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Cited by 571

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

AGAINST ALL ODDS: The Survival Strategies of Deinococcus radiodurans

Battista, J. R.·1997·Annual Review of Microbiology

Abstract

▪ Abstract Bacteria of the genus Deinococcus exhibit an extraordinary ability to withstand the lethal and mutagenic effects of DNA damaging agents—particularly the effects of ionizing radiation. These bacteria are the most DNA damage–tolerant organisms ever identified. Relatively little is known about the biochemical basis for this phenomenon; however, available evidence indicates that efficient repair of DNA damage is, in large part, responsible for the deinococci's radioresistance. Obviously, an explanation of the deinococci's DNA damage tolerance cannot be developed solely on the basis of the DNA repair strategies of more radiosensitive organisms. The deinococci's capacity to survive DNA damage suggests that (a) they employ repair mechanisms that are fundamentally different from other prokaryotes, or that (b) they have the ability to potentiate the effectiveness of the conventional complement of DNA repair proteins. An argument is made for the latter alternative.

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Crossref · 10.1146/annurev.micro.51.1.203

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Metadata

Authors
Battista, J. R.
Venue
Annual Review of Microbiology
Published
1997-10
Volume
51
Issue
1
Pages
203-224
ISSN
  • 0066-4227 (ISSN-L)
  • 1545-3251
OpenAlex
W2139751207
Cited by
571
References
1
FWCI
0.76
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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