The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Chemokines and Chemokine Receptors: Biology and Clinical Relevance in Inflammation and AIDS
Abstract
Chemokines constitute a large family of chemotactic cytokines that act at G protein-coupled receptors to regulate diverse biological processes, including leukocyte trafficking, angiogenesis, hematopoiesis, and organogenesis. They are believed to be both beneficial in host defense against infectious agents and harmful in diseases marked by pathologic inflammation; however, actual clinical roles in these areas have not yet been established. Recently, unexpected ways have been discovered in which medically important pathogens, including HIV-1, exploit or subvert the chemokine system. These and other recent results suggest that targeting specific chemokines and chemokine receptors may have therapeutic utility in both inflammation and infectious disease.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease
Berger, E. A., Murphy, P. M., & Farber, J. M. (1999) · Annual Review of Immunology · doi:10.1146/annurev.immunol.17.1.657 · Cited by 2,180
Self-citationInterleukin-8 as a macrophage-derived mediator of angiogenesis
Koch, A. E., Polverini, P. J., Kunkel, S. L., Harlow, L. A., DiPietro, L. A., Elner, V. M., Elner, S. G., & Strieter, R. M. (1992) · Science · doi:10.1126/science.1281554 · Cited by 2,135
A new class of membrane-bound chemokine with a CX3C motif
Bazan, J. F., Bacon, K. B., Hardiman, G., Wang, W., Soo, K., Rossi, D., Greaves, D. R., Zlotnik, A., & Schall, T. J. (1997) · Nature · doi:10.1038/385640a0 · Cited by 2,013
Boring, L., Gosling, J., Cleary, M., & Charo, I. F. (1998) · Nature · doi:10.1038/29788 · Cited by 1,965
Essential involvement of interleukin-8 (IL-8) in acute inflammation
Harada, A., Sekido, N., Akahoshi, T., Wada, T., Mukaida, N., & Matsushima, K. (1994) · Journal of Leukocyte Biology · doi:10.1002/jlb.56.5.559 · Cited by 1,041
Tournamille, C., Colin, Y., Cartron, J. P., & Le Van Kim, C. (1995) · Nature Genetics · doi:10.1038/ng0695-224 · Cited by 741
Karpus, W. J., Lukacs, N. W., McRae, B. L., Strieter, R. M., Kunkel, S. L., & Miller, S. D. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.155.10.5003 · Cited by 482
Gerard, C., Frossard, J. L., Bhatia, M., Saluja, A., Gerard, N. P., Lu, B., & Steer, M. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119734 · Cited by 212
Cited by
Microglia as a source and target of cytokines
Hanisch, U. (2002) · Glia · doi:10.1002/glia.10161 · Cited by 1,645
Molecular pharmacology of inflammation: Medicinal plants as anti-inflammatory agents
Tasneem, S., Liu, B., Li, B., Choudhary, M. I., & Wang, W. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2018.11.001 · Cited by 358
Metzemaekers, M., Vanheule, V., Janssens, R., Struyf, S., & Proost, P. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01970 · Cited by 328
Platelet chemokines and chemokine receptors, linking hemostasis, inflammation, and host defense
GEAR, A. R. L., & CAMERINI, D. (2003) · Microcirculation · doi:10.1038/sj.mn.7800198 · Cited by 317
Altenburg, J. D., & Siddiqui, R. A. (2009) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-08-0385 · Cited by 67
Metadata
- Authors
- Locati, M., & Murphy, M.
- Venue
- Annual Review of Medicine
- Publisher
- Annual Reviews
- Published
- 1999-02
- Volume
- 50
- Issue
- 1
- Pages
- 425-440
- ISSN
- 0066-4219 (ISSN-L)
- 1545-326X
- OpenAlex
- W2137813262
- Cited by
- 283
- References
- 8
- FWCI
- 2.66
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Chemokines and Chemokine Receptors: Biology and Clinical Relevance in Inflammation and AIDS. https://app.cochat.ai/papers/10.1146/annurev.med.50.1.425
- The paper
- Locati, M., & Murphy, M. (1999). Chemokines and Chemokine Receptors: Biology and Clinical Relevance in Inflammation and AIDS. Annual Review of Medicine. https://doi.org/10.1146/annurev.med.50.1.425
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.