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Cited by 541

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Epstein–Barr Virus and Cancer

Farrell, Paul J.·2019·Annual Review of Pathology: Mechanisms of Disease

Abstract

Epstein–Barr virus (EBV) contributes to about 1.5% of all cases of human cancer worldwide, and viral genes are expressed in the malignant cells. EBV also very efficiently causes the proliferation of infected human B lymphocytes. The functions of the viral proteins and small RNAs that may contribute to EBV-associated cancers are becoming increasingly clear, and a broader understanding of the sequence variation of the virus genome has helped to interpret their roles. The improved understanding of the mechanisms of these cancers means that there are great opportunities for the early diagnosis of treatable stages of EBV-associated cancers and the use of immunotherapy to target EBV-infected cells or overcome immune evasion. There is also scope for preventing disease by immunization and for developing therapeutic agents that target the EBV gene products expressed in the cancers.

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Crossref · 10.1146/annurev-pathmechdis-012418-013023

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Metadata

Authors
Farrell, P. J.
Venue
Annual Review of Pathology: Mechanisms of Disease
Published
2019-01-24
Volume
14
Issue
1
Pages
29-53
ISSN
  • 1553-4006 (ISSN-L)
  • 1553-4014
OpenAlex
W2888204442
Cited by
541
References
3
FWCI
5.87
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Epstein–Barr Virus and Cancer. https://app.cochat.ai/papers/10.1146/annurev-pathmechdis-012418-013023
The paper
Farrell, P. J. (2019). Epstein–Barr Virus and Cancer. Annual Review of Pathology: Mechanisms of Disease. https://doi.org/10.1146/annurev-pathmechdis-012418-013023

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.