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Cited by 216

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

REGULATION OF MILK PROTEIN GENE EXPRESSION

Rosen, Jeffrey M., Wyszomierski, Shannon L., Hadsell, Darryl·1999·Annual Review of Nutrition

Abstract

▪ Abstract Studies using both transgenic mice and transfected mammary epithelial cells have established that composite response elements containing multiple binding sites for several transcription factors mediate the hormonal and developmental regulation of milk protein gene expression. Activation of signal transduction pathways by lactogenic hormones and cell-substratum interactions activate transcription factors and change chromatin structure and milk protein gene expression. The casein promoters have binding sites for signal transducers and activators of transcription 5, Yin Yang 1, CCAAT/enhancer binding protein, and the glucocorticoid receptor. The whey protein gene promoters have binding sites for nuclear factor I, as well as the glucocorticoid receptor and the signal transducers and activators of transcription 5. The functional importance of some of these factors in mammary gland development and milk protein gene expression has been elucidated by studying mice in which some of these factors have been deleted.

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Crossref · 10.1146/annurev.nutr.19.1.407

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Metadata

Authors
Rosen, J. M., Wyszomierski, S. L., & Hadsell, D.
Venue
Annual Review of Nutrition
Published
1999-07
Volume
19
Issue
1
Pages
407-436
ISSN
  • 0199-9885 (ISSN-L)
  • 1545-4312
OpenAlex
W2168220276
Cited by
216
References
4
FWCI
1.26
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: REGULATION OF MILK PROTEIN GENE EXPRESSION. https://app.cochat.ai/papers/10.1146/annurev.nutr.19.1.407
The paper
Rosen, J. M., Wyszomierski, S. L., & Hadsell, D. (1999). REGULATION OF MILK PROTEIN GENE EXPRESSION. Annual Review of Nutrition. https://doi.org/10.1146/annurev.nutr.19.1.407

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.