The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Antigen Recognition by Class I-Restricted T Lymphocytes
Abstract
The work discussed here offers a unified view of T-cell recognition and suggests that class-I and class-II molecules have a closely related function in the presentation of peptides to T lymphocytes. The epitopes recognized by class I-restricted T cells that have been defined with peptides in the 4-6 hr lysis assay have all been derived from endogenously synthesized proteins expressed by virus infected or transfected cells. Evidence is accumulating that a cytoplasmic degradation system may be involved in the generation of these epitopes. The analysis of the specificity of CTL responses with synthetic peptides has demonstrated the control of immune responses to isolated epitopes by class-I genes and the great diversity of the receptor repertoire for individual class-I-restricted epitopes.
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Cites
Bjorkman, P. J., Saper, M. A., Samraoui, B., Bennett, W. S., Strominger, J. L., & Wiley, D. C. (1987) · Nature · doi:10.1038/329512a0 · Cited by 2,377
Cited by
In search of the ‘missing self’: MHC molecules and NK cell recognition
Ljunggren, H.-G., & Kärre, K. (1990) · Immunology Today · doi:10.1016/0167-5699(90)90097-s · Cited by 2,687
The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP
Ahn, K., Gruhler, A., Galocha, B., Jones, T. R., Wiertz, E. J. H. J., Ploegh, H. L., Peterson, P. A., Yang, Y., & Früh, K. (1997) · Immunity · doi:10.1016/s1074-7613(00)80349-0 · Cited by 477
Jeffery, K. J. M., Usuku, K., Hall, S. E., Matsumoto, W., Taylor, G. P., Procter, J., Bunce, M., Ogg, G. S., Welsh, K. I., Weber, J. N., et al. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.3848 · Cited by 419
Murine B7-H3 is a negative regulator of T cells
Prasad, D. V. R., Nguyen, T., Li, Z., Yang, Y., Duong, J., Wang, Y., & Dong, C. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.4.2500 · Cited by 368
Gaczynska, M., Rock, K. L., Spies, T., & Goldberg, A. L. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.20.9213 · Cited by 312
Metadata
- Authors
- Townsend, A., & Bodmer, H.
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 1989-04
- Volume
- 7
- Issue
- 1
- Pages
- 601-624
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- OpenAlex
- W1990806106
- Cited by
- 1,198
- References
- 1
- FWCI
- 30.50
- Type
- journal article
- Language
- en
- Open access
- closed
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- Townsend, A., & Bodmer, H. (1989). Antigen Recognition by Class I-Restricted T Lymphocytes. Annual Review of Immunology. https://doi.org/10.1146/annurev.iy.07.040189.003125
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
