18
Type
journal article
Language
en
Open access
Locations
  • Thorax (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • UvA-DARE (University of Amsterdam) (publishedVersion)
  • Pure Amsterdam UMC (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
chronic obstructive pulmonary disease, depression, depression prevalence, comorbidities, chronic disease, depression measurement, methodological quality
MeSH terms
Aged, Depressive Disorder, Forced Expiratory Volume, Humans, Lung Diseases, Obstructive, Middle Aged, Risk Factors, Vital Capacity, Prevalence, Case-Control Studies

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