The DOI matches its Crossref record; 130 of the 130 references it cites were found in a registry or an index.
Present and Future of Culturing Bacteria
Open accessAbstract
The cultivation of bacteria is highly biased toward a few phylogenetic groups. Many of the currently underexplored bacterial lineages likely have novel biosynthetic pathways and unknown biochemical features. New cultivation concepts have been developed based on an improved understanding of the ecology of previously not-cultured bacteria. Particularly successful were improved media that mimic the natural types and concentrations of substrates and nutrients, high-throughput cultivation techniques, and approaches that exploit biofilm formation and bacterial interactions. Metagenomics and single-cell genomics can reveal unknown metabolic features of not-yet-cultured bacteria and, if complemented by culture-independent physiological analyses, will help to target functional novelty more efficiently. However, numerous novel types of bacteria that were initially enriched subsequently escaped isolation. Future cultivation work will therefore need to focus on improved subcultivation, purification, and preservation techniques to recover and utilize a larger fraction of microbial diversity.
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1 retracted
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RetractedEscherichia coli and Salmonella :cellular and molecular biology
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Structure and function of the global ocean microbiome
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A new view of the tree of life
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Challenges of unculturable bacteria: environmental perspectives
Bodor, A., Bounedjoum, N., Vincze, G. E., Erdeiné Kis, Á., Laczi, K., Bende, G., Szilágyi, Á., Kovács, T., Perei, K., & Rákhely, G. (2020) · Reviews in Environmental Science and Bio/Technology · doi:10.1007/s11157-020-09522-4 · Cited by 348
Unifying the known and unknown microbial coding sequence space
Vanni, C., Schechter, M. S., Acinas, S. G., Barberán, A., Buttigieg, P. L., Casamayor, E. O., Delmont, T. O., Duarte, C. M., Eren, A. M., Finn, R. D., et al. (2022) · eLife · doi:10.7554/elife.67667 · Cited by 134
Microbiome modeling: a beginner's guide
Lange, E., Kranert, L., Krüger, J., Benndorf, D., & Heyer, R. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1368377 · Cited by 21
Metadata
- Authors
- Overmann, J., Abt, B., & Sikorski, J.
- Venue
- Annual Review of Microbiology
- Publisher
- Annual Reviews
- Published
- 2017-09-08
- Volume
- 71
- Issue
- 1
- Pages
- 711-730
- ISSN
- 0066-4227 (ISSN-L)
- 1545-3251
- OpenAlex
- W2598819529
- Cited by
- 282
- References
- 130
- FWCI
- 2.15
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
