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Cited by 599

The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.

Functional Modulation of Escherichia Coli RNA Polymerase

Ishihama, Akira·2000·Annual Review of Microbiology

Abstract

▪ Abstract The promoter recognition specificity of Escherichia coli RNA polymerase is modulated by replacement of the σ subunit in the first step and by interaction with transcription factors in the second step. The overall differentiated state of ∼2000 molecules of the RNA polymerase in a single cell can be estimated after measurement of both the intracellular concentrations and the RNA polymerase-binding affinities for all seven species of the σ subunit and 100–150 transcription factors. The anticipated impact from this line of systematic approach is that the prediction of the expression hierarchy of ∼4000 genes on the E. coli genome can be estimated.

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Crossref · 10.1146/annurev.micro.54.1.499

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Metadata

Authors
Ishihama, A.
Venue
Annual Review of Microbiology
Published
2000-10
Volume
54
Issue
1
Pages
499-518
ISSN
  • 0066-4227 (ISSN-L)
  • 1545-3251
OpenAlex
W2171662523
Cited by
599
References
94
FWCI
1.68
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Functional Modulation of Escherichia Coli RNA Polymerase. https://app.cochat.ai/papers/10.1146/annurev.micro.54.1.499
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Ishihama, A. (2000). Functional Modulation of Escherichia Coli RNA Polymerase. Annual Review of Microbiology. https://doi.org/10.1146/annurev.micro.54.1.499

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.