The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.
Food Allergy: Recent Advances in Pathophysiology and Treatment
Abstract
Food allergies, defined as an adverse immune response to food proteins, affect as many as 6% of young children and 3%–4% of adults in westernized countries, and their prevalence appears to be rising. In addition to well-recognized acute allergic reactions and anaphylaxis triggered by IgE antibody–mediated immune responses to food proteins, there is an increasing recognition of cell-mediated disorders such as eosinophilic gastroenteropathies and food protein–induced enterocolitis syndrome. We are gaining an increasing understanding of the pathophysiology of food allergic disorders and are beginning to comprehend how these result from a failure to establish or maintain normal oral tolerance. Many food allergens have been characterized at a molecular level, and this knowledge, combined with an increasing appreciation of the nature of humoral and cellular immune responses resulting in allergy or tolerance, is leading to novel therapeutic approaches. Currently, management of food allergies consists of educating the patient to avoid ingesting the responsible allergen and initiating therapy if ingestion occurs. However, numerous strategies for definitive treatment are being studied, including sublingual/oral immunotherapy, injection of anti-IgE antibodies, cytokine/anticytokine therapies, Chinese herbal therapies, and novel immunotherapies utilizing engineered proteins and strategic immunomodulators.
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Furuta, G. T., Liacouras, C. A., Collins, M. H., Gupta, S. K., Justinich, C., Putnam, P. E., Bonis, P., Hassall, E., Straumann, A., & Rothenberg, M. E. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.08.017 · Cited by 1,673
Anatomical basis of tolerance and immunity to intestinal antigens
Mowat, A. M. (2003) · Nature Reviews Immunology · doi:10.1038/nri1057 · Cited by 1,415
Utility of food-specific IgE concentrations in predicting symptomatic food allergy
Sampson, H. A. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.114708 · Cited by 1,362
Self-citationThe prevalence of food allergy: A meta-analysis
Rona, R. J., Keil, T., Summers, C., Gislason, D., Zuidmeer, L., Sodergren, E., Sigurdardottir, S. T., Lindner, T., Goldhahn, K., Dahlstrom, J., et al. (2007) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2007.05.026 · Cited by 1,351
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Further fatalities caused by anaphylactic reactions to food, 2001-2006
Bock, S. A., Muñoz-Furlong, A., & Sampson, H. A. (2007) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2006.12.622 · Cited by 987
Self-citationFactors Associated with the Development of Peanut Allergy in Childhood
Lack, G., Fox, D., Northstone, K., & Golding, J. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa013536 · Cited by 911
Eosinophilic Esophagitis: A 10-Year Experience in 381 Children
Liacouras, C. A., Spergel, J. M., Ruchelli, E., Verma, R., Mascarenhas, M., Semeao, E., Flick, J., Kelly, J., Brown–Whitehorn, T., Mamula, P., et al. (2005) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(05)00885-2 · Cited by 872
Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis
Blanchard, C. (2006) · Journal of Clinical Investigation · doi:10.1172/jci26679 · Cited by 870
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Epithelial crosstalk at the microbiota–mucosal interface
Wells, J. M., Rossi, O., Meijerink, M., & van Baarlen, P. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000092107 · Cited by 579
Katz, Y., Goldberg, M. R., Rajuan, N., Cohen, A., & Leshno, M. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.12.1105 · Cited by 386
Metadata
- Authors
- Sicherer, S. H., & Sampson, H. A.
- Venue
- Annual Review of Medicine
- Publisher
- Annual Reviews
- Published
- 2009-02-01
- Volume
- 60
- Issue
- 1
- Pages
- 261-277
- ISSN
- 0066-4219 (ISSN-L)
- 1545-326X
- OpenAlex
- W2132488375
- Cited by
- 257
- References
- 80
- FWCI
- 2.46
- Type
- journal article
- Language
- en
- Open access
- closed
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- Sicherer, S. H., & Sampson, H. A. (2009). Food Allergy: Recent Advances in Pathophysiology and Treatment. Annual Review of Medicine. https://doi.org/10.1146/annurev.med.60.042407.205711
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
