The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
The Signal Recognition Particle
Abstract
▪ Abstract The signal recognition particle (SRP) and its membrane-associated receptor (SR) catalyze targeting of nascent secretory and membrane proteins to the protein translocation apparatus of the cell. Components of the SRP pathway and salient features of the molecular mechanism of SRP-dependent protein targeting are conserved in all three kingdoms of life. Recent advances in the structure determination of a number of key components in the eukaryotic and prokaryotic SRP pathway provide new insight into the molecular basis of SRP function, and they set the stage for future work toward an integrated picture that takes into account the dynamic and contextual properties of this remarkable cellular machine.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The GTPase superfamily: conserved structure and molecular mechanism
Bourne, H. R., Sanders, D. A., & McCormick, F. (1991) · Nature · doi:10.1038/349117a0 · Cited by 3,392
Ulbrandt, N. D., Newitt, J. A., & Bernstein, H. D. (1997) · Cell · doi:10.1016/s0092-8674(00)81839-5 · Cited by 332
Structure of the conserved GTPase domain of the signal recognition particle.
Freymann, D. M., Keenan, R. J., Stroud, R. M., & Walter, P. (1997) · Nature · doi:10.1038/385361a0 · Cited by 228
Self-citationCrystal structure of the NG domain from the signal-recognition particle receptor FtsY.
Montoya, G., Svensson, C., Luirink, J., & Sinning, I. (1997) · Nature · doi:10.1038/385365a0 · Cited by 210
Protein translocation in the three domains of life: variations on a theme.
Pohlschröder, M., Prinz, W. A., Hartmann, E., & Beckwith, J. (1997) · Cell · doi:10.1016/s0092-8674(00)80443-2 · Cited by 187
Cited by
Stanley, S. A., Raghavan, S., Hwang, W. W., & Cox, J. S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2235593100 · Cited by 570
Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration
Gass, J., Cannon, A., Mackenzie, I. R., Boeve, B., Baker, M., Adamson, J., Crook, R., Melquist, S., Kuntz, K., Petersen, R., et al. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddl241 · Cited by 580
Recombinant protein secretion in Escherichia coli
Mergulhão, F. J. M., Summers, D. K., & Monteiro, G. A. (2005) · Biotechnology Advances · doi:10.1016/j.biotechadv.2004.11.003 · Cited by 485
Biochemistry and Molecular Biology of Flaviviruses
Barrows, N. J., Campos, R. K., Liao, K.-C., Prasanth, K. R., Soto-Acosta, R., Yeh, S.-C., Schott-Lerner, G., Pompon, J., Sessions, O. M., Bradrick, S. S., et al. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00719 · Cited by 341
Substrate twinning activates the signal recognition particle and its receptor
Egea, P. F., Shan, S.-O., Napetschnig, J., Savage, D. F., Walter, P., & Stroud, R. M. (2004) · Nature · doi:10.1038/nature02250 · Cited by 288
Self-citation
Metadata
- Authors
- Keenan, R. J., Freymann, D. M., Stroud, R. M., & Walter, P.
- Venue
- Annual Review of Biochemistry
- Publisher
- Annual Reviews
- Published
- 2001-06
- Volume
- 70
- Issue
- 1
- Pages
- 755-775
- ISSN
- 0066-4154 (ISSN-L)
- 1545-4509
- OpenAlex
- W2137032962
- Cited by
- 633
- References
- 5
- FWCI
- 2.88
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Signal Recognition Particle. https://app.cochat.ai/papers/10.1146/annurev.biochem.70.1.755
- The paper
- Keenan, R. J., Freymann, D. M., Stroud, R. M., & Walter, P. (2001). The Signal Recognition Particle. Annual Review of Biochemistry. https://doi.org/10.1146/annurev.biochem.70.1.755
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
