The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
DECIPHERING THE GENETIC BASIS OF SPEECH AND LANGUAGE DISORDERS
Open accessAbstract
▪ Abstract A significant number of individuals have unexplained difficulties with acquiring normal speech and language, despite adequate intelligence and environmental stimulation. Although developmental disorders of speech and language are heritable, the genetic basis is likely to involve several, possibly many, different risk factors. Investigations of a unique three-generation family showing monogenic inheritance of speech and language deficits led to the isolation of the first such gene on chromosome 7, which encodes a transcription factor known as FOXP2. Disruption of this gene causes a rare severe speech and language disorder but does not appear to be involved in more common forms of language impairment. Recent genome-wide scans have identified at least four chromosomal regions that may harbor genes influencing the latter, on chromosomes 2, 13, 16, and 19. The molecular genetic approach has potential for dissecting neurological pathways underlying speech and language disorders, but such investigations are only just beginning.
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Cites
Is Specific Language Impairment a valid diagnostic category? Genetic and psycholinguistic evidence
Bishop, D. V. M. (1994) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.1994.0134 · Cited by 116
Examination of the stability of two methods of defining Specific Language Impairment
Cole, K. N., Schwartz, I. S., Notari, A. R., Dale, P. S., & Mills, P. E. (1995) · Applied Psycholinguistics · doi:10.1017/s0142716400006445 · Cited by 25
Cited by
A functional genetic link between distinct developmental language disorders
Vernes, S. C., Newbury, D. F., Abrahams, B. S., Winchester, L., Nicod, J., Groszer, M., Alarcón, M., Oliver, P. L., Davies, K. E., Geschwind, D. H., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0802828 · Cited by 676
Self-citationIdentification of FOXP2 Truncation as a Novel Cause of Developmental Speech and Language Deficits
MacDermot, K. D., Bonora, E., Sykes, N., Coupe, A.-M., Lai, C. S. L., Vernes, S. C., Vargha-Khadem, F., McKenzie, F., Smith, R. L., Monaco, A. P., et al. (2005) · The American Journal of Human Genetics · doi:10.1086/430841 · Cited by 411
Self-citationFoxP2 Expression in Avian Vocal Learners and Non-Learners
Haesler, S., Wada, K., Nshdejan, A., Morrisey, E. E., Lints, T., Jarvis, E. D., & Scharff, C. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.4369-03.2004 · Cited by 398
Neurobiology of dyslexia: a reinterpretation of the data
Ramus, F. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.10.004 · Cited by 384
The eloquent ape: genes, brains and the evolution of language
Fisher, S. E., & Marcus, G. F. (2006) · Nature Reviews Genetics · doi:10.1038/nrg1747 · Cited by 349
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Metadata
- Authors
- Fisher, S. E., Lai, C. S. L., & Monaco, A. P.
- Venue
- Annual Review of Neuroscience
- Publisher
- Annual Reviews
- Published
- 2003-03
- Volume
- 26
- Issue
- 1
- Pages
- 57-80
- ISSN
- 0147-006X (ISSN-L)
- 1545-4126
- OpenAlex
- W2149073468
- Cited by
- 171
- References
- 2
- FWCI
- 2.96
- Type
- journal article
- Language
- en
- Open access
- green
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- Fisher, S. E., Lai, C. S. L., & Monaco, A. P. (2003). DECIPHERING THE GENETIC BASIS OF SPEECH AND LANGUAGE DISORDERS. Annual Review of Neuroscience. https://doi.org/10.1146/annurev.neuro.26.041002.131144
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