The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Manganese Transport and the Role of Manganese in Virulence
Abstract
Two areas of research have recently converged to highlight important roles for Mn 2+ in pathogenesis: the recognition that both bacterial Nramp homologs and members of LraI family of proteins are Mn 2+ transporters. Their mutation is associated with decreased virulence of various bacterial species. Thus, Mn 2+ appears to be essential for bacterial virulence. This review describes what is currently known about Mn 2+ transport in prokaryotes and how prokaryotic Mn 2+ transport is regulated. Some of the phenotypes that arise when microorganisms lack Mn 2+ are then discussed, with an emphasis on those phenotypes involving pathogenesis. The concluding section describes possible enzymatic roles for Mn 2+ that might help explain why Mn 2+ is necessary for virulence.
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Cites
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
Gunshin, H., Mackenzie, B., Berger, U. V., Gunshin, Y., Romero, M. F., Boron, W. F., Nussberger, S., Gollan, J. L., & Hediger, M. A. (1997) · Nature · doi:10.1038/41343 · Cited by 3,166
Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene
Fleming, M. D., Trenor, C. C., Su, M. A., Foernzler, D., Beier, D. R., Dietrich, W. F., & Andrews, N. C. (1997) · Nature Genetics · doi:10.1038/ng0897-383 · Cited by 1,159
Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg
Vidal, S. M., Malo, D., Vogan, K., Skamene, E., & Gros, P. (1993) · Cell · doi:10.1016/0092-8674(93)90135-d · Cited by 1,104
Richter-Dahlfors, A., Buchan, A. M. J., & Finlay, B. B. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.186.4.569 · Cited by 502
The ZnuABC high‐affinity zinc uptake system and its regulator Zur in Escherichia coli
Patzer, S. I., & Hantke, K. (1998) · Molecular Microbiology · doi:10.1046/j.1365-2958.1998.00883.x · Cited by 490
Dintilhac, A., Alloing, G., Granadel, C., & Claverys, J. (1997) · Molecular Microbiology · doi:10.1046/j.1365-2958.1997.5111879.x · Cited by 380
Kehres, D. G., Zaharik, M. L., Finlay, B. B., & Maguire, M. E. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01922.x · Cited by 292
Self-citationForbes, J. R., & Gros, P. (2003) · Blood · doi:10.1182/blood-2003-02-0425 · Cited by 288
Que, Q., & Helmann, J. D. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01811.x · Cited by 282
Braunstein, M., Espinosa, B. J., Chan, J., Belisle, J. T., & R. Jacobs, W. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03438.x · Cited by 272
Cited by
Nutritional immunity beyond iron: a role for manganese and zinc
Kehl-Fie, T. E., & Skaar, E. P. (2010) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2009.11.008 · Cited by 634
Kehl-Fie, T. E., Chitayat, S., Hood, M. I., Damo, S., Restrepo, N., Garcia, C., Munro, K. A., Chazin, W. J., & Skaar, E. P. (2011) · Cell Host & Microbe · doi:10.1016/j.chom.2011.07.004 · Cited by 419
Damo, S. M., Kehl-Fie, T. E., Sugitani, N., Holt, M. E., Rathi, S., Murphy, W. J., Zhang, Y., Betz, C., Hench, L., Fritz, G., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1220341110 · Cited by 388
Human calprotectin is an iron-sequestering host-defense protein
Nakashige, T. G., Zhang, B., Krebs, C., & Nolan, E. M. (2015) · Nature Chemical Biology · doi:10.1038/nchembio.1891 · Cited by 291
Staphylococcal response to oxidative stress
Gaupp, R., Ledala, N., & Somerville, G. A. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00033 · Cited by 253
Metadata
- Authors
- Papp-Wallace, K. M., & Maguire, M. E.
- Venue
- Annual Review of Microbiology
- Publisher
- Annual Reviews
- Published
- 2006-10-01
- Volume
- 60
- Issue
- 1
- Pages
- 187-209
- ISSN
- 0066-4227 (ISSN-L)
- 1545-3251
- OpenAlex
- W2153803424
- Cited by
- 273
- References
- 18
- FWCI
- 0.73
- Type
- journal article
- Language
- en
- Open access
- closed
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- Papp-Wallace, K. M., & Maguire, M. E. (2006). Manganese Transport and the Role of Manganese in Virulence. Annual Review of Microbiology. https://doi.org/10.1146/annurev.micro.60.080805.142149
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
