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Cited by 789

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PHYSICAL CHEMISTRY OF NUCLEIC ACIDS

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Tinoco, Ignacio·2002·Annual Review of Physical Chemistry

Abstract

[Figure: see text] ▪ Abstract The Watson-Crick double helix of DNA was first revealed in 1953. Since then a wide range of physical chemical methods have been applied to DNA and to its more versatile relative RNA to determine their structures and functions. My major goal is to predict the folded structure of any RNA from its sequence. We have used bulk and single-molecule measurements of thermodynamics and kinetics, plus various spectroscopic methods (UV absorption, optical rotation, circular dichroism, circular intensity differential scattering, fluorescence, NMR) to approach this goal.

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Metadata

Authors
Tinoco, I.
Venue
Annual Review of Physical Chemistry
Published
2002-10
Volume
53
Issue
1
Pages
1-15
ISSN
  • 0066-426X (ISSN-L)
  • 1545-1593
OpenAlex
W2118750431
Cited by
789
References
0
FWCI
7.88
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: PHYSICAL CHEMISTRY OF NUCLEIC ACIDS. https://app.cochat.ai/papers/10.1146/annurev.physchem.53.082001.144341
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Tinoco, I. (2002). PHYSICAL CHEMISTRY OF NUCLEIC ACIDS. Annual Review of Physical Chemistry. https://doi.org/10.1146/annurev.physchem.53.082001.144341

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.