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PHYSICAL CHEMISTRY OF NUCLEIC ACIDS
Open accessAbstract
[Figure: see text] ▪ Abstract The Watson-Crick double helix of DNA was first revealed in 1953. Since then a wide range of physical chemical methods have been applied to DNA and to its more versatile relative RNA to determine their structures and functions. My major goal is to predict the folded structure of any RNA from its sequence. We have used bulk and single-molecule measurements of thermodynamics and kinetics, plus various spectroscopic methods (UV absorption, optical rotation, circular dichroism, circular intensity differential scattering, fluorescence, NMR) to approach this goal.
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Citations
Cited by
An approach to computing electrostatic charges for molecules
Singh, U. C., & Kollman, P. A. (1984) · Journal of Computational Chemistry · doi:10.1002/jcc.540050204 · Cited by 3,428
Xia, T., SantaLucia, J., Burkard, M. E., Kierzek, R., Schroeder, S. J., Jiao, X., Cox, C., & Turner, D. H. (1998) · Biochemistry · doi:10.1021/bi9809425 · Cited by 1,140
Bacterial mercury resistance from atoms to ecosystems
Barkay, T., Miller, S. M., & Summers, A. O. (2003) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(03)00046-9 · Cited by 1,054
McGhee, J. D. (1976) · Biopolymers · doi:10.1002/bip.1976.360150710 · Cited by 309
Absorption spectrum of DNA for wavelengths greater than 300 nm
Sutherland, J. C., & Griffin, K. P. (1981) · Radiation Research · doi:10.2307/3575456 · Cited by 214
Metadata
- Authors
- Tinoco, I.
- Venue
- Annual Review of Physical Chemistry
- Publisher
- Annual Reviews
- Published
- 2002-10
- Volume
- 53
- Issue
- 1
- Pages
- 1-15
- ISSN
- 0066-426X (ISSN-L)
- 1545-1593
- OpenAlex
- W2118750431
- Cited by
- 789
- References
- 0
- FWCI
- 7.88
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.