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Anatoxin-a, a toxic alkaloid from Anabaena flos-aquae NRC-44h
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A toxic alkaloid, anatoxin-a, has been isolated from mass cultures of a unialgal clone, NRC-44h, of the freshwater blue-green algae Anabaena flos-aquae (Lyngb.) de Bréb., and its structure determined.
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“The latter toxin may pose a health risk because it is an acetylcholine receptor agonist causing paralysis, muscle contractions, and respiratory failure [36].”
From Application of Arthrospira platensis for Medicinal Purposes and the Food Industry: A Review of the Literature (2023) · cites this paper as [36]
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Algae, Man and the Environment
Prescott, G. W., & Jackson, D. F. (1969) · Transactions of the American Microscopical Society · doi:10.2307/3224510 · Cited by 290
Flagged first, then by citations
Research works printed but not linked: 12
- P. R. ORH HAM. In Algae and man. Edited by D. F . Jackson. Plenum Press, New York, NY. 1964. p. 307.
- J. G. GENTILE. In Microbiol toxins. Vol. 7. Edited by S. Kadis, A. Ciegler. and A. J. Ajl. Academic Press, New York. NY. 1971. p. 27.
- M. SHILO. In Microbiol toxins. Vol. 7. Edited by S. Kadis, A. Ciegler, and S. J. Ajl. Academic Press, New York, NY. 1971. p. 67.
- H. KONST, P. D. MCKERCHER, P. R. GORHAM, A. ROBERTSON, and J . HOWELL. Can. J. Comp. Med. Vet. Sci. 29, 221 (1965).
- J. R . 4 ~4 MURTHY and J . B. CAPINDALE. Can. J. Biochem. 48, 508 (1970).
- M. ALAM, M. IKAWA, J. J. SASXER, JR.. and P. 1. SAWYER. Toxicon, 11,65 (1973).
- Y. HASHIMOTO, T. OKAISHI, L. D. DANG, and T. NOGUCHI. Bull. Jpn. Soc. Sci. Fish. 34,528 (1968).
- P. R. GORHAM. J. MCLACHLAN. U. T. HAMMER, and W. K. KIM. Verh. Int. Verein. Limnol. 15,796 (1964).
- W. W. CARMICHAEL and P. R. GORHAM. J. Phycol. 10,238 (1974).
- B. STAVRIC and P. R. GORH4hl. Proceedings, Can. Soc. Plant Physiol. Annual Meeting, University of British Columbia, Abstracts. 1966. p. 20.
- C. S. HUBER. Acta Crystallogr. Ser. B, 78, 2577 (1972).
- P. R. GORHAM. Can. Vet. J. 1, 235 (1960).
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“1 (Devlin et al., 1977).”
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Metadata
- Authors
- Devlin, J. P., Edwards, O. E., Gorham, P. R., Hunter, N. R., Pike, R. K., & Stavric, B.
- ORCID
- Devlin, J. P.
- Venue
- Canadian Journal of Chemistry
- Publisher
- Canadian Science Publishing
- Published
- 1977-04-15
- Volume
- 55
- Issue
- 8
- Pages
- 1367-1371
- ISSN
- 0008-4042 (ISSN-L)
- 1480-3291
- OpenAlex
- W2015312835
- Cited by
- 378
- References
- 1
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 13 · 2023: 13 · 2022: 11 · 2021: 16 · 2020: 18 · 2019: 14 · 2018: 9 · 2017: 11 · 2016: 19 · 2015: 12 · 2014: 17 · 2013: 12 · 2012: 14
- FWCI
- 3.77
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Canadian Journal of Chemistry (publishedVersion)
- Topics
- Physical Sciences › Environmental Science › Environmental Chemistry › Aquatic Ecosystems and Phytoplankton Dynamics
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Microbial Natural Products and Biosynthesis
- Physical Sciences › Environmental Science › Environmental Chemistry › Marine Toxins and Detection Methods
- Keywords
- anatoxin-a, toxic alkaloids, Anabaena flos-aquae, cyanobacteria, structure elucidation, natural product isolation, mass culture
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