A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

Wallace, Douglas C.·2005·Annual Review of Genetics

Cites (259)

Items 201–259 of 259

  1. A Stop-Codon Mutation in the Human mtDNA Cytochrome c Oxidase I Gene Disrupts the Functional Structure of Complex IV
    Claudio Bruno, Andrea Martinuzzi, Yingying Tang, Antoni L. Andreu, Francesco Pallotti, Eduardo Bonilla, Sara Shanske, Jin Fu, Carolyn M. Sue, Corrado Italo Angelini et al. · 1999 · The American Journal of Human Genetics
  2. Suppression of β Cell Energy Metabolism and Insulin Release by PGC-1α
    Yoon, J.Cliff, Xu, Gang, Deeney, Jude T, Yang, Shao-Nian, Rhee, James, Puigserver, Pere, Levens, Adah R, Yang, Ruojing, Zhang, Chen-Yu, Lowell, Bradford B et al. · 2003 · Developmental Cell
  3. Familial multisystem degeneration with parkinsonism associated with the 11778 mitochondrial DNA mutation
    Simon, D.K., Pulst, S.M., Sutton, J.P., Browne, S.E., Beal, M.F., Johns, D.R. · 1999 · Neurology
  4. A Gly482Ser Missense Mutation in the Peroxisome Proliferator-Activated Receptor γ Coactivator-1 Is Associated With Altered Lipid Oxidation and Early Insulin Secretion in Pima Indians
    Yunhua L. Muller, Clifton Bogardus, Oluf Borbye Pedersen, Leslie J. Baier · 2003 · Diabetes
  5. Porin interaction with hexokinase and glycerol kinase: Metabolic microcompartmentation at the outer mitochondrial membrane
    Volker Adams, Lisa Griffin, Jeffrey Allen Towbin, Bruce D. Gelb, Kim C. Worley, Edward R.B. McCabe · 1991 · Biochemical Medicine and Metabolic Biology
  6. Prostate Cancer Incidence and Mortality Rates and Trends in the United States and Canada
    Kathleen McDavid, Judy J. Lee, John P Fulton, Jon M. Tonita, Trevor Thompson · 2004 · Public Health Reports
  7. Genetic differences in effects of food restriction on aging in mice
    Harrison, D.E., Archer, J.R. · 1987 · The Journal of Nutrition
  8. Genetic, metabolic and clinical characteristics of maturity onset diabetes of the young
    Gilberto Velho, Philippe Froguel · 1998 · European Journal of Endocrinology
  9. Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells
    Yong Xu, Anuradha Krishnan, X. Steven Wan, Hideyuki J. Majima, Che‐Chung Yeh, Gabriele Ludewig, Edward J. Kasarskis, Daret K. St. Clair · 1999 · Oncogene
  10. Model Organisms as a Guide to Mammalian Aging
    Heidi A. Tissenbaum, Leonard Guarente · 2002 · Developmental Cell
  11. Phylogenetic analysis of the mitochondrial genome indicates significant differences between patients with Alzheimer disease and controls in a French-Canadian founder population.
    P. Chagnon, M. Gee, M. Filion, Y. Robitaille, Majid Belouchi, Denis Gauvreau · 1999 · American journal of medical genetics
  12. Paradoxes in longevity: sequence analysis of mtDNA haplogroup J in centenarians
    Giuseppina Rose, Giuseppe Passarino, Giuseppina Carrieri, Katia Altomare, Valentina Greco, Stefano Bertolini, Massimiliano Bonafè, Claudio Franceschi, Giovanna De Benedictis · 2001 · European Journal of Human Genetics
  13. Detection of hydroxyl radical in the mitochondria of ischemic-reperfused myocardium by trapping with salicylate
    Dipak K. Das, Anna George, Xuekun Liu, Parinum S. Rao · 1989 · Biochemical and Biophysical Research Communications
  14. PGC-1α
    Sander M. Houten, Johan H. Auwerx · 2004 · Cell
  15. p16 is a major inactivation target in hepatocellular carcinoma
    Myung Jin Baek, Zhe Piao, Nam‐Gyun Kim, Chan‐Il Park, Eui‐Cheol Shin, Jeon Han Park, Heejung Jung, Chul Geun Kim, Hoguen Kim · 2000 · Cancer
  16. Multi-Organ Characterization of Mitochondrial Genomic Rearrangements in Ad Libitum and Caloric Restricted Mice Show Striking Somatic Mitochondrial DNA Rearrangements with Age
    Simon Melov, Douglas A. Hinerfeld, Luke Esposito, Douglas C. Wallace · 1997 · Nucleic Acids Research
  17. Extensive somatic mitochondrial mutations in primary prostate cancer using laser capture microdissection.
    Junjian Z. Chen, Neriman Gökden, Graham F Greene, Perkins Mukunyadzi, Fred F. Kadlubar · 2002 · PubMed
  18. Control region mtDNA variants: Longevity, climatic adaptation, and a forensic conundrum
    Pinar E. Coskun, Eduardo Ruiz‐Pesini, Douglas C. Wallace · 2003 · Proceedings of the National Academy of Sciences
  19. The age-related accumulation of a mitochondrial DNA control region mutation in muscle, but not brain, detected by a sensitive PNA-directed PCR clamping based method
    Deborah G. Murdock · 2000 · Nucleic Acids Research
  20. Oxidative damage to mitochondrial DNA in spinal motoneurons of transgenic ALS mice
    Hitoshi Warita, Takeshi Hayashi, Tetsuro Murakami, Yasuhiro Manabe, Koji Abe · 2001 · Molecular Brain Research
  21. Marked increase in mitochondrial DNA deletion levels in the cerebral cortex of Huntington's disease patients
    Terzah M. Horton, Brett H. Graham, Marisol Corral‐Debrinski, John M. Shoffner, Allan E. Kaufman, M. F. Beal, Douglas C. Wallace · 1995 · Neurology
  22. Molecular links between aging and adipose tissue
    Frédéric Picard, Leonard Guarente · 2005 · International Journal of Obesity
  23. Mitochondrial genotype associated with longevity and its inhibitory effect on mutagenesis
    Masashi Tanaka, Jian‐Sheng Gong, Jin Zhang, Yoshiji Yamada, Harm‐Jan W. Borgeld, Kunio Yagi · 2000 · Mechanisms of Ageing and Development
  24. A novel gly290asp mitochondrial cytochromebmutation linked to a complex III deficiency in progressive exercise intolerance
    R. Dumoulin, I Sagnol, Thérèse Ferlin, Dominique Bozon, Georges Stepien, Bénédicte Mousson · 1996 · Molecular and Cellular Probes
  25. Mitochondrial DNA rearrangements in aging human brain and in situ PCR of mtDNA
    Simon Melova, Julie A. Schneider, Pinar E. Coskun, David A. A Bennett, Douglas C. Wallace · 1999 · Neurobiology of Aging
  26. Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single‐strand conformation analysis
    Antonio Alonso, Pablo Martı́n, Cristina Albarrán · 1997 · Electrophoresis
  27. Impact of apoE deficiency on oxidative insults and antioxidant levels in the brain
    Charles Ramassamy, Pascale Krzywkowski, Diana A. Averill‐Bates, Suzanne Lussier‐Cacan, Louise Théroux, Yves Christen, Jean Davignon, Judes Poirier · 2001 · Molecular Brain Research
  28. Nutrient intake and gastric cancer in Mexico
    Lizbeth López Carrillo, Malaquías López‐Cervantes, Mary H. Ward, Jaime Bravo-Alvarado, Armando Ramírez‐Espitia · 1999 · International Journal of Cancer
  29. Targeting of hexokinase 1 to liver and hepatoma mitochondria.
    Bruce D. Gelb, Volker Adams, Stephen N. Jones, L D Griffin, Grant R. MacGregor, Edward R.B. McCabe · 1992 · Proceedings of the National Academy of Sciences
  30. SMAD genes in juvenile polyposis
    Stina Roth, Pertti Sistonen, Reijo Salovaara, Akseli Hemminki, Anu Loukola, Marie Johansson, Egle Avizienyte, Karen Cleary, Patrick M. Lynch, Christopher Ian Amos et al. · 1999 · Genes Chromosomes and Cancer
  31. Redox Regulation of the DNA Repair Function of the Human AP Endonuclease Ape1/ref-1
    Mark R. Kelley, Stephen H. Parsons · 2001 · Antioxidants and Redox Signaling
  32. Novel mtDNA mutations and oxidative phosphorylation dysfunction in Russian LHON families
    Michael D. Brown, Sergei Zhadanov, Jon C. Allen, Seyed Hosseini, Nancy J. Newman, Vasily V. Atamonov, Irina E. Mikhailovskaya, R. I. Sukernik, Douglas C. Wallace · 2001 · Human Genetics
  33. The role of cytochrome c oxidase deficient hippocampal neurones in Alzheimer's disease
    D. Cottrell, G. Borthwick, M. Johnson, P. G. Ince, D. Turnbull · 2002 · Neuropathology and Applied Neurobiology
  34. Decreased Brain Protein Levels of Cytochrome Oxidase Subunits in Alzheimer's Disease and in Hereditary Spinocerebella Ataxia Disorders
    Stephen J. Kish, Frank Mastrogiacomo, Mark Guttman, Yoshiaki Furukawa, Jan‐Willem Taanman, Slobodan Dozic, Massimo Pandolfo, Jacques B. Lamarche, Linda M. DiStefano, Li‐Jan Chang · 1999 · Journal of Neurochemistry
  35. Mitochondrial enzyme expression in the hippocampus in relation to Alzheimer-type pathology
    Nagy, Zs., Esiri, M. M., LeGris, M., Matthews, P. M. · 1999 · Acta Neuropathologica
  36. Mitochondrial abnormalities in cybrid cell models of sporadic Alzheimer's disease worsen with passage in culture
    Patricia A. Trimmer, Paula M. Keeney, M. Kate Borland, Frederic A. Simon, Jatanna Almeida, Russell Howard Swerdlow, Janice K. Parks, William Davis Parker, James P. Bennett · 2003 · Neurobiology of Disease
  37. Molecular and Genetic Basis of Neurological Disease
    Anthony H.V. Schapira · 1998 · Spinal Cord
  38. Molecular genetics of Alzheimerʼs disease: the role of β-amyloid and the presenilins
    Anurag Tandon, Ekaterina A. Rogaeva, MICHAEL J. MULLAN, Peter St George‐Hyslop · 2000 · Current Opinion in Neurology
  39. Bilateral striatal necrosis associated with a novel mutation in the mitochondrial ND6 gene
    Abelardo Solano, Manuel Roig-Quilis, Cristòfol Vives-Bauzá, Jose Hernandez‐Peña, Elena García‐Arumí, Ana Playán, Manuel José López-Pérez, Antoni L. Andreu, Julio Montoya · 2003 · Annals of Neurology
  40. Genetics of lifespan in C. elegans: molecular diversity, physiological complexity, mechanistic simplicity
    Siegfried Hekimi, Jason Burgess, Frédéric Bussière, Yan Meng, Claire Y. Bénard · 2001 · Trends in Genetics
  41. Nonalcoholic fatty liver disease: relationship to insulin sensitivity and oxidative stress. Treatment approaches using vitamin E, magnesium, and betaine.
    Lyn Patrick · 2002 · PubMed
  42. Mitochondrial DNA sequence diversity in bipolar affective disorder.
    F. McMahon, Yu-Sheng Chen, S. Patel, J. Kokoszka, Michael D. Brown, A. Torroni, J. DePaulo, D. Wallace · 2000 · American Journal of Psychiatry
  43. Oxidative processes in the brain and non-neuronal tissues as biomarkers of Alzheimer s disease
    Gary E. Gibson · 2002 · Frontiers in bioscience
  44. Presenilin-1 is located in rat mitochondria
    Maria Ankarcrona, Kjell R. Hultenby · 2002 · Biochemical and Biophysical Research Communications
  45. α-Synuclein expression in HEK293 cells enhances the mitochondrial sensitivity to rotenone
    Michael Orth, Sarah J. Tabrizi, Anthony H.V. Schapira · 2003 · Neuroscience Letters
  46. Maternally inherited diabetes and deafness is a distinct subtype of diabetes and associates with a single point mutation in the mitochondrial tRNA(Leu(UUR)) gene
    J M van den Ouweland, H.H.P.J. Lemkes, R. C. Trembath · 1994 · Diabetes
  47. Morphological, Biochemical, and Genetic Support for an Apolipoprotein E Effect on Microtubular Metabolisma
    Allen D. Roses, Gillian Einstein, John R. Gilbert, Michel Goedert, S‐H. HAN, D. HUANG, Christine Hulette, Eliezer Masliah, Margaret Ann Pericak‐Vance, Ann M. Saunders et al. · 1996 · Annals of the New York Academy of Sciences
  48. Genetics of Parkinsonism: a review.
    Jenny R. Vaughan, Mary Beth Davis, Nicholas William Wood · 2001 · PubMed
  49. Overexpression of manganese superoxide dismutase attenuates neuronal death in human cells expressing mutant (G37R) Cu/Zn‐superoxide dismutase
    Shawn W. Flanagan, Richard D. Anderson, Mark A. Ross, Larry W. Oberley · 2002 · Journal of Neurochemistry
  50. Regulation of Physiological Rates in Caenorhabditis elegans by a tRNA-Modifying Enzyme in the Mitochondria
    Jason. Lemieux, Bernard Lakowski, Ashley Webb, Yan Meng, Antonio. Ubach, Frédéric Bussière, Thomas M. Barnes, Siegfried Hekimi · 2001 · Genetics
  51. Genetics of Parkinsonism: a review
    J. R. VAUGHAN, M.B. Davis, N. W. WOOD · 2001 · Annals of Human Genetics
  52. Molecular regulation of angiogenesis and tumorigenesis by signal transduction pathways: evidence of predictable and reproducible patterns of synergy in diverse neoplasms
    Jack L. Arbiser · 2004 · Seminars in Cancer Biology
  53. Oxidative processes in the brain and non-neuronal tissues as biomarkers of Alzheimer's disease
    E. Gibson Gary · 2002 · Frontiers in bioscience
  54. A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants
    T. Jonassen · 2001 · Proceedings of the National Academy of Sciences
  55. Decreased Hippocampal Metabolic Activity in Alzheimer Patients Is Not Reflected in the Immunoreactivity of Cytochrome Oxidase Subunits
    Ronald W. H. Verwer, Karen A. Jansen, Arja A. Sluiter, C.W. Pool, Wouter Kamphorst, Dick Frans Swaab · 2000 · Experimental Neurology
  56. Hexose metabolism in pancreatic islets: Regulation of mitochondrial hexokinase binding
    Francine MALAISSE-LAGAE, Willy Jean Malaisse · 1988 · Biochemical Medicine and Metabolic Biology
  57. Amyloid-β: phylogenesis of a chameleon
    Anatol Kontush, Craig Atwood · 2004 · Brain Research Reviews
  58. Hypoxemia Is Associated With Mitochondrial DNA Damage and Gene Induction: Implications for Cardiac Disease
    Corral-Debrinski, Marisol · 1991 · JAMA
  59. Increased activity of surviving locus ceruleus neurons in Alzheimer's disease
    Moser · 1999 · Pure Amsterdam UMC