The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
CYTOCHROME P450: Nature's Most Versatile Biological Catalyst
Abstract
▪ Abstract The author describes studies that led to the resolution and reconstitution of the cytochrome P450 enzyme system in microsomal membranes. The review indicates how purification and characterization of the cytochromes led to rigorous evidence for multiple isoforms of the oxygenases with distinct chemical and physical properties and different but somewhat overlapping substrate specificities. Present knowledge of the individual steps in the P450 and reductase reaction cycles is summarized, including evidence for the generation of multiple functional oxidants that may contribute to the exceptional diversity of the reactions catalyzed.
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Citations
Cites
Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity
Guengerich, F. P. (2001) · Chemical Research in Toxicology · doi:10.1021/tx0002583 · Cited by 1,655
Oxygen Activation by Cytochrome P-4501
White, R. E., & Coon, M. J. (1980) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.49.070180.001531 · Cited by 1,023
Self-citationDing, X., & Kaminsky, L. S. (2003) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.43.100901.140251 · Cited by 822
The P450 Gene Superfamily: Recommended Nomenclature
NEBERT, D. W., ADESNIK, M., COON, M. J., ESTABROOK, R. W., GONZALEZ, F. J., GUENGERICH, F. P., GUNSALUS, I. C., JOHNSON, E. F., KEMPER, B., LEVIN, W., et al. (1987) · DNA · doi:10.1089/dna.1987.6.1 · Cited by 818
Self-citationWang, M., Roberts, D. L., Paschke, R., Shea, T. M., Masters, B. S. S., & Kim, J.-J. P. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.16.8411 · Cited by 744
Mammalian Microsomal Cytochrome P450 Monooxygenase
Williams, P. A., Cosme, J., Sridhar, V., Johnson, E. F., & McRee, D. E. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80408-6 · Cited by 696
A New Cytochrome in Liver Microsomes
Omura, T., & Sato, R. (1962) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)60338-2 · Cited by 684
Pigments of rat liver microsomes
Klingenberg, M. (1958) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(58)90436-3 · Cited by 664
Lu, A. Y. H., & Coon, M. J. (1968) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)56992-7 · Cited by 627
Self-citationCytochrome P450 and the Individuality of Species
Nelson, D. R. (1999) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1999.1352 · Cited by 591
Cited by
Regulation of Reactive Oxygen Species Generation in Cell Signaling
Bae, Y. S., Oh, H., Rhee, S. G., & Yoo, Y. D. (2011) · Molecules and Cells · doi:10.1007/s10059-011-0276-3 · Cited by 658
Yang, Y., & Arnold, F. H. (2021) · Accounts of Chemical Research · doi:10.1021/acs.accounts.0c00591 · Cited by 357
Hanukoglu, I. (2006) · Drug Metabolism Reviews · doi:10.1080/03602530600570040 · Cited by 293
Sun, C., Li, Y., Wu, Q., Luo, H., Sun, Y., Song, J., Lui, E. M., & Chen, S. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-262 · Cited by 286
Structural basis for plant lutein biosynthesis from α-carotene
Niu, G., Guo, Q., Wang, J., Zhao, S., He, Y., & Liu, L. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2001806117 · Cited by 79
Metadata
- Authors
- Coon, M. J.
- Venue
- Annual Review of Pharmacology and Toxicology
- Publisher
- Annual Reviews
- Published
- 2005-09-22
- Volume
- 45
- Issue
- 1
- Pages
- 1-25
- ISSN
- 0362-1642 (ISSN-L)
- 1545-4304
- OpenAlex
- W2107782429
- Cited by
- 395
- References
- 84
- FWCI
- 0.95
- Type
- journal article
- Language
- en
- Open access
- closed
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- Coon, M. J. (2005). CYTOCHROME P450: Nature's Most Versatile Biological Catalyst. Annual Review of Pharmacology and Toxicology. https://doi.org/10.1146/annurev.pharmtox.45.120403.100030
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
